Clinical Trials Directory

Trials / Conditions / MDS

MDS

137 registered clinical trials studyying MDS37 currently recruiting.

StatusTrialSponsorPhase
Not Yet RecruitingPacritinib With Aza for Upfront Myelodysplastic Syndrome
NCT07387354
Thomas Jefferson UniversityPhase 1 / Phase 2
RecruitingMT2025-35 Allogeneic Hematopoietic Stem Cell Transplantation Using Reduced Intensity Conditioning Treosulfan a
NCT07493538
Masonic Cancer Center, University of MinnesotaPhase 2
RecruitingQuality of Life-Guided Transfusion in Refractory MDS or AML
NCT07328191
Centre Hospitalier Universitaire de NiceN/A
RecruitingA Long Term Follow-up Study of TScan TCR-T Products
NCT06976736
TScan Therapeutics, Inc.
Not Yet RecruitingQH101 Cell Therapy Relapsed/Refractory(R/R) Acute Myeloid Leukemia(AML) and Myelodysplastic Syndromes(MDS)
NCT07131085
Anhui Provincial HospitalPhase 1
Not Yet RecruitingReduced Intensity Conditioning for MDS
NCT07085156
Ruijin HospitalPhase 2
RecruitingProspective Evaluation of Ivosidenib Maintenance Following Allogeneic Stem Cell Transplantation in Patients Wi
NCT06717958
Technische Universität DresdenPhase 2
RecruitingSafety of MT-401-OTS in Patients With Relapsed AML or MDS
NCT06552416
Marker Therapeutics, Inc.Phase 1
RecruitingMolecular Genetics Guide the Maintenance Therapy After Allogeneic Hematopoietic Stem Cell Transplantation
NCT06972641
Ruijin HospitalPhase 2 / Phase 3
RecruitingA Study of Oral Tetrahydrouridine-Decitabine in Relapsed or Refractory Myelodysplastic Syndromes (MDS)
NCT07006025
Treebough TherapiesPhase 1
RecruitingReplacing Bone Marrow Diagnostics With Peripheral Blood Analysis in Cytopenia Patients
NCT07081087
Weizmann Institute of Science
RecruitingComparison of ATLG and ATG for Immune Reconstitution After Allo-HSCT for Hematologic Malignancy
NCT06895538
Peking University First Hospital
RecruitingEganelisib as Monotherapy and in Combination With Cytarabine in Relapsed/Refractory AML
NCT06533761
Stelexis BioSciencesPhase 1
RecruitingA Phase 1 Study of CG009301 for Injection in Adult Subjects With Recurrent or Refractory Haematological Malign
NCT07347171
Cullgen (Shanghai),IncPhase 1
RecruitingOURA Ring Wearable Testing in MDS Patients: a Feasibility and Discovery Pilot Study
NCT06270771
Sunnybrook Health Sciences Centre
RecruitingBSB-1001 in Patients Undergoing HLA-Matched Allogenic Hematopoietic Stem Cell Transplant for AML, ALL or MDS
NCT06704152
BlueSphere Bio, IncPhase 1 / Phase 2
Not Yet RecruitingSelinexor Combined With Venetoclax Maintenance Therapy After Allo-HSCT
NCT06765928
Ruijin HospitalPhase 2
Enrolling By InvitationA Multicenter Study on the Treatment of MDS/MPN Overlap Syndrome With AZA or Rux Combined With Selinexor
NCT06664970
Peking Union Medical College HospitalPhase 2
Not Yet RecruitingA Study of HS-20106 to Treat Anemia Due to Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes
NCT06594965
Hansoh BioMedical R&D CompanyPhase 2
RecruitingCAR T-cell Therapy Directed to CD70 for Pediatric Patients With Hematological Malignancies
NCT06326463
St. Jude Children's Research HospitalPhase 1
RecruitingAssessment of Measurable Residual Disease in Allo-HSCT Using Digital Polymerase Chain Reaction
NCT06211166
Peking University People's Hospital
RecruitingCombination Salvage Therapy With Venetoclax and Decitabine in Relapsed/Refractory AML
NCT06156579
University Hospital TuebingenPhase 2
RecruitingHigh-Altitude Hematology Observation-Stem Cell Transplantation (HALO-SCT)
NCT07205523
Yigeng Cao,MD,PhD
RecruitingA Pilot Study to Evaluate the Feasibility of Post-Hematopoietic Stem Cell Transplant Prophylaxis With Decitabi
NCT05796570
Franziska WachterPhase 2
UnknownTo Evaluate the Phase I Clinical Study of XZB-0004 in Patients With AML and MDS
NCT05740917
Xuanzhu Biopharmaceutical Co., Ltd.Phase 1
UnknownClinical Efficacy and Mechanism of Yisui Granule in Treatment of Low and Medium Risk Myelodysplastic Syndrome
NCT05687513
Dongzhimen Hospital, BeijingEARLY_Phase 1
RecruitingA Phase 1 Study With LYT-200 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML), or With Relaps
NCT05829226
PureTechPhase 1
Active Not RecruitingVenetoclax in Patients With MDS or AML in Relapse After AHSCT
NCT05226455
Groupe Francophone des MyelodysplasiesPhase 1 / Phase 2
RecruitingTagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies
NCT05476770
Therapeutic Advances in Childhood Leukemia ConsortiumPhase 1
UnknownVenetoclax Plus RIC Regimen Allo-HSCT for Elderly Patients With High-risk Myeloid Malignancies
NCT05583175
Xianmin Song, MDPhase 2
Active Not RecruitingStudy Investigating Patient-Reported Outcomes in Lower-risk MDS Patients
NCT05582902
University of Leipzig
RecruitingStudy Evaluating Combination of Luspatercept in LR-MDS Without RS Having Failed or Being Ineligible to ESA
NCT05181735
Groupe Francophone des MyelodysplasiesPhase 1 / Phase 2
Active Not RecruitingA Phase II Study of Vibecotamab (XmAb14045) for MRD- Positive AML and MDS After Hypomethylating Agent Failure
NCT05285813
M.D. Anderson Cancer CenterPhase 2
Active Not RecruitingGvHD Prophylaxis in Unrelated Donor HCT: Randomized Trial Comparing PTCY Versus ATG
NCT05153226
DKMS gemeinnützige GmbHPhase 3
Active Not RecruitingFedratinib in Myelodysplastic /Myeloproliferative Neoplasms (MDS/MPNs) and Chronic Neutrophilic Leukemia (CNL)
NCT05177211
H. Lee Moffitt Cancer Center and Research InstitutePhase 2
CompletedSafety and Efficacy of Allogeneic NK Cell Infusions in Patients With Relapsed/Refractory AML and High Risk MDS
NCT04901416
Coeptis TherapeuticsPhase 1
UnknownPhase 2, Open-Label, Single Arm Study, With BST-236 in Adults With R/R AML or Higher-Risk MDS
NCT04749355
BioSight Ltd.Phase 2
UnknownHetrombopag for Low/Intermediate-1 Risk MDS With Thrombocytopenia
NCT05024877
Peking Union Medical College HospitalPhase 2 / Phase 3
TerminatedAPR-548 in Combination With Azacitidine for the Treatment of TP53 Myelodysplastic Syndromes (MDS)
NCT04638309
Aprea TherapeuticsPhase 1
RecruitingOptical Genome Mapping in Hematological Malignancies
NCT05009537
University Hospital, Brest
RecruitingPrecision Therapy Versus Standard Therapy in AML and MDS in Elderly
NCT05025098
University Hospital, AkershusPhase 2
CompletedASTX727 and Donor Lymphocyte Infusions After Allogenic Stem Cell Transplantation in Very High Risk MDS or AML
NCT04857645
Groupe Francophone des MyelodysplasiesPhase 2
UnknownAza With or Without ATRA in Newly Diagnosed Unfit AML or Intermediate,High or Very High Risk MDS
NCT05175508
The First Affiliated Hospital of Soochow UniversityPhase 2 / Phase 3
Active Not RecruitingA Study of CFI-400945 With or Without Azacitidine in Patients With AML, MDS or CMML
NCT04730258
Treadwell Therapeutics, IncPhase 1 / Phase 2
Active Not RecruitingPilot Study of CC 486 (Oral Azacitidine) Plus BSC as Maintenance After sc Azacitidine in Elderly HR-IPSS-R MDS
NCT04806906
University of FlorencePhase 2
UnknownPrognostic Value of Serum Erythropoietin Level,Ferritin Level and Fibrinogen in Adult Low Risk MDS
NCT04573686
Assiut University
UnknownA Study of APG-115 Alone or Combined With Azacitidine in Patients With AML, CMML, or MDS
NCT04358393
Ascentage Pharma Group Inc.Phase 1 / Phase 2
RecruitingNational Longitudinal Cohort of Hematological Diseases
NCT04645199
Institute of Hematology & Blood Diseases Hospital, China
RecruitingCord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders
NCT04644016
Memorial Sloan Kettering Cancer CenterPhase 2
Active Not RecruitingNKX101, Intravenous Allogeneic CAR NK Cells, in Adults With AML or MDS
NCT04623944
Nkarta, Inc.Phase 1
CompletedA Safety and Efficacy Study of SHR-1702 Monotherapy in Patients With Acute Myeloid Leukemia (AML) or Myelodysp
NCT04443751
Jiangsu HengRui Medicine Co., Ltd.Phase 1
Active Not RecruitingA Study Comparing Haploidentical Hematopoietic Stem Cell Transplantations (HSCTs) From Young Non-first-degree
NCT04547049
First Affiliated Hospital of Zhejiang UniversityPhase 3
SuspendedA Study Evaluating the Safety and Efficacy of IBI188 in Combination With AZA in Subjects With Newly Diagnosed
NCT04511975
Innovent Biologics (Suzhou) Co. Ltd.Phase 1
CompletedHaplo Peripheral Blood Sct In GVHD Prevention
NCT04473911
Zachariah Michael DeFilippPhase 1
RecruitingBMT-06: Study of Intensity Modulated Total Marrow Irradiation (IM-TMI)
NCT04187105
University of Illinois at ChicagoPhase 2
Active Not RecruitingEfficacy and Safety of HMAs Combined With Venetoclax Versus HMAs Alone in ND Int-and H-risk MDS or CMML
NCT07318662
Guangdong Provincial People's Hospital
WithdrawnCPX-351 in Patients Treated for Higher-risk Myelodysplastic Syndromes Experiencing Hypomethylating Agent Failu
NCT04109690
Yale UniversityPhase 1 / Phase 2
UnknownMutational Analysis as a Prognostic and Predictive Marker of Cardiovascular (CVD) Disease in Patients With Mye
NCT04110925
Sunnybrook Health Sciences CentreN/A
RecruitingComparison of Therapies Before Stem Cell Transplantation in Patients With Higher Risk MDS and Oligoblastic AML
NCT04061239
GWT-TUD GmbHPhase 2
CompletedCYC065 CDK Inhibitor and Venetoclax Study in Relapsed/Refractory AML or MDS
NCT04017546
Cyclacel Pharmaceuticals, Inc.Phase 1
UnknownStudy on High-risk MDS Patients Based on RNA-seq Technology
NCT03903055
Zhejiang Provincial Hospital of TCM
CompletedAPR-246 & Azacitidine for the Treatment of TP53 Mutant Myelodysplastic Syndromes (MDS)
NCT03745716
Aprea TherapeuticsPhase 3
UnknownChidamide Plus PTCy/Cyclosporine to Prevent GVHD After Myeloablative Conditioning, Matched PBSCT
NCT03336632
Sichuan UniversityPhase 2
UnknownStudy of APVO436 in Patients With AML or MDS
NCT03647800
Aptevo Research and Development LLCPhase 1
RecruitingFrailty Phenotype Assessments to Optimize Treatment Strategies for Older Patients With Hematologic Malignancie
NCT03680677
Abramson Cancer Center at Penn Medicine
CompletedDEPLETHINK - LymphoDEPLEtion and THerapeutic Immunotherapy With NKR-2
NCT03466320
Celyad Oncology SAPhase 1 / Phase 2
TerminatedSafety, Tolerability, Pharmacokinetics and Efficacy of AMG 397 in Subjects With Selected Relapsed or Refractor
NCT03465540
AmgenPhase 1
CompletedPevonedistat and Low Dose Cytarabine in Adult Patients With AML and MDS
NCT03459859
Justin Watts, MDPhase 1
UnknownMutant p53-based Personalized Trial Using Decitabine and Arsenic Trioxide on AML/MDS
NCT03855371
Ruijin HospitalPhase 1
CompletedHaploidentical Donor vs mMUD in Hematological Malignancies
NCT03275636
DKMS gemeinnützige GmbHPhase 2 / Phase 3
CompletedAscorbic Acid Levels in MDS, AML, and CMML Patients
NCT03526666
Van Andel Research Institute
WithdrawniCare3: Monitoring Circulating Cancer DNA After Chemotherapy in MDS and AML
NCT03138395
University of Florida
CompletedCX-01 Combined With Azacitidine in the Treatment of Relapsed or Refractory Myelodysplastic Syndrome and Acute
NCT02995655
Washington University School of MedicinePhase 1
RecruitingFamilial Investigations of Childhood Cancer Predisposition
NCT03050268
St. Jude Children's Research Hospital
CompletedA Study of Azacitidine in Myelodysplastic Syndrome (MDS) Associated to Systemic Auto-immune and Inflammatory D
NCT02985190
Groupe Francophone des MyelodysplasiesPhase 2
UnknownIndividual Molecular MRD Monitoring for MDS Patients After Allo-SCT
NCT02872662
Nordic MDS Group
CompletedAllogeneic Hematopoietic Stem Cell Transplantation in Patients With Myelodysplastic Syndrome Low Risk
NCT02757989
Groupe Francophone des MyelodysplasiesN/A
TerminatedControlled Study of Rigosertib Versus Physician's Choice of Treatment in MDS Patients After Failure of an HMA
NCT02562443
Traws Pharma, Inc.Phase 3
TerminatedA Study of E6201 for the Treatment of Advanced Hematologic Malignancies With FLT3 and/or Ras Mutations
NCT02418000
Spirita Oncology, LLCPhase 1 / Phase 2
CompletedNonmyeloablative Hematopoietic Cell Transplantation (HCT) for Patients With Hematologic Malignancies Using Rel
NCT02167958
Rafic Farah, MDPhase 1
CompletedA Study of LDE255 in Combination With Azacitidine for High Risk Myelodysplastic Syndrome Patients
NCT02323139
Groupe Francophone des MyelodysplasiesPhase 1
CompletedPharmacokinetic Guided Dose Escalation and Dose Confirmation With Oral Decitabine and Oral Cytidine Deaminase
NCT02103478
Astex Pharmaceuticals, Inc.Phase 1 / Phase 2
CompletedRandomized Phase III Study of Decitabine +/- Hydroxyurea (HY) Versus HY in Advanced Proliferative CMML
NCT02214407
Groupe Francophone des MyelodysplasiesPhase 3
CompletedUltra-Low Dose IL-2 Therapy as GVHD Prophylaxis in Haploidentical Allogeneic Stem Cell Transplantation
NCT02226861
National Heart, Lung, and Blood Institute (NHLBI)Phase 1
CompletedA Phase II Trial of SGI-110 in Patients With IPSS High and Int 2 Myelodysplastic Syndrome, Acute Myeloid Leuke
NCT02197676
Groupe Francophone des MyelodysplasiesPhase 2
CompletedStudy of FF-10501-01 in Patients With Relapsed or Refractory Hematological Malignancies
NCT02193958
Fujifilm Pharmaceuticals U.S.A., Inc.Phase 1 / Phase 2
CompletedAllo vs Hypomethylating/Best Supportive Care in MDS (BMTCTN1102)
NCT02016781
Medical College of WisconsinPhase 2
WithdrawnHaplo-identical SCT for High Risk (HR) Hematologic Malignancies w/Post-Transplant In-Vivo T-cell Depletion
NCT02053545
Ann & Robert H Lurie Children's Hospital of ChicagoPhase 1 / Phase 2
CompletedPhase 2 Study Adding Pracinostat to a Hypomethylating Agent (HMA) in Patients With MDS Who Failed to Respond t
NCT01993641
Helsinn Healthcare SAPhase 2
RecruitingAllogeneic Hematopoietic Stem Cell Transplant for GATA2 Mutations
NCT01861106
National Cancer Institute (NCI)Phase 2
UnknownA Study of Combined Deferasirox, Vitamin D and Azacytidine in High Risk MDS
NCT01718366
Groupe Francophone des MyelodysplasiesPhase 1 / Phase 2
CompletedDecitabine Combining Modified CAG Followed by HLA Haploidentical Peripheral Blood Mononuclear Cells Infusion f
NCT01690507
Chinese PLA General HospitalPhase 1 / Phase 2
TerminatedFLT-PET Imaging for MDS
NCT01535456
University of Wisconsin, MadisonN/A
CompletedEfficacy and Safety of Oral Rigosertib in Transfusion-dependent, Low or Int-1 or Trisomy 8 Int-2 Myelodysplast
NCT01584531
Traws Pharma, Inc.Phase 2
CompletedDarbepoetin Alfa in Patients With Anemic Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS)
NCT01362140
AmgenPhase 3
CompletedA Clinical Study of KRN321 in Adult Subjects With Myelodysplastic Syndrome
NCT01497145
Kyowa Kirin Co., Ltd.Phase 2
CompletedThe Effect of Blood Transfusion on Endothelial Function
NCT02161042
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
UnknownClAraC or FLAMSA Followed by Stem Cell Transplantation to Treat High Risk AML or Advanced MDS
NCT01423175
Hannover Medical SchoolPhase 2
UnknownBest Promising Drug Association With Azacitidine in Higher Risk Myelodysplastic Syndromes
NCT01342692
Assistance Publique - Hôpitaux de ParisPhase 2
CompletedSGI-110 in Participants With Myelodysplastic Syndromes (MDS) or Acute Myelogenous Leukemia (AML)
NCT01261312
Astex Pharmaceuticals, Inc.Phase 1 / Phase 2
TerminatedA Trial of Lenalidomide & Azacitidine in Low Risk Myelodysplastic Syndromes
NCT01379274
Rush University Medical CenterPhase 2
CompletedRandomized Study of ON 01910.Na in Refractory Myelodysplastic Syndrome Patients With Excess Blasts
NCT01241500
Traws Pharma, Inc.Phase 3
CompletedPhase 1 Study of TG02 Citrate in Patients With Advanced Hematological Malignancies
NCT01204164
Tragara Pharmaceuticals, Inc.Phase 1
CompletedNon-interventional Study With Azacitidin (Vidaza®)
NCT01192945
iOMEDICO AG
CompletedLenalidomide and Prednisone in Low and Int-1 Myelodysplastic Syndrome (MDS) Non 5q MDS
NCT01133275
H. Lee Moffitt Cancer Center and Research InstitutePhase 2
CompletedNon Interventional Study on Iron Toxicity After First Allo-transplant in MDS/CMML
NCT06267898
European Society for Blood and Marrow Transplantation
CompletedFludarabine and Cytarabine in Acute Myelogenous Leukemia (AML) and High-Risk Myelodysplastic Syndrome (MDS)
NCT01019317
M.D. Anderson Cancer CenterPhase 2
CompletedAllogeneic Stem Cell Transplant With Clofarabine, Busulfan and Antithymocyte Globulin (ATG) for Adult Patients
NCT00863148
Nantes University HospitalPhase 2
TerminatedPilot Trial of Targeted Immune-Depleting Chemotherapy and Reduced-Intensity Matched Unrelated Double Cord Bloo
NCT00973804
National Cancer Institute (NCI)Phase 1
CompletedPilot and Feasibility Study of Reduced-Intensity Hematopoietic Stem Cell Transplant for MonoMAC
NCT00923364
National Cancer Institute (NCI)Phase 2
CompletedControlled Study of Post-transplant Azacitidine for Prevention of Acute Myelogenous Leukemia and Myelodysplast
NCT00887068
M.D. Anderson Cancer CenterPhase 3
CompletedSTA-9090 for Treatment of AML, CML, MDS and Myeloproliferative Disorders
NCT00858572
Synta Pharmaceuticals Corp.Phase 1
RecruitingGlobal Registry and Natural History Study for Mitochondrial Disorders
NCT05554835
LMU Klinikum
CompletedUmbilical Cord Blood Transplant for Hematological Malignancies
NCT00891592
University of PennsylvaniaPhase 1
CompletedSafety Study of Bone Marrow Transplant Using Mismatched Tissue Followed by Chemotherapy
NCT00796562
Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsPhase 2
CompletedPharmacokinetics and Safety Study of Azacitidine in Cancer Patients With and Without Impaired Renal Function
NCT00652626
CelgenePhase 1
UnknownFeasibility and Efficacy Study of Conditioning Regimen for Allogeneic Hematopoietic Cell Transplantation (HCT)
NCT00815568
Samsung Medical CenterPhase 2
CompletedRomiplostim Treatment of Thrombocytopenia in Subjects With Low or Intermediate-1 Risk Myelodysplastic Syndrome
NCT00614523
AmgenPhase 2
TerminatedA Dose Range Finding Study of Lenalidomide in Non-5q Chromosome Deletion in Low and Intermediate Risk Myelodys
NCT00699842
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityPhase 1 / Phase 2
CompletedEvaluation of Formin Gene Status and Expression in Myeloproliferative and Myelodysplastic Disorders
NCT00687414
Corewell Health West
CompletedSafety Study of IL-7 in Recipients of a Hemopoietic Stem Cell Transplant Peripheral Blood Stem Cell Transplant
NCT00684008
Cytheris, Inc.Phase 1
CompletedLenalidomide in High-risk MDS and AML With Del(5q) or Monosomy 5
NCT00761449
Nordic MDS GroupPhase 2
CompletedPhase I Study of Gimatecan in Patients With Myelodysplastic Syndromes
NCT00493571
M.D. Anderson Cancer CenterPhase 1
TerminatedMyeloablative Allogeneic Stem Cell Transplantation Using a Naive T-Cell Depleted Peripheral Blood Stem Cell Gr
NCT00814983
Duke UniversityPhase 1 / Phase 2
CompletedEvaluating the Safety of Long Term Dosing of Romiplostim (Formerly AMG 531) in Thrombocytopenic Subjects With
NCT00472290
AmgenN/A
CompletedA Phase I Study of AC220 in Patients With Relapsed/Refractory Acute Myeloid Leukemia Regardless of FLT3 Status
NCT00462761
Daiichi SankyoPhase 1
CompletedDetermination of Safe and Effective Dose of Romiplostim (AMG 531) in Subjects With Myelodysplastic Syndrome (M
NCT00321711
AmgenPhase 2
TerminatedVelcade in Myelodysplastic Syndrome - Pilot Study
NCT00440076
Gruppo Italiano Malattie EMatologiche dell'AdultoPhase 2
CompletedDetermination of Safe Dose of Romiplostim (AMG 531) in Patients With Myelodysplastic Syndromes (MDS)
NCT00303472
AmgenPhase 2
CompletedUnrelated Umbilical Cord Blood Transplantation Augmented With ALDHbr Umbilical Cord Blood Cells
NCT00692926
Joanne Kurtzberg, MDPhase 1
CompletedMyeloablative Umbilical Cord Blood Transplantation in Hematological Diseases
NCT00309842
Masonic Cancer Center, University of MinnesotaPhase 2
TerminatedStem Cell Transplant for Hematological Malignancy
NCT00176930
Masonic Cancer Center, University of MinnesotaN/A
CompletedAllogeneic Transplantation From Related Haploidentical Donors
NCT00185692
Stanford UniversityPhase 2
TerminatedStem Cell Transplantation for Hematological Malignancies
NCT00176839
Masonic Cancer Center, University of MinnesotaPhase 2 / Phase 3
CompletedNonmyeloablative Allo SCT for the Treatment of Hematologic Disorders
NCT00636909
Beth Israel Deaconess Medical CenterPhase 2
CompletedGanciclovir by Infusion and by Mouth in Treating Patients With Cytomegalovirus After Donor Bone Marrow Transpl
NCT00530218
City of Hope Medical CenterPhase 2
CompletedDonor Lymphocyte Infusion (DLI) for Relapsed (Post Transplant) Leukemia
NCT00167167
Masonic Cancer Center, University of MinnesotaN/A