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Active Not RecruitingNCT04881825

Evaluation of Long Term Safety and Efficacy of Glepaglutide in Treatment of SBS - Extension Trial

A 104-Week, Multicenter, Single-Arm, Long-Term, Phase 3 Extension Trial Investigating the Safety and Efficacy of Glepaglutide in Adult Patients With Short Bowel Syndrome (SBS) Completing the EASE SBS 2 Trial

Status
Active Not Recruiting
Phase
Phase 3
Study type
Interventional
Enrollment
129 (estimated)
Sponsor
Zealand Pharma · Industry
Sex
All
Age
18 Years – 90 Years
Healthy volunteers
Not accepted

Summary

This trial is an extension trial to EASE SBS 2. The study looks at whether glepaglutide is a safe treatment for participants with Short Bowel Syndrome (SBS), as well as how well effectiveness is maintained during long term treatment. Participants in this trial will receive glepaglutide as once-weekly injections under the skin (subcutaneous, s.c.) for approximately 2 years.

Conditions

Interventions

TypeNameDescription
DRUGGlepaglutideGlepaglutide will be delivered in a single-use autoinjector.

Timeline

Start date
2021-06-16
Primary completion
2026-04-01
Completion
2026-04-01
First posted
2021-05-11
Last updated
2026-02-02

Locations

19 sites across 8 countries: United States, Belgium, Denmark, France, Germany, Netherlands, Poland, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT04881825. Inclusion in this directory is not an endorsement.