| Not Yet Recruiting | A Multi-Center Study Assessing the Safety and Efficacy of the LEGION Medial Stabilized (MS) Insert in Patients Inflammatory Arthritis, Primary Total Knee Arthroplasty Due to Degenerative Joint Disease (Primary Diagnosis of Osteoarthritis), Post-traumatic Arthritis | — | 2025-11-01 |
| Recruiting | Post-Market Clinical Study to Evaluate the Safety and Effectiveness of REFLEX ULTRA 45 for Coblation Inferior Nasal Obstruction Due to Inferior Turbinate Hypertrophy | N/A | 2025-07-02 |
| Enrolling By Invitation | A Post Approval Multicenter 10 Year Follow-up Observational Trial of Marketed Product - MP01 vs. Surgical Stan Knee Injuries, Joint Surface Knee Lesions | — | 2025-05-05 |
| Completed | Human Participant Study of a Prototype Multilayer Foam Dressing on Intact Skin. Healthy | N/A | 2025-01-27 |
| Completed | Human Participant Study of Prototype Non-medicated Multilayer Foam Dressings on Intact Skin Healthy | N/A | 2024-10-28 |
| Active Not Recruiting | A Multi-Centre Study in Patients Undergoing Total Hip Arthroplasty With the Smith+Nephew CATALYSTEM™ Primary H Total Hip Arthroplasty (THA), Osteoarthritis, Degenerative Joint Disease | — | 2024-09-26 |
| Terminated | A Clinical Study on New Negative Pressure Wound Therapy Dressing in the Management of Chronic & Acute Wounds Chronic Wounds, Acute Wounds | — | 2024-05-30 |
| Recruiting | AETOS Shoulder System Shoulder Osteoarthritis, Shoulder Arthritis | — | 2024-03-05 |
| Terminated | PICO Venous Leg Ulcers (VLU) Reimbursement Study Venous Insufficiency, Venous Leg Ulcer | N/A | 2023-12-29 |
| Withdrawn | Study to Evaluate Patient Outcomes and Safety and Effectiveness of Robotic Assisted Unicompartmental Knee Repl Arthroplasty, Replacement, Knee, Unicompartmental Knee Arthroplasty | N/A | 2023-11-21 |
| Recruiting | Evaluation of Outcomes Following In-office Tympanostomy Using the Tula® System: a Prospective, Multi-center Re Otitis Media With Effusion, Acute Otitis Media, Otitis Media | — | 2023-06-15 |
| Recruiting | Use of the REGENETEN™ Bioinductive Implant System in High Grade Partial-thickness Tears Rotator Cuff Injuries | N/A | 2022-08-30 |
| Withdrawn | Evaluate the Performance of JOURNEY II CR and JOURNEY II BCS in TKA Populations Arthroplasty, Replacement, Knee | N/A | 2022-08-28 |
| Terminated | Evaluate the Performance of JOURNEY II CR in TKA Populations Arthroplasty, Replacement, Knee | — | 2022-03-03 |
| Recruiting | Study to Evaluate the Safety and Effectiveness of the REAL INTELLIGENCE™ CORI™ in Total Knee Arthroplasty (TKA Arthroplasty, Replacement, Knee | N/A | 2022-02-12 |
| Terminated | Study to Evaluate the Safety and Effectiveness of REAL INTELLIGENCE™ CORI™ in Unicondylar Knee Arthroplasty (U Non-inflammatory Degenerative Joint Disease, Osteoarthritis, Avascular Necrosis | N/A | 2022-02-12 |
| Active Not Recruiting | To Evaluate the Performance of the CORI™ KNEE TENSIONER as an Accessory to the CORI™ Surgical System. Arthroplasty, Replacement, Knee | N/A | 2022-02-10 |
| Completed | Safety and Performance Study of the FAST-FIX FLEX System for Meniscal Repairs and Meniscal Transplantations Meniscus Tear | — | 2022-01-20 |
| Active Not Recruiting | A Global Clinical Study Investigating the Safety and Effectiveness of Smith and Nephew's Porous Knee System in Osteoarthritis, Post-traumatic Arthritis, Rheumatoid Arthritis | — | 2021-12-21 |
| Completed | Study to Evaluate the Safety and Effectiveness of REAL INTELLIGENCE™ CORI™ in Knee Arthroplasty Procedures Arthroplasty, Replacement, Knee | N/A | 2021-02-17 |
| Completed | Safety of Treatment of Shoulder Repair Rotator Cuff | — | 2021-01-26 |
| Terminated | REGENETEN™ Bioinductive Implant System in Full-thickness Tears Rotator Cuff Injuries | N/A | 2020-12-07 |
| Terminated | Circumferential Compression STITCH Repairs of Complex and Horizontal Cleavage Meniscal Tears Meniscus Tear, Retention; Meniscus | — | 2020-11-13 |
| Completed | Safety and Performance of ENTACT Septal Staple System for Septoplasty Septoplasty | — | 2020-10-22 |
| Recruiting | Evaluation Of Outcomes Following Rotator Cuff Repair Using the REGENETEN Bioinductive Implant: A Prospective, Rotator Cuff Injuries | — | 2020-10-01 |
| Terminated | Study to Evaluate the PICO 14 Negative Pressure Wound Therapy System in the Management of Acute and Chronic Wo Surgical Incision, Ulcer Foot, Ulcer Venous | — | 2020-09-22 |
| Active Not Recruiting | Safety and Effectiveness Study of OR3O™ Dual Mobility System in THA Advanced Degeneration of the Hip Joint, Revision of the Hip Joint | — | 2020-07-27 |
| Completed | Safety and Effectiveness of BIOSURE RG in Cruciate Ligaments Reconstruction in Chinese Cruciate Ligament Reconstruction, Knee | N/A | 2019-12-17 |
| Completed | Retro-prospective Study of Safety & Performance of Round XTENDOBUTTON™ Fixation Device Post Knee Repair Knee Reconstruction | — | 2019-11-21 |
| Completed | A Study of the Safety and Performance of the MINITAC◊ Titanium 2.0 Suture Anchor Hallux Valgus Repairs, Medial or Lateral Instability Repairs/Reconstructions, Achilles Tendon Repairs/Reconstructions | — | 2019-10-25 |
| Terminated | Safety Study of Treatment of Leg Fractures Tibial Fractures | — | 2019-09-20 |
| Completed | Safety and Performance of MICRORAPTOR™ Suture Anchors in Shoulder and Hip Labral Tear, Glenoid, Acetabular Labrum Tear, Bankart Lesions | — | 2019-08-01 |
| Completed | Performance, Safety and Efficacy of NPWT Device Wound Healing and Prevention | N/A | 2019-07-12 |
| Active Not Recruiting | Safety and Performance Study of the Legion Porous System in Total Knee Arthroplasty Total Knee Arthroplasty | — | 2019-05-22 |
| Completed | PMCF Study on PEEK Suture Anchors for Hip Indications Soft Tissue to Bone Fixation | — | 2019-05-10 |
| Completed | A Clinical Study to Evaluate the Safety and Efficacy of Q-Fix Trial in Chinese Patients Arthroscopy | N/A | 2019-04-12 |
| Completed | Safety and Performance of JOURNEY™ II Cruciate Retaining (CR) Total Knee System (TKS) Journey II CR Total Knee System | — | 2019-03-27 |
| Completed | Safety and Performance of PEEK Anchors in Extremities Medial or Lateral Instability Repairs/Reconstructions, Hallux Valgus Repairs, Achilles Tendon Repairs/Reconstructions | — | 2019-03-12 |
| Completed | A Clinical Study to Assess the Safety and Clinical Performance of a New Dressing (PICO7Y) in Breast Surgery Pa Oncoplastic Breast Surgery, Bilateral Surgery | N/A | 2019-03-08 |
| Completed | PMCF Study on PEEK Suture Anchors for Shoulder Indications Soft Tissue to Bone Fixation | — | 2019-02-14 |
| Terminated | A Safety Follow Up Study in Australian Subjects Implanted With the SMF Short Modular Femoral Stem Hip System Total Hip Arthroplasty (THA) | — | 2019-02-14 |
| Terminated | Treatment of Partial-Thickness Rotator Cuff Tears Arthroscopic Surgical Treatment of High-grade (>50%) Partialthickness | N/A | 2018-12-05 |
| Completed | Performance, Safety and Efficacy of PICO Device. Wound Heal | N/A | 2018-11-06 |
| Completed | Safety and Performance of Journey II XR Total Knee System Journey II XR Total Knee System | — | 2018-11-01 |
| Completed | Safety and Performance of the TFCC FastFix in the Wrist Suture Retention Device to Facilitate Triangular Fibrocartilage Complex (TFCC) Repair | — | 2018-09-28 |
| Terminated | Safety Study of Femoral Neck Fracture System Femoral Neck Fractures | N/A | 2018-09-10 |
| Completed | S&P of Q-Fix™ All-Suture Anchor System Bankart Lesion, Acetabular Labrum Tear, SLAP Lesion | — | 2018-08-31 |
| Active Not Recruiting | Safety and Performance Using Legion™ CR Oxinium and CoCr Femoral Implants Combined With Legion™/Genesis™ II XL Total Knee Arthroplasty | — | 2018-08-26 |
| Completed | Safety and Performance of the Journey™ II UNI Unicompartmental Knee System Non-inflammatory Degenerative Joint Disease (NIDJD) of the Knee | — | 2018-08-10 |
| Completed | Safety and Performance of Journey II BCS Total Knee System Patient Reported Outcome Measures Journey II BCS Total Knee System | — | 2018-07-19 |
| Enrolling By Invitation | A Multicenter, Post-Market Clinical Follow-up Study of Subjects With the REDAPT™ System Monolithic Sleeveless/ Hip Replacement | — | 2018-05-07 |
| Unknown | Journey™ UNI Post Market Clinical Follow-Up Non-inflammatory Degenerative Joint Disease | — | 2018-04-11 |
| Completed | R3 Delta Ceramic Acetabular System PAS U.S. Degenerative Joint Disease | — | 2018-02-07 |
| Completed | DURAFIBER Ag Post-Market Clinical Follow-Up Wounds and Injuries, Venous Leg Ulcer, Infection | N/A | 2017-12-12 |
| Completed | Navio With Total Knee Arthroplasty Total Knee Arthroplasty, Arthroplasty of Knee | — | 2017-11-13 |
| Completed | BIOSURE™ RG Knee Safety & Performance Study ACL Repair, Posterior Cruciate Ligament (PCL) Repair, Medial Collateral Ligament (MCL) | — | 2017-11-09 |
| Completed | Agili-C™ Implant Performance Evaluation Cartilage or Osteochondral Defects in the Knee, Up to Moderate Osteoarthritis | N/A | 2017-09-25 |
| Terminated | Long Term Follow-up of Integra® Cadence™ Total Ankle System in Primary Ankle Joint Replacement Degenerative Arthritis, Rheumatoid Arthritis, Traumatic Arthritis | — | 2017-09-18 |
| Suspended | Clinical Evaluation of Integra® Cadence™ Total Ankle System in Primary Ankle Joint Replacement (CADENCE) Rheumatoid Arthritis, Degenerative Arthritis, Post Traumatic Arthritis | — | 2017-08-24 |
| Terminated | Clinical Evaluation of the Integra® Titan™ Modular Shoulder System Generation 2.5 for Primary Shoulder Joint R Osteo Arthritis Shoulders, Traumatic Arthritis, Rheumatoid Arthritis | — | 2017-08-01 |
| Active Not Recruiting | JOURNEY II XR Safety and Effectiveness PMCF Rheumatoid Vasculitis With Rheumatoid Arthritis of Knee, Unilateral Post-Traumatic Osteoarthritis of Knee, Knee Osteoarthritis | — | 2017-07-28 |
| Completed | A Retrospective Study of the Navio Robotic-assisted Surgical System Surgical Robotics, Knee Replacement | — | 2017-07-10 |
| Active Not Recruiting | Ten Year Implant Survivorship of the ANTHEM™ PS Total Knee System Arthroplasty, Replacement, Knee | — | 2017-06-28 |
| Completed | Evaluation Of An Advanced Borderless Dressing Pressure Ulcer, Leg Ulcer, Diabetic Foot Ulcer | N/A | 2017-06-15 |
| Terminated | Clinical Evaluation of the TITAN™ Total Shoulder System Arthritis, Arthritis, Degenerative, Rheumatoid Arthritis | — | 2017-03-20 |
| Completed | Predictors of Early Success From Circumferential Compression STITCH Meniscal Repairs Knee Medial Meniscus Tears, Meniscus Lesion, Meniscus; Rupture, Bucket Handle | — | 2017-02-01 |
| Withdrawn | Comparison of Surgical Incision Complications in Patients Receiving PICO or Standard Care Following Colorectal Wounds and Injuries | N/A | 2017-01-01 |
| Completed | Journey II Bi-Cruciate Stabilized (BCS) Total Knee System Retrospective Study Total Knee Arthroplasty | — | 2016-12-30 |
| Withdrawn | Non-Comparative Study of Open Abdomen That Require the Use of Negative Pressure Wound Therapy (NPWT) for Tempo Abdomenal Wound Trauma | N/A | 2016-12-01 |
| Completed | ACTICOAT™ for the Treatment of Burns and Chronic Wounds Wounds and Injuries, Burns, Pressure Ulcer | N/A | 2016-11-01 |
| Completed | PyroTITAN Humeral Resurfacing Arthroplasty (HRA) Arthritis | — | 2016-10-01 |
| Terminated | Journey II BCS CMS Total Knee System Compared to Other PS Total Knee Systems in PT Setting Osteoarthritis, Degenerative Arthritis, Traumatic Arthritis | — | 2016-09-01 |
| Completed | Agili-CTM Implant Performance Evaluation in the Treatment of Osteoarthritis of the Great Toe Osteoarthritis of Multiple Joints of Ankle or Foot | N/A | 2016-08-10 |
| Terminated | Study of SANTYL® vs Hydrogel (SoloSite®) for Pressure Ulcers Pressure Ulcer | Phase 4 | 2016-08-01 |
| Withdrawn | Use of Santyl Within an Accountable Care Organization Pressure Ulcer, Foot Ulcer, Diabetic | Phase 4 | 2016-08-01 |
| Withdrawn | Managing Wounds With Allevyn Life in a Home Health Care Environment Wounds and Injuries | N/A | 2016-08-01 |
| Completed | Achilles Tendon Repair With Bioinductive Implant Tendinopathy | N/A | 2016-06-03 |
| Completed | Rotation Medical Bioinductive Implant Database Registry Rotator Cuff Tear | — | 2016-04-25 |
| Completed | Treatment of Wounds With a New Adhesive Foam Dressing Wounds and Injuries, Burns | N/A | 2016-03-01 |
| Terminated | REDAPT Retrospective-Prospective Modular Stem Study Arthroplasties, Hip Replacement | — | 2016-02-01 |
| Withdrawn | LEGION™ Revision Metal Hypersensitivity Study Total Knee Replacement Revision | N/A | 2016-01-01 |
| Completed | Use of Santyl in Diabetic Foot Ulcers Diabetic Foot, Foot Ulcer, Diabetic | Phase 4 | 2015-10-01 |
| Active Not Recruiting | JOURNEY™ II CR Total Knee System Osteoarthritis, Knee | — | 2015-09-01 |
| Active Not Recruiting | Post Market Clinical Follow Up of LEGION™ Primary TKS With VERILAST™ Degenerative Joint Disease | — | 2015-09-01 |
| Terminated | A Retro-prospective Study of Total Hip Arthroplasty With EMPERION Modular Primary Stem in Australian Centres ( Osteoarthritis, Hip, Arthritis, Degenerative | — | 2015-08-01 |
| Completed | Single-Use Negative Pressure Wound Therapy System vs. Traditional Negative Pressure Wound Therapy System (tNPW Venous Leg Ulcers, Diabetic Foot Ulcers | N/A | 2015-07-02 |
| Active Not Recruiting | LEGION Hinge Safety and Efficacy Study Knee Arthroplasty, Total | — | 2015-06-30 |
| Completed | The Clinical Efficacy of RENASYS TOUCH NPWT System in the Management of Acute, Sub-acute and Chronic Wounds Wound and Injuries, Surgical Wound Dehiscence | N/A | 2015-04-01 |
| Active Not Recruiting | OXINIUM◊ DH Total Hip Arthroplasty Pivotal Study Hip Osteoarthritis | — | 2015-01-01 |
| Withdrawn | REDAPT Revision System Study to Assess 5 Year Revision Rate & up to 10 Year Revision Rate and Safety and Effec Total Hip Arthroplasty (THA) | — | 2014-12-01 |
| Completed | Study of Suture Repair of Torn Meniscus in the Knee Meniscal Tear, Meniscus Tear | N/A | 2014-11-19 |
| Completed | BIOSURE™ HEALICOIL™ PK Bone In-growth Study Deficiency of Anterior Cruciate Ligament | — | 2014-09-12 |
| Terminated | TITAN™ Reverse Shoulder System Osteoarthritis of the Shoulder | — | 2014-09-01 |
| Completed | Post-Market Evaluation of the Rotation Medical Rotator Cuff System Partial Thickness Supraspinatus Tendon Tear, Full Thickness Supraspinatus Tendon Tear | N/A | 2014-08-20 |
| Terminated | A RCT to Compare the Effects of Two Wound Products on Biofilm Disruption in DFUs Diabetic Foot Ulcer | N/A | 2014-08-01 |
| Completed | Visionaire Health Economics Study Comparing Economic Outcomes Between Visionaire and Standard Instrumentation Osteoarthritis, Knee | N/A | 2014-07-09 |
| Completed | A RCT to Compare Performance of Two Foam Dressings on Patient Well-being Related Endpoints. Chronic Wounds | N/A | 2014-05-01 |
| Completed | Agili-C™ Implant Performance Evaluation in the Repair of Cartilage and Osteochondral Defects Cartilage or Osteochondral Defects in the Knee | N/A | 2014-05-01 |
| Terminated | A Pilot Study of the WoundWand™ Debridement Device on Infection Prevention Lower Leg Wound | N/A | 2014-03-04 |
| Terminated | Mechanical vs. Radiofrequency-Based Debridement in the Treatment of Articular Cartilage Lesions Chondral Lesion Plus Partial Medial Meniscectomy | N/A | 2013-03-08 |
| Completed | Pilot Study of the Use of ULTRABRAID PLUS SUTURE in the Repair of Tears of the Rotator Cuff Rotator Cuff Tear | N/A | 2013-02-01 |
| Terminated | Visionaire™ Versus Standard Instrumentation Safety and Efficacy in Total Knee Arthroplasty (TKA) Degenerative Arthritis of Knee | N/A | 2012-06-21 |
| Completed | PICO Breast Reduction Clinical Study Looking at Incision Healing Complications Delayed Healing | N/A | 2012-06-01 |
| Completed | Safety and Efficacy of the Journey II BCS Total Knee System Osteoarthritis, Knee | — | 2012-06-01 |
| Completed | Research Study to Compare the Addition of Topaz Micro Debridement to the Standard of Care Surgery Greater Trochanteric Pain Syndrome, Hip Pain Chronic | N/A | 2012-04-01 |
| Terminated | Trial of PICO Versus Standard Care in Chronic and Sub-acute Wounds Wounds | N/A | 2012-03-01 |
| Completed | Pilot Study Evaluating the Safety and Efficacy of a New Hard-on-Hard Total Hip Replacement System Arthritis, Degenerative | N/A | 2011-11-04 |
| Completed | Evaluation of the Agili-C Biphasic Implant in the Knee Joint Cartilage Diseases, Osteochondritis Dissecans | N/A | 2011-06-01 |
| Terminated | TRIGEN SURESHOT™ Distal Targeting System Study Femoral Shaft Fracture | N/A | 2011-04-01 |
| Terminated | Five and Ten Year Results of the CMK21 Hip System Osteoarthritis | — | 2010-12-01 |
| Completed | A Multi-center Outcomes Clinical Study of the PyroTITAN™ HRA Shoulder Implant in Humeral Head Resurfacing Arthritis | — | 2010-08-01 |
| Completed | VISIONAIRE™ Value Study Osteoarthritis of the Knee | — | 2010-04-01 |
| Completed | Clinical Outcome of Birmingham Hip Resurfacing (BHR) Using VISIONAIRE Femoral Alignment Guide Osteoarthritis | — | 2009-10-01 |
| Completed | R3® Acetabular System in Patients With Degenerative Hip Disease Osteoarthritis | — | 2009-10-01 |
| Completed | Mini Stem DEXA (Dual Energy X-ray Absorptiometry) Osteoarthritis, Hip | — | 2009-09-14 |
| Terminated | LEGION™ Primary Safety and Efficacy Osteo Arthritis Knee, Total Knee Replacement | N/A | 2009-09-09 |
| Completed | Mini Stem Radiostereometric Analysis Study Osteoarthritis, Hip | — | 2009-06-30 |
| Completed | POLARSTEM Cementless Hip Stem Osteoarthritis | — | 2009-03-01 |
| Terminated | Ascension PyroCarbon Radial Head Study Degenerative Arthritis, Radial Head Fracture, Rheumatoid Arthritis | N/A | 2009-01-01 |
| Terminated | Smith & Nephew's European Trufit Study Defect of Articular Cartilage | N/A | 2008-04-15 |
| Completed | Evaluation of the Use of EZCare/V1STA in the Management of Acute and Chronic Wounds Wounds | N/A | 2008-04-01 |
| Terminated | Knee Articular Cartilage Debridement in Conjunction With Partial Meniscectomy Torn Meniscus | Phase 4 | 2008-04-01 |
| Terminated | Clinical Outcome Following Total Hip Arthroplasty With the SMF Stem Joint Diseases | — | 2008-02-27 |
| Terminated | INTUIT Hip Fracture Outcome Study Unstable Intertrochanteric Hip Fractures | — | 2008-01-01 |
| Completed | Trial of Versajet Compared With Conventional Treatment in Acute and Chronic Wounds Surgical Wound Dehiscence | N/A | 2007-11-01 |
| Completed | Ankle Joint Replacement Outcomes Study Osteoarthritis, Rheumatoid Arthritis, Post-Traumatic Arthritis | — | 2007-10-31 |
| Completed | A Safety and Efficacy Study of the Birmingham Hip Resurfacing System Arthritis | — | 2006-10-06 |
| Completed | A Study of Patients Treated With the Journey Deuce Bicompartmental Knee System Osteoarthritis | — | 2006-09-01 |
| Completed | Study Comparing VERSAJET With Conventional Surgical Procedures in the Removal of Unhealthy Tissue From Lower L Diabetic Foot, Varicose Ulcer, Pressure Ulcer | Phase 4 | 2006-04-01 |
| Completed | Safety and Effectiveness Study of the Reflection Ceramic Acetabular System Osteoarthritis | N/A | 2004-12-01 |
| Terminated | Ascension® Post- Approval Study; PyroCarbon Metacarpophalangeal Total Joint Prosthesis Rheumatoid Arthritis, Systemic Lupus Erythematosus, Osteoarthritis | N/A | 2002-06-01 |