Clinical Trials Directory

Trials / Conditions / Triple Negative Breast Cancer (TNBC)

Triple Negative Breast Cancer (TNBC)

74 registered clinical trials studyying Triple Negative Breast Cancer (TNBC)51 currently recruiting.

StatusTrialSponsorPhase
Not Yet RecruitingA Nurse-Led, Coping and Supportive Intervention for Patients With Triple-Negative Breast Cancer
NCT07513311
Massachusetts General HospitalN/A
Not Yet RecruitingQLC5513 Alone or in Combination With QL1706 in Previously Treated Advanced or Metastatic TNBC.
NCT07509515
Fudan UniversityPhase 2
Not Yet RecruitingEvaluating Ovarian Toxicity Outcomes Following Immunotherapy in Patients With Triple-Negative Breast Cancer (T
NCT07527819
Peter MacCallum Cancer Centre, Australia
RecruitingDose Determining Study of EXS74539 (REC-4539) in Participants With Select Solid Tumors
NCT07517198
Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals, Inc.Phase 1
RecruitingBiolosion Combined Standard Neoadjuvant Therapy to Treat Triple-negative Breast Cancer
NCT06768931
Sun Yat-sen UniversityPhase 2
Not Yet RecruitingPreoperative Chemotherapy, Pembrolizumab and Low or High Dose RADiation in an Expansion Cohort of Node(+), Tri
NCT07276880
UNC Lineberger Comprehensive Cancer CenterPhase 2
RecruitingPREDICT-RD: ctDNA Surveillance in TNBC With Residual Disease
NCT07069595
UNC Lineberger Comprehensive Cancer CenterPhase 2
RecruitingQL1706 Plus Chemotherapy as Neoadjuvant Therapy in Triple-Negative Breast Cancer
NCT07342283
Affiliated Hospital of Nantong UniversityPhase 2
Active Not RecruitingMetabolic Flexibility in Patients With Early Triple-negative Breast Cancer
NCT07484776
Universidad Europea de MadridN/A
RecruitingDual-Target CAR-NK Cells for Advanced Breast Cancer (HER2+ and TNBC)
NCT07486089
Beijing BiotechPhase 1 / Phase 2
Not Yet RecruitingAdjuvant Intensification for LAR
NCT07407517
Fudan UniversityPhase 3
Not Yet RecruitingA Phase 1, Multicenter Imaging Study of LNTH-2403 in Participants With Locally Advanced or Metastatic Solid Tu
NCT07272642
Radiopharm Theranostics, LtdPhase 1
RecruitingA Study of MR001 in Patients With Locally Recurrent or Metastatic Advanced Triple-Negative Breast Cancer (TNBC
NCT07208149
Shenzhen Majory Biotechnology Co., Ltd.Phase 1 / Phase 2
Not Yet RecruitingThe Neoadjuvant Treatment of Early High-risk Triple Negative Breast Cancer With HRD Positive With Iparomlimab
NCT07187674
Harbin Medical UniversityN/A
Enrolling By InvitationA Phase 1/1b of RNDO-564 Single Agent or in Combination With Pembrolizumab in Bladder Cancer and Other Solid T
NCT07218003
Rondo TherapeuticsPhase 1
Not Yet RecruitingNeutrophil Biomarker Test for Predicting Clinical Benefit From Immunotherapy Based on Flow Cytometry Analysis
NCT07246759
OncoHost Ltd.
RecruitingA Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors
NCT07182149
Normunity AccelCo, Inc.Phase 1
RecruitingPQ203 in Advanced Malignant Tumors Including Triple Negative Breast Cancer
NCT07190469
ProteinQure Inc.Phase 1
Not Yet RecruitingCamrelizumab, Pirfenidone, and Chemotherapy in the Treatment of Advanced Triple-Negative Breast Cancer
NCT07161791
Harbin Medical UniversityPhase 1 / Phase 2
RecruitingA Phase III Study of ESG401 for Unresectable Recurrent or Metastatic Triple-Negative Breast Cancer
NCT06732323
Qilu Pharmaceutical Co., Ltd.Phase 3
Not Yet RecruitingSacituzumab Tirumotecan Plus Tagitanlimab in Previously Treated Locally Advanced or Metastatic Triple Negative
NCT07153965
Tianjin Medical University Cancer Institute and HospitalPhase 2
Not Yet RecruitingEvaluating Bemotuzumab to Improve the Efficacy of Neoadjuvant Chemotherapy for Triple-Negative Breast Cancer (
NCT06975644
Zhejiang Provincial People's HospitalN/A
Enrolling By InvitationA Long-Term Follow-Up Study of Participants Treated With A2 Biotherapeutics (A2 Bio) Gene Therapy (GT) Product
NCT06885424
A2 Biotherapeutics Inc.
RecruitingA Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors
NCT07020117
Aktis Oncology, Inc.Phase 1
RecruitingPersonalizing the Use of Pembrolizumab for Patients Who Have a Strong Response in Early Triple Negative Breast
NCT06606730
UNICANCERPhase 3
Not Yet RecruitingClinical Study of QL1706 in Combination With Olaparib for the Treatment of Patients With Previously Treated Ho
NCT07005583
Tianjin Medical University Cancer Institute and HospitalPhase 2
Active Not RecruitingA Study to Assess CLBR001+ABBV-461 in Subjects With Locally Advanced or Metastatic Breast Cancer
NCT06878248
Calibr, a division of Scripps ResearchPhase 1
RecruitingOPTImaL:Optimisation of Treatment for Patients With Low Stage Triple-negative Breast Cancer With High Stromal
NCT06476119
The Netherlands Cancer Institute
Not Yet RecruitingPaclitaxel Polymeric Micelles and Carboplatin in Combination With Iparomilimab and Tuvonralimab Neoadjuvant Th
NCT06910072
Cancer Institute and Hospital, Chinese Academy of Medical SciencesPhase 2 / Phase 3
RecruitingA Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors
NCT07029399
NiKang Therapeutics, Inc.Phase 1
RecruitingAK112 or Placebo Plus Nab-Paclitaxel as First-line Treatment in Inoperable Locally Advanced/ Metastatic Triple
NCT06767527
AkesoPhase 3
RecruitingNeoadjuvant Study of HIFU With or Without PD-1 Inhibitors Followed by Abraxane Plus Carboplatin in Triple-Nega
NCT07394387
The First Affiliated Hospital with Nanjing Medical UniversityPhase 2
RecruitingThe Optimal Radioimmunotherapy Combinations for Advanced TNBC
NCT06735131
Sun Yat-sen UniversityPhase 2
RecruitingBrAin Metastasis in tripLe Negateive Breast Cancer: IvoneScimab and Trop2 ADC
NCT06793332
Fudan UniversityPhase 2
Active Not RecruitingOptimal Combination of Adjuvant Radiotherapy and Immunotherapy for Breast Cancer
NCT07046195
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Not Yet RecruitingA Multicenter, Open-label Phase IIa Clinical Study to Evaluate the Efficacy and Safety of B1962 Injection in t
NCT06724263
Tasly Biopharmaceuticals Co., Ltd.Phase 2
Not Yet RecruitingJAK1 Inhibitor Ivarmacitinib Reversing Immunotherapy Resistance in TNBC
NCT06731153
Fudan UniversityPhase 2
RecruitingAll Trans Retinoic Acid Combined with Toripalimab+Chemotherapy for Locally Advanced Inoperable or Metastatic T
NCT06636981
Fudan UniversityPhase 2
RecruitingPlatform Study of ADC Rechallenge in ADC-treated Metastatic Breast Cancer
NCT06649331
Fudan UniversityPhase 2
Not Yet RecruitingJK-1201I in Triple Negative Breast Cancer Patients with Brain Metastases
NCT06586866
JenKem Technology Co., Ltd.Phase 2
RecruitingA Study of MOv18 IgE in Patients With Solid Tumours That Express Folate Receptor Alpha
NCT06547840
Epsilogen LtdPhase 1
RecruitingCircadian Rhythm Impact on TNBC Response to Neoadjuvant Immunotherapy
NCT06880029
Centro Hospitalar de Vila Nova de Gaia/Espinho, E.P.E.Phase 1 / Phase 2
RecruitingStudy of XB010 in Subjects With Solid Tumors
NCT06545331
ExelixisPhase 1
RecruitingPM8002 or Placebo Plus Nab-Paclitaxel as First-line Treatment in Inoperable Locally Advanced/Metastatic TNBC
NCT06419621
Biotheus Inc.Phase 3
Active Not RecruitingHome-Based Exercise Program During Neoadjuvant Treatment to Improve Fatigue and Quality of Life in Early HER2-
NCT06782698
Centro Hospitalar Universitário de Santo AntónioN/A
RecruitingEfficacy and Safety of Tenalisib in Patients With Metastatic Triple Negative Breast Cancer (TNBC)
NCT06189209
Rhizen Pharmaceuticals SAPhase 2
Active Not RecruitingStudy of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers
NCT05891171
Arcus Biosciences, Inc.Phase 1
Active Not RecruitingOCTANE: Adjuvant Liposomal Doxorubicin and Carboplatin for Early-stage Triple-negative Breast Cancer
NCT05949021
Mridula George, MDPhase 2
Active Not RecruitingA Study of ADRX-0706 in Select Advanced Solid Tumors
NCT06036121
Adcentrx TherapeuticsPhase 1
Recruitinga Single-arm, Single-center, Open Clinical Study
NCT06431100
Beijing Geekgene Technology Co., LTD
RecruitingStudy to Assess GTAEXS617 in Participants With Advanced Solid Tumors
NCT05985655
Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals, Inc.Phase 1 / Phase 2
Active Not RecruitingStudy of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR Inhibitor BBI-825, in Subj
NCT05827614
Boundless Bio, Inc.Phase 1
RecruitingA Study to Assess Safety, Tolerability and Imaging Characteristics of [68Ga]Ga-DPI-4452 and to Assess Safety,
NCT05706129
ITM Oncologics GmbHPhase 1 / Phase 2
RecruitingReal-World Study of Post-Resistance Treatment Strategies in Advanced Breast Cancer Following CDK4/6i, PIK3CA I
NCT07073755
Hunan Cancer Hospital
RecruitingJAB-2485 Activity in Adult Patients With Advanced Solid Tumors
NCT05490472
Jacobio Pharmaceuticals Co., Ltd.Phase 1 / Phase 2
CompletedStudy of B013 and Nab-Paclitaxel for Locally Advanced or Metastatic Triple Negative Breast Cancer
NCT05555706
Shanghai Jiaolian Drug Research and Development Co., LtdPhase 2 / Phase 3
RecruitingFudan University Shanghai Cancer Center Breast Cancer Precision Platform Series Study- Neoadjuvant Therapy
NCT05582499
Fudan UniversityPhase 2
Active Not RecruitingOnvansertib + Paclitaxel In TNBC
NCT05383196
Antonio Giordano, MDPhase 1 / Phase 2
RecruitingSolid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing
NCT04981119
A2 Biotherapeutics Inc.
RecruitingA Study of NX-1607 in Adults With Advanced Malignancies
NCT05107674
Nurix Therapeutics, Inc.Phase 1
UnknownNeoadjuvant Camrelizumab Plus Chemotherapy in Triple Negative Breast Cancer
NCT05088057
Aiping ShiPhase 2
TerminatedA Study on the Safety of GEN1044 (DuoBody®-CD3x5T4) in Patients With Malignant Solid Tumors
NCT04424641
GenmabPhase 1 / Phase 2
RecruitingPHOENIX DDR/Anti-PD-L1 Trial: A Pre-surgical Window of Opportunity and Post-surgical Adjuvant Biomarker Study
NCT03740893
Institute of Cancer Research, United KingdomPhase 2
Active Not RecruitingA Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ABBV-927 With ABB
NCT03893955
AbbViePhase 1
UnknownA Study of TQB2450 Injection and Anlotinib Hydrochloride Capsules to Treat Triple Negative Breast Cancer (TNBC
NCT03855358
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.Phase 1
TerminatedStudy of Safety and Efficacy of Novel Immunotherapy Combinations in Patients With Triple Negative Breast Cance
NCT03742349
Novartis PharmaceuticalsPhase 1
TerminatedA Phase 1 Study of [225Ac]-FPI-1434 Injection
NCT03746431
Fusion Pharmaceuticals Inc.Phase 1
WithdrawnQUILT-3.057: NANT Neoadjuvant Triple- Negative Breast Cancer (TNBC) Vaccine
NCT03554109
ImmunityBio, Inc.Phase 2
TerminatedA Phase I/Ib Study of NZV930 Alone and in Combination With PDR001 and /or NIR178 in Patients With Advanced Mal
NCT03549000
Novartis PharmaceuticalsPhase 1
CompletedStudy of Pembrolizumab (MK-3475) Plus Chemotherapy vs. Placebo Plus Chemotherapy for Previously Untreated Loca
NCT02819518
Merck Sharp & Dohme LLCPhase 3
TerminatedA Dose Exploration Study With Birabresib (MK-8628) in Participants With Selected Advanced Solid Tumors (MK-862
NCT02698176
Merck Sharp & Dohme LLCPhase 1
CompletedStudy to Explore the Safety, Tolerability and Efficacy of MK-3475 in Combination With INCB024360 in Participan
NCT02178722
Incyte CorporationPhase 1 / Phase 2
CompletedAZD8186 First Time In Patient Ascending Dose Study
NCT01884285
AstraZenecaPhase 1
No Longer AvailableExpanded Access to Veliparib
NCT03123211
AbbVie