| Active Not Recruiting | Metabolism, Excretion, and Mass Balance Study of Quemliclustat in Healthy Adult Participants (ARC-24) Healthy Participants | Phase 1 | 2026-02-03 |
| Recruiting | Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Rena Metastatic Clear Cell Renal Cell Carcinoma, Advanced Clear Cell Renal Cell Carcinoma | Phase 3 | 2025-09-08 |
| Completed | Drug-Drug Interaction Study of Casdatifan in Healthy Adult Participants (ARC-29) Healthy Participants | Phase 1 | 2025-05-02 |
| Active Not Recruiting | Study of Quemliclustat and Chemotherapy Versus Placebo and Chemotherapy in Patients With Metastatic Pancreatic Metastatic Pancreatic Ductal Adenocarcinoma | Phase 3 | 2024-12-13 |
| Active Not Recruiting | A Study of AB801 Monotherapy and Combination Therapy in Participants With Advanced Malignancies Advanced Cancer | Phase 1 | 2024-01-19 |
| Completed | A Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of AB801 in Healthy Volunteers Cancer | Phase 1 | 2023-10-16 |
| Active Not Recruiting | Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers Advanced Cancer, Advanced Malignancies, Bladder Cancer | Phase 1 | 2023-10-13 |
| Completed | A Relative Bioavailability Study and Food Effect Study of AB521 in Healthy Adult Volunteers Healthy Participants | Phase 1 | 2023-08-21 |
| Active Not Recruiting | A Clinical Trial of a New Combination Treatment, Domvanalimab and Zimberelimab, Plus Chemotherapy, for People Advanced Upper Gastrointestinal Tract Adenocarcinoma | Phase 3 | 2022-11-21 |
| Recruiting | A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors Clear Cell Renal Cell Carcinoma, Solid Tumors | Phase 1 | 2022-10-26 |
| Active Not Recruiting | A Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Gastrointestinal Tract Malignancies | Phase 2 | 2022-06-10 |
| Completed | A Study Investigating the Safety, Absorption, and Elimination of Radioactively Labeled Etrumadenant, a New Com Healthy Participants | Phase 1 | 2022-05-25 |
| Completed | A Study to Evaluate Pharmacokinetics (PK) of Etrumadenant Tablet and Capsule Formulations in Healthy Adult Par Healthy Participants | Phase 1 | 2022-02-10 |
| Completed | Study to Investigate the Safety, Tolerability, and Pharmacokinetic Profile With Oral AB521 in Healthy Voluntee Healthy Participants | Phase 1 | 2021-11-09 |
| Completed | A Drug-Drug Interaction Study to Evaluate the Effect of Itraconazole on the Pharmacokinetic Profile of Etrumad Healthy Participants | Phase 1 | 2021-10-20 |
| Completed | An Open Label Study Evaluating the Efficacy and Safety of Etrumadenant (AB928) Based Treatment Combinations in Metastatic Colorectal Cancer | Phase 1 / Phase 2 | 2021-05-10 |
| Completed | A Study to Evaluate AB308 in Combination With AB122 in Participants With Advanced Malignancies Advanced Solid Tumor, Non Small Cell Lung Cancer (NSCLC), Melanoma | Phase 1 | 2021-03-19 |
| Active Not Recruiting | Study Evaluating Effectiveness and Safety of Zimberelimab and Domvanalimab in Lung Cancer Non Small Cell Lung Cancer, Nonsquamous Non Small Cell Lung Cancer, Squamous Non Small Cell Lung Cancer | Phase 2 | 2021-02-08 |
| Completed | A Study to Investigate the Pharmacokinetic Profile of Oral AB680 in Healthy Volunteers Healthy Volunteers | Phase 1 | 2020-10-20 |
| Completed | Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer Prostatic Neoplasms, Castration-Resistant, Androgen-Resistant Prostatic Neoplasms, Castration Resistant Prostatic Neoplasms | Phase 1 / Phase 2 | 2020-07-07 |
| Completed | Study to Evaluate Monotherapy and Combination Immunotherapies in Participants With PD-L1 Positive Non-small Ce Non Small Cell Lung Cancer, Nonsquamous Non Small Cell Lung Cancer, Squamous Non Small Cell Lung Cancer | Phase 2 | 2020-05-28 |
| Active Not Recruiting | A Study to Evaluate the Safety and Tolerability of AB680 in Participants With Gastrointestinal Malignancies Advanced Pancreatic Cancer | Phase 1 | 2019-11-06 |
| Completed | Study to Evaluate Safety and Clinical Activity of AB122 in Biomarker Selected Participants With Advanced Solid Advanced Solid Tumors | Phase 1 | 2019-09-24 |
| Completed | A Study to Evaluate Immunotherapy Combinations in Participants With Lung Cancer Non Small Cell Lung Cancer Metastatic, Non Small Cell Lung Cancer, Nonsquamous Nonsmall Cell Neoplasm of Lung | Phase 1 | 2019-04-01 |
| Completed | A Study to Evaluate Immunotherapy Combinations in Participants With Gastrointestinal Malignancies GastroEsophageal Cancer, Colorectal Cancer | Phase 1 | 2018-11-18 |
| Completed | A Study to Investigate the Safety of AB680 in Healthy Volunteers Healthy Volunteers | Phase 1 | 2018-10-16 |
| Completed | A Study to Evaluate Safety/Tolerability of Immunotherapy Combinations in Participants With Triple-Negative Bre TNBC - Triple-Negative Breast Cancer, Ovarian Cancer | Phase 1 | 2018-10-15 |
| Completed | A Study to Evaluate the Safety and Tolerability of AB154 in Participants With Advanced Malignancies Solid Tumor, Unspecified, Adult | Phase 1 | 2018-09-12 |
| Completed | A Study to Evaluate the Safety and Tolerability of Immunotherapy Combinations in Participants With Advanced Ma Non-small Cell Lung Cancer, Squamous Cell Carcinoma of the Head and Neck, Breast Cancer | Phase 1 | 2018-07-24 |