NCT02118558

Negative Pressure Wound Therapy -PREVENA in Prevention of Infections After Total Knee Arthroplasty (TKA)

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: —
• Sponsor: Hadassah Medical Organization · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This trial is a prospective, single center, unblinded, randomized, controlled study to assess the safety and efficacy of negative pressure wound therapy in preventing infections after TKA surgery . The study will enroll 316 patients that will undergo TKA. patients will be randomized to the treatment group and undergo the study intervention - (NPWT) The intervention will take place at the end of the surgery. The Patients that are randomized to the control group will receive standard treatment. Both groups will be assessed at two weeks and six weeks. period.

Conditions

• Total Knee Replacement

Interventions

Type	Name	Description
DEVICE	Negative Pressure Wound Therapy (NPWT)
DRUG	standard prophylactic therapy	administration of antibiotics before the first incision, keeping the surgery field sterile and performing several rinsing

Timeline

• Start date: 2014-06-01
• Primary completion: 2016-01-01
• Completion: 2017-01-01
• First posted: 2014-04-21
• Last updated: 2014-04-21