NCT06829433

Movement Dynamics of Knee Osteoarthritis and Total Knee Replacement

Quantifying the Movement Dynamics of Adults Living With Total Knee Arthroplasty and Knee Osteoarthritis

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 36 (estimated)
• Sponsor: University of Portsmouth · Academic / Other
• Sex: All
• Age: 40 Years – 85 Years
• Healthy volunteers: Accepted

Summary

This research aims to explore differences in walking and functional movement mechanics, exercise response, and physical activity between people with osteoarthritis (OA), those who have undergone total joint replacement, and healthy individuals.

Detailed description

People living with OA tend to be less physically active than those without the disease, which is often due to pain, stiffness and joint instability. This reduction in physical activity can lead to additional health problems down the line. When the disease becomes severe, joint replacement surgeries are sometimes performed to relieve pain and improve individuals' quality of life. However, despite reducing pain, there is little evidence to show that joint replacement surgeries encourage individuals to return to healthy physical activity levels. Reasons for the lack of change may include a failure to address unhealthy walking and movement patterns which could still be causing pain and instability and reduced physical fitness levels. By investigating these reasons, we hope that findings from this study will help to inform future interventions that improve clinical outcomes and quality of life for individuals with OA and post-joint replacement.

Conditions

• Knee Osteoarthritis
• Total Knee Replacement

Interventions

Type	Name	Description
OTHER	No intervention	Observational cross-sectional study

Timeline

• Start date: 2024-05-07
• Primary completion: 2026-01-01
• Completion: 2026-09-01
• First posted: 2025-02-17
• Last updated: 2025-02-21

Locations

1 site across 1 country: United Kingdom