NCT03105362

Amino Acid-based Oral Rehydration Solution in Children With Short Bowel Syndrome

Tolerability of an Amino Acid-based Oral Rehydration Solution in Children With Short Bowel Syndrome

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 4 (actual)
• Sponsor: Boston Children's Hospital · Academic / Other
• Sex: All
• Age: 1 Year – 17 Years
• Healthy volunteers: Not accepted

Summary

This study will assess the tolerability and palatability of an amino acid based oral rehydration solution (enterade®) compared to current oral rehydration solution among children with short bowel syndrome .

Detailed description

Patients with short bowel syndrome (SBS) have a critical reduction of the gut mass/function that is below the minimum needed to absorb nutrients and fluids required for adequate homeostasis. There are limited data regarding the optimal choice for oral rehydration in the setting of SBS that can maximize fluid absorption in the setting of diarrhea with limited intestinal absorptive surface area. The investigators propose a preliminary open label single center study assessing tolerability and palatability of enterade® ( an amino acid (AA) based oral rehydrating solution (ORS)) and compare to baseline. Eligible patients with SBS will participate in a 14-day trial monitoring and measuring tolerability and palatability of an AA-ORS, enterade®, in addition to their regular diet.

Conditions

• Short Bowel Syndrome

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Enterade® oral rehydration solution	Commercially available amino acid based oral rehydration solution

Timeline

• Start date: 2017-08-16
• Primary completion: 2018-01-20
• Completion: 2018-04-03
• First posted: 2017-04-07
• Last updated: 2020-02-24
• Results posted: 2019-12-17

Locations

1 site across 1 country: United States