| Recruiting | JAB-23E73 in Adult Participants With Advanced Solid Tumors With KRAS Alteration Advanced Solid Tumors | Phase 1 / Phase 2 | 2025-05-29 |
| Recruiting | A Phase I/IIa Study of JAB-23E73 in Patients With Advanced Solid Tumors Harboring KRAS Gene Alteration Advanced Solid Tumor | Phase 1 / Phase 2 | 2024-11-22 |
| Recruiting | JAB-30355 in Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation Solid Tumors | Phase 1 / Phase 2 | 2024-07-24 |
| Recruiting | JAB-2485 Activity in Adult Patients With Advanced Solid Tumors Solid Tumors, ER+ Breast Cancer, Triple Negative Breast Cancer, TNBC | Phase 1 / Phase 2 | 2022-12-20 |
| Completed | JAB-BX102 Monotherapy and Combination With Pembrolizumab in Adult Patients With Advanced Solid Tumors Solid Tumor | Phase 1 / Phase 2 | 2022-08-18 |
| Completed | JAB-21822 Activity in Adult Patients With Advanced Solid Tumors Harboring KRAS G12C Mutation Advanced Solid Tumor, NSCLC, CRC | Phase 1 / Phase 2 | 2021-09-03 |
| Recruiting | A First-in-Human, JAB-8263 in Adult Patients With Advanced Tumors NSCLC, SCLC, CRPC | Phase 1 / Phase 2 | 2021-05-07 |
| Completed | JAB-3068 Activity in Adult Patients With Advanced Solid Tumors Advanced Solid Tumor, Esophageal Squamous Cell Carcinoma, Non Small Cell Lung Cancer | Phase 1 / Phase 2 | 2021-04-26 |
| Completed | A First-in-Human Study of JAB-8263 in Adult Patients With Advanced Solid Tumors Solid Tumors, Adult | Phase 1 | 2020-11-23 |
| Completed | A First-in-Human, Phase 1 Study of JAB-3312 in Adult Patients With Advanced Solid Tumors Non-small Cell Lung Cancer, Colorectal Cancer, Pancreatic Ductal Carcinoma | Phase 1 | 2019-09-26 |
| Completed | A First-in-Human Study of JAB-3068 (SHP2 Inhibitor) in Adult Patients With Advanced Solid Tumors in China Non-small Cell Lung Cancer, Head and Neck Cancer, Esophageal Cancer | Phase 1 / Phase 2 | 2018-11-20 |
| Completed | A First in Human, Dose Escalation Study of JAB-3068 (SHP2 Inhibitor) in Adult Patients With Advanced Solid Tum Non-small Cell Lung Cancer, Head and Neck Cancer, Esophageal Cancer | Phase 1 | 2018-04-23 |