NCT05900453

Novel Strategies for Personalized Clinical Decisions in Knee Arthroplasty

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 675 (actual)
• Sponsor: University of Colorado, Denver · Academic / Other
• Sex: All
• Age: 40 Years
• Healthy volunteers: Not accepted

Summary

This study will compare the postoperative recovery of two patient cohorts who attended outpatient physical therapy at two clinics in the Greenville, South Carolina area. The Usual Care cohort received care according to each clinic's pre-existing care guidelines. The CDS Cohort received care informed by a new clinical decision support (CDS) tool.

Detailed description

In this cohort study, the investigators will use regression to examine whether CDS tool exposure was associated with patient outcomes after total knee replacement. Linear mixed effect models will be used for continuous outcomes that have multiple assessment points per patient. For count outcomes (e.g., visit utilization), the investigators will use Poisson/negative binomial regression or linear regression with appropriate outcome transformations.

Conditions

• Total Knee Replacement

Interventions

Type	Name	Description
OTHER	Clinical decision support (CDS) tool	The web-based clinical decision support (CDS) tool uses patient information (e.g., age, sex, BMI, perioperative status) to create personalized predictions of recovery following knee replacement. The CDS tool predicts range of motion, physical function, and pain recovery. Clinicians can use these predictions to (1) inform patients of their expected prognosis, (2) monitor patients' recovery against their predicted recovery, and (3) tailor treatments according to individual patients' needs. Clinicians were provided with basic training for how to use the CDS tool, and were given examples of how to integrate it into clinical care. However, the CDS tool did not dictate any treatment decisions; clinicians were free to use the CDS tool at their discretion to inform decision making.

Timeline

• Start date: 2018-05-15
• Primary completion: 2022-12-30
• Completion: 2022-12-30
• First posted: 2023-06-12
• Last updated: 2023-09-28

Locations

1 site across 1 country: United States