| Recruiting | Efficacy And Safety Evaluation of Glepaglutide in Treatment of SBS NCT07197944 | Zealand Pharma | Phase 3 |
| Not Yet Recruiting | Effect of Parenteral Support on FibroScan in Short Bowel Syndrome NCT07206004 | Rigshospitalet, Denmark | — |
| Enrolling By Invitation | Palliative Care Needs of Children With Rare Diseases and Their Families NCT06938542 | Children's National Research Institute | N/A |
| Recruiting | A Feasibility Study to Evaluate Safety and Probable Benefit of the Eclipse XL1 System for Distraction Enteroge NCT05535361 | Eclipse Regenesis, Inc. | N/A |
| Recruiting | A Study of Teduglutide in Chinese Adults With Short Bowel Syndrome NCT06973304 | Takeda | Phase 3 |
| Recruiting | Safety and Efficacy of Crofelemer in Adult Patients With Short Bowel Syndrome and Intestinal Failure (SBS-IF) NCT06904872 | Napo Therapeutics, S.p.A. | Phase 2 |
| Recruiting | Open-Label Pilot Study With Crofelemer in Patients With Short Bowel Syndrome NCT06326645 | Lindsey Russell, MD | EARLY_Phase 1 |
| Completed | Specific Dietary Fibers May Enhance Colonic Adaptation in Short Bowel Syndrome Through Microbial and Metabolic NCT07186608 | Jinling Hospital, China | N/A |
| Recruiting | SBS DISK- Creation of a Quality of Life Tool for Short Bowel Patients Compared With a Validated Quality of Lif NCT06771505 | Hospices Civils de Lyon | — |
| Recruiting | Efficacy and Safety of PJ009 in Patients With Short Bowel Syndrome Requiring Parenteral Nutrition NCT06512584 | Chongqing Peg-Bio Biopharm Co., Ltd. | Phase 3 |
| Completed | Level of Deprivation Assessment in a Population of Short-bowel Syndrome Patients With Intestinal Failure NCT06391762 | Central Hospital, Nancy, France | — |
| Completed | Antithrombotic Management of Acute Mesenteric Ischaemia NCT05706012 | Universitaire Ziekenhuizen KU Leuven | — |
| Terminated | MENDD Tolerance Assessment Study NCT06185088 | University of Michigan | N/A |
| Completed | A Study of PJ009 in Healthy Adult Volunteers NCT06523101 | Chongqing Peg-Bio Biopharm Co., Ltd. | Phase 1 |
| Recruiting | Absorption of Antibiotics With High Oral Bioavailability in Short-bowel Syndrome NCT05302531 | Central Hospital, Nancy, France | Phase 1 |
| Enrolling By Invitation | A 90 Day Observational Study as an Extension to the Phase 3,Open Labeled Exploratory Study of RELiZORB NCT05635747 | Boston Children's Hospital | — |
| Completed | Sarcopenia and Short Bowel Syndrome NCT05441345 | Assistance Publique - Hôpitaux de Paris | — |
| Recruiting | Efficacy Evaluation of UCB-MNCs in the Treatment of Refractory Neonatal Diseases NCT06427642 | Shandong Qilu Stem Cells Engineering Co., Ltd. | N/A |
| Recruiting | Phase 2 Study to Assess the Safety, PK, and PD of Sonefpeglutide (HM15912) in SBS-IF Subjects NCT04775706 | Hanmi Pharmaceutical Company Limited | Phase 2 |
| Completed | A Study With Teduglutide (Revestive®) in Adults With Short Bowl Syndrome NCT04883606 | Takeda | — |
| Completed | A Study of Teduglutide in Japanese Children With Short Bowel Syndrome Aged 4 Months or Older NCT05027308 | Takeda | Phase 3 |
| Completed | Study of NST-6179 in Healthy Subjects NCT05181085 | NorthSea Therapeutics B.V. | Phase 1 |
| Completed | Assessing Metabolic and Sleep Consequences of Overnight Home Parenteral Nutrition NCT04743960 | Massachusetts General Hospital | N/A |
| Completed | Improved Quality of Life in Children With Intestinal Failure NCT04981262 | Oslo University Hospital | N/A |
| Active Not Recruiting | A Study of Teduglutide in Japanese People With Short Bowel Syndrome NCT05023382 | Takeda | — |
| Completed | The Long-term Effect on Intestinal Absorption and Safety of Treatment With Glepaglutide in Patients With Short NCT04991311 | Zealand Pharma | Phase 3 |
| Active Not Recruiting | Open-label Extension Trial to Evaluate the Long-term Safety of Apraglutide in Short Bowel Syndrome. NCT05018286 | VectivBio AG | Phase 3 |
| Active Not Recruiting | Evaluation of Long Term Safety and Efficacy of Glepaglutide in Treatment of SBS - Extension Trial NCT04881825 | Zealand Pharma | Phase 3 |
| Terminated | VIBRANT Study of Vurolenatide in Adult Patients With Short Bowel Syndrome. NCT04988997 | 9 Meters Biopharma, Inc. | Phase 2 |
| Completed | Metabolic Balance Study of Apraglutide in Patients With Short Bowel Syndrome, Intestinal Failure (SBS-IF) and NCT04964986 | VectivBio AG | Phase 2 |
| Completed | Gastrointestinal Hormone Secretion, Intestinal Permeability and Short Bowel Syndrome NCT07235670 | Rigshospitalet, Denmark | N/A |
| Completed | Pediatric Teduglutide Registry NCT04832087 | Boston Children's Hospital | — |
| Completed | Trial to Evaluate Efficacy and Safety of Apraglutide in SBS-IF NCT04627025 | VectivBio AG | Phase 3 |
| Unknown | Pharmacokinetics of Apixaban in Patients With Short Bowel Syndrome Requiring Long Term Parenteral Nutrition NCT04344717 | Universitaire Ziekenhuizen KU Leuven | Phase 4 |
| Withdrawn | Use of Tocofersolan (Vedrop®) to Prevent or Treat Refractive Vitamin E Deficiency in Infants and Children NCT03582384 | Boston Children's Hospital | Phase 2 |
| Completed | A Study of Teduglutide (Revestive®) in Children, Teenagers and Adults With Short Bowel Disease NCT04877431 | Takeda | — |
| Unknown | Quality of Life in Patients With Short Bowel Syndrome Treated Without and With Teduglutide - a Prospective Nes NCT04733066 | Charite University, Berlin, Germany | — |
| Unknown | Proof of Concept Study in Patients With Short Bowel Syndrome NCT04379856 | 9 Meters Biopharma, Inc. | Phase 1 / Phase 2 |
| Completed | Plasma Oxalate in Patient With Short Bowel NCT04119765 | Hospices Civils de Lyon | — |
| Completed | Absorption of Peptides, Fluid, and Electrolytes in Patients With an Ileostomy NCT04141826 | Christian Hvas | N/A |
| Unknown | Pectin Use in Pediatric Intestinal Rehabilitation NCT04224168 | Le Bonheur Children's Hospital | N/A |
| Terminated | Efficacy, Safety and Tolerability of Enteric-Coated Cholestyramine Capsules for Adult Short Bowel Syndrome NCT04046328 | Pharmascience Inc. | Phase 2 |
| Active Not Recruiting | Evaluation of Long Term Safety and Efficacy of Glepaglutide in Treatment of SBS NCT03905707 | Zealand Pharma | Phase 3 |
| Completed | Bridging Intestinal Failure With Teduglutide - a Case Report NCT04916665 | Medical University of Vienna | — |
| Completed | Intralipid Versus SMOFlipid in HPN Patients NCT03773237 | Mayo Clinic | N/A |
| Recruiting | A 90 Day, Phase 3,Open Labeled Exploratory Study of RELiZORB NCT03530852 | Boston Children's Hospital | N/A |
| Completed | Efficacy And Safety Evaluation of Glepaglutide in Treatment of Short Bowel Syndrome (SBS) NCT03690206 | Zealand Pharma | Phase 3 |
| Completed | Malnutrition in Chronic Gastrointestinal Diseases, Cross-sectional Study NCT04474743 | University Medicine Greifswald | — |
| Completed | Safety, Efficacy and Pharmacokinetic Study of Teduglutide in Infants 4 to 12 Months of Age With Short Bowel Sy NCT03571516 | Shire | Phase 3 |
| Completed | An Extension Study of Teduglutide in Japanese Participants With Short Bowel Syndrome Who Completed 24 Weeks of NCT03596164 | Takeda | Phase 3 |
| Completed | Study of Teduglutide in Japanese Participants With Short Bowel Syndrome NCT03663582 | Shire | Phase 3 |
| Completed | Characterization of the Long-term Safety, Efficacy, and Pharmacodynamics Revestive® in the Management of Short NCT03562130 | Assistance Publique - Hôpitaux de Paris | Phase 4 |
| Completed | Safety, Efficacy, PD of FE203799 in Short Bowel Syndrome on Parenteral Support NCT03415594 | GlyPharma Therapeutics | Phase 1 / Phase 2 |
| Terminated | Effects of an Amino Acid Mixture on Gastrointestinal Function, Inflammation and Fluid Balance: A Pilot Study i NCT03451253 | Entrinsic Bioscience Inc. | N/A |
| Terminated | Effect of a Short Message Service Intervention on Patients With Short Bowel Syndrome NCT03419156 | St. Louis University | N/A |
| Completed | Sham Feeding Post-operative Infants NCT03350022 | Le Bonheur Children's Hospital | N/A |
| Withdrawn | Liraglutide on Decreasing Parenteral Support in Short Bowel Patients (SLIPS) NCT03371862 | Imperial College London | Phase 2 |
| Completed | A Study in Japanese Children With Short Bowel Syndrome Who Completed SHP633-302 NCT03268811 | Shire | Phase 3 |
| Terminated | Amino Acid-based Oral Rehydration Solution in Children With Short Bowel Syndrome NCT03105362 | Boston Children's Hospital | N/A |
| Unknown | ImpRovE underSTanding of Short bOwel syndRome in Latin-amErica NCT04976075 | La Fundacion Favaloro para la Investigacion y la Docencia Medica | — |
| Completed | Osmolality of Oral Supplements and Ileostomy Output NCT03348709 | University of Aarhus | N/A |
| Completed | Use of Pancreatic Enzymes in Short Bowel Syndrome NCT03097029 | Children's Hospital of Philadelphia | Phase 2 |
| Terminated | Safety and Efficacy Study in Infant With SBS NCT02865122 | Elgan Pharma Ltd. | Phase 2 / Phase 3 |
| Withdrawn | SMOFLipid in Patients Who Are Intralipid Intolerant NCT03054948 | Mayo Clinic | Phase 4 |
| Completed | Study in Japanese Pediatric Subjects With Short Bowel Syndrome (SBS) Who Are Dependent on Parenteral Support NCT02980666 | Shire | Phase 3 |
| Completed | Long-term Safety and Efficacy Study of Teduglutide in Pediatric Participants With Short Bowel Syndrome (SBS) NCT02954458 | Shire | Phase 3 |
| Completed | Probiotics in Short Bowel Syndrome NCT03980327 | British Columbia Children's Hospital | N/A |
| Completed | A Study to Monitor the Use of an Amino Acid-Based Infant Formula NCT02953223 | Société des Produits Nestlé (SPN) | — |
| Completed | Nonthyroidal Illness Syndrome in SBS NCT04450472 | Jinling Hospital, China | — |
| Completed | Long-term Study of Teduglutide in Pediatric Subjects With Short Bowel Syndrome Who Completed the TED-C13-003 S NCT02949362 | Shire | Phase 3 |
| Completed | Teen and Young Adult Connections for Support From Multidisciplinary Professionals & Peers NCT02987569 | University of Kansas Medical Center | N/A |
| Completed | Short Bowel Syndrome Research Study for Children Up To 17 Years of Age on Parenteral Nutrition NCT02682381 | Shire | Phase 3 |
| Completed | Teduglutide in Short Bowel Syndrome Patients NCT04857801 | Medical University of Vienna | — |
| Completed | A Phase 2 Trial Testing ZP1848 in Patients With SBS NCT02690025 | Zealand Pharma | Phase 2 |
| Completed | A Trial to Investigate the Effect of Different Supplements on Fluid and Sodium Status in Short Bowel NCT02686606 | London North West Healthcare NHS Trust | N/A |
| Terminated | The Use of DPP-4 Inhibitors in Short Bowel Syndrome NCT02653131 | Stanley Dudrick's Memorial Hospital | Phase 4 |
| Completed | Measurement of Body Composition by Air Displacement Plethysmography in Pediatric Intestinal Failure Patients NCT02561819 | Christopher Duggan | — |
| Completed | Intestinal Microbial Dysbiosis in Chinese Infants With Short Bowel Syndrome With Different Complications NCT02699320 | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | — |
| Completed | Compassionate Use of Omegaven in Children NCT02370251 | University of Oklahoma | Phase 2 / Phase 3 |
| Withdrawn | A Open Label Extension Study for Subjects That Complete Study MP-101-CL-001 NCT02246816 | Marathon Pharmaceuticals, LLC | Phase 3 |
| Completed | rtPA in in the Prevention of CVAD-Associated Thrombosis and Infection in Pediatric Patients With Short Bowel S NCT02355743 | Lynn Malec | Phase 4 |
| Completed | Study to Evaluate the Safety, Efficacy and Pharmacokinetics of Teduglutide in Japanese Subjects With PN-depend NCT02340819 | Shire | Phase 3 |
| Withdrawn | A Phase III Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Investigational Product MP-101 in NCT02242656 | Marathon Pharmaceuticals, LLC | Phase 3 |
| Terminated | Loperamide vs. Placebo's Effect on Ileostomy Output: A Clinical Randomized Blinded Cross-over Study NCT02266849 | Odense University Hospital | Phase 3 |
| Active Not Recruiting | Registry for Participants With Short Bowel Syndrome NCT01990040 | Shire | — |
| Completed | Comparison of Different Oral Rehydration Solutions NCT02142582 | Mayo Clinic | N/A |
| Completed | Short Bowel Syndrome and Teduglutide Versus Placebo NCT02099084 | Mayo Clinic | Phase 4 |
| Completed | A Pharmacokinetic, Safety, and Pharmacodynamic Study of Teduglutide in Pediatric Subjects With Short Bowel Syn NCT01952080 | Shire | Phase 3 |
| Completed | Treatment of Vitamin D Deficiency in Intestinal Rehabilitation Clinic Patients With a Portable Ultraviolet B L NCT01930539 | University of Nebraska | N/A |
| Completed | Infant & Toddler Short Gut Feeding Outcomes Study NCT01946503 | Children's Hospital Los Angeles | — |
| Withdrawn | Exenatide on GI Motor Function and Permeability in Short Bowel Syndrome NCT01818648 | Mayo Clinic | Phase 4 |
| Completed | Energy Metabolism in Patients With Short Bowel Syndrome NCT02113228 | University of Sao Paulo | — |
| Completed | The Preventative and Therapeutical Effect of Ursodeoxycholic Acid(UDCA) to Short Bowel Syndrome Patients NCT01974336 | Jinling Hospital, China | Phase 4 |
| Completed | Prescription Pattern of Adjuvant Drugs and Vitamins in Patients Undergoing Long-term Home Nutritional Support NCT01696656 | University of Sao Paulo | — |
| Completed | Home Parenteral Nutrition (HPN) Families' Mobile Distance Connections to Care Research NCT01900288 | University of Kansas Medical Center | N/A |
| Completed | A One-Year, Open-Label Study With Teduglutide for Subjects Who Completed Study CL0600-021 NCT01560403 | Shire | Phase 3 |
| Completed | Enteral Glutamine in Reducing Bloodstream Infections in Short Bowel Syndrome Infants NCT01576003 | Children's Hospital Medical Center, Cincinnati | N/A |
| Completed | Survival and PN Dependence in SBS Patients NCT06102668 | The First Affiliated Hospital of University of Science and Technology of China | — |
| Terminated | Safety and Dosing Study of Glucagon-like Peptide 2 (GLP-2) in Infants and Children With Intestinal Failure NCT01573286 | Alberta Children's Hospital | Phase 1 / Phase 2 |
| Completed | Elemental Formula in Neonates Post Small Bowel Resection: Improved Weaning From Total Parenteral Nutrition? NCT01891279 | The University of Texas Health Science Center, Houston | N/A |
| Withdrawn | Trial of 70% Ethanol Versus Heparin to Reduce the Rate of Central Line Infections in Children With Short Bowel NCT01263574 | Boston Children's Hospital | Phase 2 |
| Withdrawn | Investigational Study of Oral Fish Oil in Treating Parenteral Nutrition Associated Liver Disease NCT01191177 | Boston Children's Hospital | Phase 1 / Phase 2 |
| Unknown | Magnetic Resonance (MR) Enterography Assessment of Post Operative Small Bowel Length in Short Bowel Syndrome P NCT01183793 | Centre Hospitalier Universitaire de Nice | N/A |
| Recruiting | Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford NCT01793168 | Sanford Health | — |
| Withdrawn | Pharmacokinetics of Citalopram in Patients With Short Bowel Syndrome NCT00876226 | University of Nebraska | N/A |
| Completed | The Cholelithiasis in Adults With Short Bowel Syndrome NCT04867538 | Jinling Hospital, China | — |
| Completed | Early Provision of Enteral Microlipid and Fish Oil to Infants With Enterostomy NCT01306838 | Wake Forest University | EARLY_Phase 1 |
| Completed | Open-Label Study of Teduglutide for Subjects With PN-Dependent Short Bowel Syndrome (SBS) NCT00930644 | Shire | Phase 3 |
| Completed | Safety and Immunogenicity of Rotavirus Vaccine (RotaTeq(R)) in Infants With Short Bowel Syndrome NCT00767364 | Children's Hospital of Michigan | Phase 1 |
| Withdrawn | Evaluation of 70% Ethanol Lock Solution to Prevent Catheter Related Blood Stream Infections in Pediatric Patie NCT01409772 | University of Nebraska | — |
| Unknown | Efficacy and Safety of Omega-3 Lipid Therapy in Pediatric Patients With Parenteral Nutrition-Associated Liver NCT01739517 | Amarnath, Rathna, M.D. | Phase 2 |
| Unknown | Can SMOFlipid®, A Composite Parenteral Nutrition Lipid Emulsion, Prevent Progression Of Parenteral Nutrition A NCT00793195 | The Hospital for Sick Children | Phase 2 |
| Withdrawn | Fiber Use in Pediatric Short Bowel Syndrome NCT00922805 | Arkansas Children's Hospital Research Institute | N/A |
| Completed | Study of Teduglutide Effectiveness in Parenteral Nutrition (PN)-Dependent Short Bowel Syndrome (SBS) Subjects NCT00798967 | Shire | Phase 3 |
| Completed | rHGH and Intestinal Permeability in Intestinal Failure NCT01380366 | Northwestern University | Phase 4 |
| Completed | Cholestasis Reversal: Efficacy of IV Fish Oil NCT00910104 | Mark Puder | Phase 2 / Phase 3 |
| Completed | Evaluation of the Efficacy and Safety of Recombinant Human Growth Hormone (rhGH) in the Treatment of Children NCT00169637 | Hospices Civils de Lyon | Phase 3 |
| Completed | Plasma Determination of Glucagon-like Peptide 2 as a Predictor of Recovery in Adults With Acute Intestinal Fai NCT00180648 | Imperial College London | — |
| Completed | Safety and Efficacy Study of Teduglutide in Subjects With Short Bowel Syndrome Who Completed Protocol CL0600-0 NCT00172185 | Shire | Phase 3 |
| Completed | Mechanisms of Adaptation in Human Short Bowel Syndrome NCT00248573 | Emory University | — |
| Completed | Safety and Efficacy Study of Teduglutide in Subjects With Short Bowel Syndrome NCT00081458 | Shire | Phase 3 |
| Terminated | Evaluate the Efficacy and Safety Growth Hormone, Glutamine and Diet in Patients With Short Bowel Syndrome (SBS NCT00742157 | University of Nebraska | Phase 4 |
| Completed | Citrulline: A Plasmatic Marker to Assess and Monitor Small Bowel Crohn's Disease Patients NCT00138879 | St Mark's Hospital Foundation | — |
| Completed | Diet/Growth Factor Mechanisms of Gut Adaptation NCT00067860 | Emory University | Phase 2 |
| Approved For Marketing | Compassionate Use of Omegaven for Pediatric Patients With Parenteral Nutrition Associated Liver Disease NCT01297933 | Children's Hospital of Philadelphia | — |
| Unknown | Effect of the Enteric Hormone Glucagon-Like Peptide (GLP-2) on the Intestinal Blood Flow in Patients With Shor NCT00673751 | Glostrup University Hospital, Copenhagen | N/A |