Trials / Conditions / Total Knee Replacement

Total Knee Replacement

147 registered clinical trials studyying Total Knee Replacement — 23 currently recruiting.

Status	Trial	Sponsor	Phase
Not Yet Recruiting	Binaural Beats for Postoperative Pain and Anxiety Reduction NCT07437469	University of Miami	N/A
Not Yet Recruiting	Dressing-related Experiences and Surgical Site Self-care in Hip and Knee Replacement: an Observational Cohort NCT07471243	Bournemouth University	—
Not Yet Recruiting	Cooling of the Knee After Total Knee Arthroplasty NCT07416721	Clinical Center of Vojvodina	N/A
Not Yet Recruiting	Analgesic Efficacy of Pre-Operative Dose of Palmitoylethanolamide in Patients Undergoing Total Knee Arthroplas NCT07330765	Abdelrahman Gaber Sayed Elkhateeb	Phase 1 / Phase 2
Not Yet Recruiting	The Feasibility of a Nurse-Initiated Weighted Blanket in Orthopedic Surgical Patients Undergoing Total Knee Ar NCT07219329	NYU Langone Health	N/A
Recruiting	Mako Cementless TKA vs Mako Cemented TKA NCT06929871	University College, London	N/A
Recruiting	Comparison of the Effects of Apixaban on Thrombin Generation in Patients With de Novo Multiple Myeloma NCT06474182	Centre Hospitalier Universitaire de Saint Etienne	N/A
Recruiting	An Open Label Data Collection Study of My Connect Post-Op, a Post-Operative Communication Tool NCT07120191	Concentra AI, inc	—
Completed	Postural Correctors & Activity Trackers in Total Knee Replacement Rehab NCT06877845	Riphah International University	N/A
Active Not Recruiting	Efficacy of Kinesiotaping During Rehabilitation Following Total Knee Replacement Surgery NCT06831682	SRH Gesundheitszentrum Bad Herrenalb	N/A
Enrolling By Invitation	The Effect of TENS on Early Patient Outcomes After Total Knee Arthroplasty NCT07155837	Cukurova University	N/A
Not Yet Recruiting	Remote Multichannel Monitoring of Patients With Chronic DIseAses Using Speech technoLogies Based On Artificial NCT06644339	I.M. Sechenov First Moscow State Medical University	N/A
Completed	Comparative Effect of Instrument Assisted Soft Tissue Mobilization and Cross Fiber Massage in Patients With To NCT07361770	Rashid Latif Medical College	N/A
Recruiting	The Effect of Abdominal Massage and Warm Application on Excretory Activity in Patients Undergoing Total Knee R NCT06578936	Ayşe Demirtaş	N/A
Recruiting	A Post-market Observational ORIGIN® CR Clinical Study NCT05607966	Symbios Orthopedie SA	—
Active Not Recruiting	Comparing Temperature in Burr vs Saw Cutting for Knee Arthroplasty NCT07010809	East Suffolk and North Essex NHS Foundation Trust	—
Completed	Analysis of Postoperative Analgesic of Different Nerve Blocks for Total Knee Replacement Surgery NCT06521619	Fu Jen Catholic University Hospital	—
Active Not Recruiting	Metal Ion Concentrations After Total Knee Arthroplasty NCT06447922	Mayo Clinic	—
Recruiting	Comparison of Pivotal Medial Polyethylene Versus Ultra-congruent in Total Knee Arthroplasty NCT06676189	University Hospital, Clermont-Ferrand	N/A
Recruiting	Movement Dynamics of Knee Osteoarthritis and Total Knee Replacement NCT06829433	University of Portsmouth	—
Recruiting	Total Knee Replacement Under Spinal Anesthesia, Comparison of Postoperative Recovery Versus General Anesthesia NCT07275983	University Hospital, Strasbourg, France	—
Recruiting	Knee4Life Project: Empowering Knee Recovery After Total Knee Replacement Through Digital Health NCT06429462	University of Exeter	—
Enrolling By Invitation	Persona IQ Cohort Study NCT06089291	Zimmer Biomet	—
Completed	Mindfulness Meditation Intervention Study NCT06180486	Hospital for Special Surgery, New York	N/A
Completed	Effects of OEP on Rehabilitation Outcomes on TKR Patients NCT06190977	Riphah International University	N/A
Completed	The Effect of Epidural Anesthesia on Optic Nerve Sheath Diameter Measurements in Total Knee Prosthesis Surgery NCT07458321	Bursa City Hospital	N/A
Unknown	Effect of Mindfulness on Pain After Total Knee Arthroplasty NCT06118073	Rothman Institute Orthopaedics	N/A
Completed	Aromatherapy in Total Knee Replacement NCT06045078	Hospital for Special Surgery, New York	N/A
Unknown	Wound Healing in Primary TKA NCT06007599	Rothman Institute Orthopaedics	N/A
Completed	Genicular and Anterior Femoral Cutaneous Nerve Blocks for Total Knee Arthroplasty NCT05980546	Hospital for Special Surgery, New York	Phase 4
Recruiting	Tapentadol vs Tramadol in Total Knee Arthroplasty NCT06269770	University of Thessaly	Phase 4
Active Not Recruiting	Knee Arthroplasty Activity Trial NCT04107649	Brigham and Women's Hospital	N/A
Active Not Recruiting	ORIGIN® PS Modular & Associated Instruments NCT06628050	Symbios Orthopedie SA	—
Completed	Mepivacaine Vs. Bupivacaine Spinal for TKA NCT05765682	Medical University of South Carolina	N/A
Recruiting	Yale Steroid Enhanced Versus Exparel Nerveblock TKA Part 2 NCT05736549	Yale University	Phase 2
Recruiting	Effects of Fall Prevention Program on the Number of Falls Among Elderly Following Total Knee Replacement NCT05642260	Ministry of Health, Kuwait	N/A
Completed	Combined Adductor&Sciatic Nerve Block vs Femoral&Sciatic Nerve Block in Total Knee Replacement Surgery NCT05648708	Bakirkoy Dr. Sadi Konuk Research and Training Hospital	N/A
Active Not Recruiting	ALknee Follow-up Study of the Cementless ATTUNE Rotating Platform and the Cementless LCS Rotating Platform Kne NCT05623215	Spaarne Gasthuis	—
Completed	Qualitative Interviews With Healthcare Professionals NCT05597046	Invibio Ltd	—
Completed	Assessing Function and Pain After Total Knee Arthroplasty With Combined Femoral and Popliteal Nerve Block NCT06196359	University of Haifa	N/A
Completed	Postoperative Pain and Blood Loss of Non-use Compared to Partial-use of a Tourniquet in Bilateral Total Knee R NCT06815445	Queen Savang Vadhana Memorial Hospital, Thailand	N/A
Recruiting	Yale Steroid Enhanced Versus Exparel Nerveblock TKA RCT Study NCT05279092	Yale University	Phase 2
Completed	Intrathecal Morphine Versus Morphine-dexmedetomidine Combination for Postoperative Pain Control After Total Kn NCT05439564	Tanta University	N/A
Completed	Robotic Assisted TKA NCT06062615	Rothman Institute Orthopaedics	N/A
Completed	Evaluating the Feasibility and Effectiveness of Using a Smartphone Application During Rehabilitation in Patien NCT05434767	Singapore General Hospital	N/A
Unknown	Innovative Gait Training for People With Knee Osteoarthritis Using Dual Belt Treadmill NCT05958212	The Hong Kong Polytechnic University	N/A
Recruiting	TRabecular Metal Economic and Clinical Knee Trial NCT04677907	NHS Greater Glasgow and Clyde	N/A
Completed	Meloxicam for Pain Management After Total Joint Arthroplasty (TJA) NCT05291598	University of Miami	Phase 3
Unknown	The Effect of Laser Acupuncture Intervention to the Prognosis After TKR Surgery NCT05263856	China Medical University Hospital	N/A
Unknown	Influence of Closed Suction Drainage After Total Knee Replacement. NCT03995160	Medical University of Warsaw	N/A
Completed	Reliability and Validity of the 2-Minute Step Test in Patients With Knee Arthroplasty NCT05064943	Kutahya Health Sciences University	—
Unknown	The Effects of Transcutaneous Electrical Nerve Stimulation in Patients With Total Knee Replacement NCT05115565	Bozok University	N/A
Completed	Otago Exercise in Patient With Total Knee Replacement NCT05137028	Riphah International University	N/A
Terminated	Physica System KR Vs Physica System CR (K-20) NCT04594447	Limacorporate S.p.a	N/A
Terminated	Bone Wax Use for Hemostasis During Primary Unilateral Total Knee Arthroplasty NCT04992052	Northwell Health	N/A
Unknown	Impact of Adductor Canal Block on Functional Recovery NCT04814303	Assiut University	N/A
Terminated	Use of the DJO Brace With the Motion Intelligence Platform in the Postoperative Total Knee Arthroplasty Patien NCT04655703	Northwell Health	N/A
Unknown	Comparison of Surgical Site Infection After Skin Closure by Prolene or Staples in Bilateral Knee Arthroplasty NCT04492852	Indus Hospital and Health Network	N/A
Terminated	Adductor Canal Block NCT04513145	OrthoCarolina Research Institute, Inc.	Phase 2 / Phase 3
Completed	Treatment of Post-Operative Pain Following Orthopedic Surgery With SPRINT® Peripheral Nerve Stimulation (PNS) NCT04341948	SPR Therapeutics, Inc.	N/A
Terminated	Observational Study to Evaluate Clinical Performance and Safety in Total Knee Arthroplasty NCT04872855	Corin	—
Completed	Hospital-based Usual cAre Versus Tele-monitoring Rehabilitation NCT04352972	Singapore General Hospital	N/A
Recruiting	A Study to Compare Different Ways of Steroid Administration After Total Knee Implantation NCT04432012	Christian Candrian	Phase 4
Suspended	TKR Rehabilitation Through the Immersive Virtual Reality in Aquatic Scenarios NCT04241172	IRCCS San Raffaele Roma	N/A
Unknown	Influence of Single Session of Aerobic Exercise on Acute Pain and Function in Patients After Total Knee Replac NCT04206709	University of Haifa	N/A
Completed	Neurotoxicity and Cardiotoxicity in Total Joint Arthroplasty NCT04166539	Mayo Clinic	—
Completed	The Efficacy of Low-load Blood Flow Restricted Resistance Before TKR NCT04081493	University of Aarhus	N/A
Completed	Motor Performance Modulation After Total Knee Replacement NCT03997565	Istituto Clinico Humanitas	—
Completed	Multi-variable Prediction Model of Total Knee Replacement Outcome NCT03894514	University of Valencia	—
Completed	Exercise Device in Total Knee Arthroplasty NCT03876431	Istanbul University	N/A
Completed	Antibiotic Elution in Total Knee Arthroplasty NCT03928522	Washington University School of Medicine	Phase 4
Completed	Efficacy and Safety of Chuna Manual Treatment as an Adjunctive Therapy After Total Knee Arthroplasty: A Study NCT03625050	Gachon University Gil Oriental Medical Hospital	Phase 2
Unknown	Clinical and Functional Outcome of the Gemini SL Fixed Bearing at Midterm Follow-up NCT03575546	Waldemar Link GmbH & Co. KG	—
Completed	Novel Strategies for Personalized Clinical Decisions in Knee Arthroplasty NCT05900453	University of Colorado, Denver	—
Completed	Safety and Activity of F14 for Management of Pain Following Total Knee Replacement NCT03541655	Arthritis Innovation Corporation	Phase 2
Unknown	Effects of Combined Topical and Systemic Steroid Administrations on Better Early Postoperative Pain Management NCT03901768	The University of Hong Kong	Phase 4
Unknown	Prediction of Leg Length Discrepancy After Unilateral Total Knee Replacement in Varus Deformity NCT03502382	Assiut University	N/A
Completed	Effect Of Counselıng NCT04916717	Uşak University	N/A
Unknown	The Clinical Observation on Taping After Total Knee Replacement NCT03340584	Second Affiliated Hospital of Wenzhou Medical University	N/A
Completed	Electrical Stimulation for the Treatment of Pain Following Total Knee Arthroplasty Using the SPRINT Beta Syste NCT03286543	SPR Therapeutics, Inc.	N/A
Active Not Recruiting	Kinematic Versus Mechanical Alignment in Total Knee Replacement NCT04384913	Hannover Medical School	—
Completed	Using Mobilization Exercises on Total Knee Arthroplasty Rehabilitation NCT03215160	Istanbul University	N/A
Completed	CREATION Health Readmission Risk Assessment Tool NCT03424382	AdventHealth	—
Terminated	Study to Evaluate Long Term Performance and Safety of the Knee Prosthesis (HLS KneeTec Deep Dish) NCT05211141	Corin	—
Completed	Adductor Under Sartorial Canal Catheter (KTT) Versus Femoral Catheter (KTF) in a Quick Rehabilitation Process NCT02873637	Centre Hospitalier Departemental Vendee	N/A
Completed	Knee Replacement Outcome Predicted by Physiotherapists NCT02982785	Marius Henriksen	—
Completed	Virtual Reality Rehabilitation in Patients With Total Knee Replacement NCT03454256	IRCCS San Raffaele Roma	N/A
Completed	Virtual vs. Traditional Physical Therapy Following Total Knee Replacement NCT02914210	Duke University	N/A
Terminated	Predicting, Understanding and Speeding Recovery After TKA NCT02685735	Wake Forest University Health Sciences	Phase 4
Unknown	Pre-operative Radiological Measurement to Assess Femur Rotational Alignment NCT02817737	Xi'an Honghui Hospital	—
Terminated	Patient Oriented Discharge Summary Impact Study NCT02673892	University Health Network, Toronto	N/A
Completed	Effect of the PainCoach App on Pain and Opiate Use After Total Knee Replacement NCT03961152	Kliniek ViaSana	N/A
Completed	Fluoroscopic Analysis of Total Knee Replacement With a Kinematic Retaining or a Posterior Stabilized Design NCT02706990	Limacorporate S.p.a	N/A
Terminated	A Comparison of Anaesthetic Methods for Total Knee Replacement Surgery NCT02249481	University Hospital Plymouth NHS Trust	N/A
Terminated	Influence of Manual Lymph Drainage During Hospitalization on Swelling, Function and Pain in Patients After Tot NCT01657149	Rabin Medical Center	N/A
Completed	Study Comparing GAP-Flex to CPM Therapy in Treatment of TKR NCT02670499	Xeras Medical Technologies	N/A
Completed	Electrical Stimulation for the Treatment of Pain Following Total Knee Arthroplasty (TKA) Using the SPRINT Syst NCT02468934	SPR Therapeutics, Inc.	N/A
Unknown	Comparison of Three Knee Replacements NCT03339557	Coxa, Hospital for Joint Replacement	N/A
Unknown	Patient Recovery After Knee Replacement Surgery NCT03518866	Bev Hoddell	—
Unknown	Regional Anesthesia for Knee Prothesis Surgery NCT02451605	University of Liege	N/A
Completed	Physica KR Fluoroscopy Study NCT02655809	Limacorporate S.p.a	N/A
Completed	Pain Neuroscience Education in Total Knee Arthroplasty NCT03231566	University of Nevada, Las Vegas	N/A
Withdrawn	Study to Observe Safety of Xarelto in VTE Prophlylaxis After Elective TKR (Total Knee Replacement) or THR (Tot NCT01523418	Bayer	—
Completed	Effects of Virtual Reality Rehabilitation in Patients With Total Knee Arthroplasty NCT02413996	I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio	N/A
Unknown	Negative Pressure Wound Therapy -PREVENA in Prevention of Infections After Total Knee Arthroplasty (TKA) NCT02118558	Hadassah Medical Organization	Phase 2
Completed	Action Observation in Knee Replacement NCT02707419	Fondazione Don Carlo Gnocchi Onlus	N/A
Completed	Post Op Home Monitoring After Joint Replacements NCT02143232	Ottawa Hospital Research Institute	N/A
Completed	How Total Knee Prosthesis Dessigns Influence in Quality of Live NCT02050438	Corporacion Parc Tauli	—
Completed	Effectiveness of Osteopathy in the Preoperative Treatment of Postoperative Pain in Patients Undergoing Total K NCT01989117	Hospital Ambroise Paré Paris	—
Completed	Safety and Efficacy of TeaRx Xa Factor Direct Inhibitor Versus Enoxaparin as a Venous Thromboembolic Events (V NCT03088358	TeaRx LLC	Phase 2
Completed	Comparison of Continuous Femoral Nerve Block and Adductor Canal Block After Total Knee Replacement Therapy NCT02125903	Philipps University Marburg	N/A
Completed	Evaluating the Influence of the Strategy Intraoperative Anesthetic (Desflurane Versus Propofol) on Cognitive a NCT02036736	Assistance Publique - Hôpitaux de Paris	Phase 2
Completed	Progression of Health Related Quality of Life of Patients Waiting for Total Knee Arthroplasty NCT03492320	Dr. Ho Ki Wai	—
Unknown	Ultrasound Guided Obturator Nerve Block for Total Knee Replacement (TKR) NCT01755117	Larissa University Hospital	N/A
Completed	Controlled Study of Kneehab XP for Patients Undergoing Total Knee Replacement NCT01548040	Theragen Inc.	N/A
Terminated	Open Label Study to Collect Clinical Data to Document Clinical Performance and Safety in Total Knee Arthroplas NCT04727060	Corin	—
Completed	Evaluation of Patellar Crepitus Following Total Knee Arthroplasty NCT01340144	Colorado Joint Replacement	—
Completed	The Use of Fibrin Sealant to Reduce Bleeding After Total Knee Replacement NCT01816282	University of Milan	N/A
Completed	Postoperative Knee Strength Following Total Knee Replacement: A Double-Blinded Randomized Comparison Study NCT01620047	University of South Florida	N/A
Unknown	The Analgesic Efficacy of Local Anaesthetic Wound Infiltration Versus Intrathecal Morphine for Total Knee Repl NCT01312415	Cork University Hospital	Phase 4
Completed	Long Term Foundation Knee Study NCT01274546	Encore Medical, L.P.	—
Unknown	Prophecy Guide Outcomes in Total Knee Replacement Surgery NCT01163708	Global Orthopaedic Technology	Phase 4
Completed	Continuous Postoperative Pulse Oximetry in Patients Presenting for Total Hip and Total Knee Replacement NCT01189565	Medical University of South Carolina	—
Withdrawn	Biochemical Approach to Measuring Surgical Trauma NCT01037400	Hamilton Health Sciences Corporation	—
Terminated	ChloraPrep Versus Betadine for Elective Knee Replacement Surgery NCT01184196	Central DuPage Hospital	Phase 4
Terminated	LEGION™ Primary Safety and Efficacy NCT04040985	Smith & Nephew, Inc.	N/A
Completed	Hydrotherapy Versus Physiotherapy for Short-term Rehabilitation After Primary TKR NCT00878358	Hadassah Medical Organization	N/A
Completed	The Effects of Arixtra on Wound Drainage Following Total Joint Arthroplasty NCT00909064	Paul Di Cesare,MD	Phase 4
Completed	The Effect of Patellar Eversion on Functional Outcomes in Primary Total Knee Arthroplasty NCT01777009	Northwell Health	N/A
Unknown	Effectiveness of Acupuncture as an Adjunct to Rehabilitation After Knee Arthroplasty NCT00935155	Back and Rehabilitation Center, Copenhagen	N/A
Completed	Audiovisual Videodisc Education and Modification of Expectations With Total Knee Replacement (TKR) NCT01463930	Parc de Salut Mar	N/A
Withdrawn	Clinical Trial for Fibrin Sealant in Knee Surgery NCT00440921	Sanquin Research & Blood Bank Divisions	N/A
Completed	Comparative Pain Control Between 0.2 or 0.3 Spinal Morphine and 0.25 or 0.5 % Bupivacaine for FNB After TKA NCT00795223	Mahidol University	Phase 4
Terminated	Embolic Events Detected During Total Knee Arthroplasty With the Use of RIA (Reamer-Irrigator-Aspirator) NCT00815958	Ohio State University	N/A
Completed	Morphine Consumption in Joint Replacement Patients, With or Without Gabapentin Treatment NCT01307202	McMaster University	N/A
Completed	X-3 Polyethylene Survival Outcomes Study NCT00493792	Mayo Clinic	N/A
Completed	Total Knee Arthroplasty And Thromboembolism: A Comparison Between Two Surgical Techniques NCT00755300	University of California, Davis	—
Completed	Femoral Block With or Without Ropivacaine for Analgesia After Total Knee Replacement (TKR) NCT00910013	Hopital de l'Enfant-Jesus	Phase 1 / Phase 2
Unknown	Static and Dynamic Balance in Correlation With Quality of Life, in Primary Total Knee Replacement NCT00256958	Hadassah Medical Organization	Phase 1 / Phase 2
Withdrawn	Total Knee Arthroplasty Outcome Study NCT00160797	University of Florida	Phase 4
Completed	New Oral Anticoagulant Therapy for the Prevention of Blood Clots Following Hip or Knee Replacement Surgery NCT00074828	Eli Lilly and Company	Phase 2
Unknown	Time-dependent Improvement of Functional Outcome Following LCS Rotating Platform TKR NCT01030848	Vestre Viken Hospital Trust	—
Completed	Predictors of Poor Outcomes in 1038 Sigma Knees NCT01515449	NHS Fife	—
Completed	10 Year Outcome of Total Knee Replacement (TKR) Using Sigma Prosthesis NCT01522781	NHS Fife	—
Completed	Patellar Resurfacing Versus Patellar Retention in Total Knee Arthroplasty - A Randomized Clinical Trial NCT01500252	University of Alberta	Phase 4
Terminated	Navigated EM Total Knee Replacement: Accuracy Study NCT00512421	Hadassah Medical Organization	—
Completed	Flexion Versus Extension Soft Tissue Repair in Total Knee Arthroplasty NCT02067533	Isfahan University of Medical Sciences	N/A