NCT04867538

The Cholelithiasis in Adults With Short Bowel Syndrome

Prevalence, Risk Factors, and Complications of Cholelithiasis in Adults With Short Bowel Syndrome

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 345 (actual)
• Sponsor: Jinling Hospital, China · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

Short-term studies have shown that patients with short bowel syndrome (SBS) often develop cholestasis or cholelithiasis. In this retrospective cohort study, we aimed to define the incidence, risk factors, and clinical consequences of cholelithiasis in adults with SBS over an extended time period.

Detailed description

However, only limited data are available regarding cholelithiasis in patients with SBS. The prevalence of cholelithiasis in patients with SBS has been reported only in two studies. Furthermore, few studies have focused on identifying the risk factors for cholelithiasis in patients with SBS. Considering the marked improvements in medical care and nutrition support during the last 2 decades, the current incidence and risk factors for cholelithiasis in patients with SBS are unknown. The aim of the current study was to provide comprehensive, longitudinal, and long-term data on the incidence of symptomatic and asymptomatic cholelithiasis in a cohort of patients with SBS, in order to identify the prevalence, risk factors, and clinical consequences of cholelithiasis in patients with SBS to aid in the development of protective interventions.

Conditions

• Short Bowel Syndrome

Interventions

Type	Name	Description
OTHER	no intervention	No intervention

Timeline

• Start date: 2010-01-01
• Primary completion: 2019-12-31
• Completion: 2020-12-31
• First posted: 2021-04-30
• Last updated: 2021-04-30