| Not Yet Recruiting | Heterozygous Individuals for AGXT and Kidney Stones NCT04430426 | University of Alabama at Birmingham | N/A |
| Not Yet Recruiting | Comparing Alkalinizing Agents Efficacy on Stone Risk in Patients on a Metabolically Controlled Diet NCT04651088 | University of Texas Southwestern Medical Center | EARLY_Phase 1 |
| Not Yet Recruiting | Prospective Multi-center Study Comparing Pulsed Tm:YAG Laser to Pulse Modulated Holmium Laser in the Treatment NCT07516106 | NYU Langone Health | N/A |
| Recruiting | Oxalate and Citrate in Humans - Response to Citrate NCT06944223 | University of Chicago | N/A |
| Recruiting | Access Sheath and Stent Trial NCT07297953 | University of Michigan | N/A |
| Not Yet Recruiting | HoYAG vs TFL in miniPCNL With ClearPetra NCT07087977 | University of Kansas Medical Center | N/A |
| Recruiting | A Single-Center Clinical Study on the Efficacy and Safety of VISOR NCT07071948 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Completed | Research on Early Warning and Diagnosis & Treatment Pathway for Micro Kidney Stones NCT07350369 | Xijing Hospital | — |
| Recruiting | ClearPetra™ Vacuum-assisted Ureteral Access Sheath vs Traditional Approach NCT06547632 | University of Kansas Medical Center | N/A |
| Withdrawn | Trial of Efficacy of the RetroPerc Device NCT05022537 | The University of Texas Health Science Center, Houston | N/A |
| Withdrawn | The Interplay Between Oxalate, Immunity and Infection NCT04605055 | University of Alabama at Birmingham | N/A |
| Not Yet Recruiting | Trial to Assess the Efficacy of EMPAgliflozin and Personalized Dietary Counseling for Kidney STONE Prevention NCT06653738 | Insel Gruppe AG, University Hospital Bern | Phase 3 |
| Not Yet Recruiting | A Novel Ureteric Stent in Kidney Stone Patients and Oncology Patients Compared to a Conventional JJ Stent NCT06815120 | University of Southampton | N/A |
| Enrolling By Invitation | Follow-Up of Ureteral Stones ≤4 mm NCT07176026 | Region Skane | — |
| Recruiting | Evaluation of the LithoVue Elite Ureteroscope With Intra-Renal Pressure Monitoring Technology: Examination of NCT06576661 | University of Kansas Medical Center | N/A |
| Recruiting | Effect of a DASH-Style Diet on Urinary Risk Factors for Kidney Stone Disease NCT06210009 | University of Alabama at Birmingham | N/A |
| Enrolling By Invitation | Meditation Effects on Discomfort, Pain InTerference, and AnxieTy After urEteroscopy NCT06783946 | Children's Hospital of Philadelphia | N/A |
| Withdrawn | The RELIEF™ Ureteral Stent Randomized Controlled Trial NCT06720740 | University of California, San Diego | N/A |
| Recruiting | Outcomes of Using FANS With FURS in TTT of Lower Calyceal Stones. NCT07238803 | Zagazig University | N/A |
| Recruiting | Indapamide and Chlorthalidone to Reduce Urine Supersaturation for Kidney Stone Prevention NCT06111885 | Insel Gruppe AG, University Hospital Bern | Phase 2 |
| Active Not Recruiting | Evaluate the Safety and Effectiveness of Steerable Ureteroscopic Renal Evacuation (SURE) Using the CVAC® Syste NCT06615713 | Calyxo, Inc. | N/A |
| Completed | Flexible Ureteroscopy With Tip-bendable Suction Ureteral Access Sheath Versus Mini-Percutaneous Nephrolithotom NCT06526390 | The First Affiliated Hospital of Guangzhou Medical University | N/A |
| Recruiting | Comparison of the Efficacy of Flexible Ureteroscope and Percutaneous Nephroscopic Surgery in the Treatment of NCT06507176 | The First Hospital of Jilin University | N/A |
| Recruiting | Kidney Stone Inflammation NCT06436235 | University of Chicago | — |
| Active Not Recruiting | Radiomics and Image Segmentation of Urinary Stones by Artificial Intelligence NCT06412900 | Oslo University Hospital | — |
| Recruiting | Gut Oxalate Absorption in Calcium Oxalate Stone Disease NCT06331546 | University of Alabama at Birmingham | N/A |
| Recruiting | O. Formigenes Colonization in Calcium Oxalate Kidney Stone Disease NCT06330246 | University of Alabama at Birmingham | N/A |
| Active Not Recruiting | A Retrospective, Multi-center Real-world Study of Steerable Ureteroscopic Renal Evacuation (SURE) Procedure Wi NCT07225933 | Calyxo, Inc. | — |
| Unknown | Thulium Fiber Laser Prospective Trial NCT05814133 | Centre hospitalier de l'Université de Montréal (CHUM) | N/A |
| Completed | Our Stone Fixation Technique to Improve Efficiency and Results of Peumatic Lithotripsy in Suction Mini-PCNL. NCT07328659 | Yasser Gamil Elnagar | N/A |
| Completed | Dual-process Mechanisms of Action for sipIT Intervention Effects in Patients With Urolithiasis NCT06269783 | University of Michigan | N/A |
| Recruiting | Impact of Forced Diuresis on the Residual Fragment Rate After Flexible Ureteroscopy for Destruction of Kidney NCT05916963 | University Hospital, Tours | Phase 3 |
| Completed | Intrarenal Pressure Monitoring Via Flexible and Navigable Suction Ureteral Access Sheath in Retrograde Intrare NCT06729801 | The First Affiliated Hospital of Guangzhou Medical University | N/A |
| Recruiting | Treatment Optimization and Nephrolithiasis Recurrence Prevention With Interdisciplinary Care NCT06367894 | Agnieszka Pozdzik | — |
| Unknown | Comparing Efficacy and Complication Between Prone Versus Prone-Flexed Position for Percutaneous Nephrolithotom NCT06624306 | Fayoum University Hospital | N/A |
| Unknown | Thulium Fiber Laser vs. Holmium:YAG Laser for the Ureteroscopic Treatment of Patients With Urinary Stone Disea NCT06306222 | IRCCS San Raffaele | N/A |
| Active Not Recruiting | SOUND Pivotal Trial - (Sonomotion stOne comminUtion resoNance ultrasounD) NCT05701098 | SonoMotion | N/A |
| Unknown | RIRS With Tip Flexible Pressure-controlling Ureteral Access Sheath Versus Mini PCNLfor Kidney Stones NCT06209931 | The Affiliated Ganzhou Hospital of Nanchang University | — |
| Withdrawn | A Study of BMN 255 in Participants With Non-Alcoholic Fatty Liver Disease And Hyperoxaluria NCT06138327 | BioMarin Pharmaceutical | Phase 1 |
| Recruiting | Neutrophil Extracellular Traps (NET's) in Prevalent Kidney Stone NCT06412822 | Brugmann University Hospital | — |
| Completed | Infection Control Measures for Patients Undergoing Percutaneous Nephrolithotomy NCT06437379 | Assiut University | N/A |
| Completed | Can Shear Wave Elastography Predict the Success of ESWL: a Prospective Study NCT05995652 | Abdelrahim Elsherbiny | — |
| Recruiting | Randomized Controlled Trial of Miniaturized Percutaneous Nephrolithotomy With Vacuum-Assisted Access Sheaths V NCT05993546 | The Cleveland Clinic | N/A |
| Completed | Tip Bendable Suction Ureteral Access Sheath vs. Traditional Ureteral Access Sheath in Retrograde Intrarenal St NCT05952635 | The First Affiliated Hospital of Guangzhou Medical University | N/A |
| Recruiting | Ureteroscopy With High-powered Holmium:Yag Laser Lithotripsy With and Moses On or Moses Off NCT06346483 | Northwestern University | N/A |
| Completed | Evaluation of Emergency Computed Tomography in Suspected Renal Colic. This is an Observational Retrospective S NCT06805149 | Region Skane | — |
| Withdrawn | LithoVue Elite Registry NCT05201456 | Boston Scientific Corporation | — |
| Completed | Erector Spinae Plane Block for Uncomplicated Renal Colic NCT05625802 | University of Michigan | Phase 2 |
| Recruiting | GI Oxalate Absorption NCT05356000 | University of Chicago | N/A |
| Recruiting | Prospective Evaluation of the LithoVue Elite Ureteroscope NCT04900688 | Centre hospitalier de l'Université de Montréal (CHUM) | N/A |
| Withdrawn | Research Project: Pilot Study on Oral Urea Use in Patients at High Risk of Kidney Stone Recurrence NCT04727606 | Centre hospitalier de l'Université de Montréal (CHUM) | Phase 2 |
| Unknown | Percutaneous Nephroscopic Treatment of Parapelvic Cysts NCT05504512 | Xiangya Hospital of Central South University | — |
| Recruiting | Oxalate and Citrate NCT05334979 | University of Chicago | N/A |
| Unknown | Evaluation of the Efficacy and Safety of Unimodal Bilateral Flexible Ureteroscopy. NCT05591716 | St. Petersburg State Pavlov Medical University | N/A |
| Enrolling By Invitation | Short Interval Versus Long Interval Repeated Extracorporeal Shockwave Lithotripsy (ESWL) for 8-15 mm Renal Sto NCT07421843 | Region Skane | N/A |
| Unknown | Clinical Outcomes and Healthcare Economics of SOLTIVE Compared to Ho:YAG Laser in Urolithiasis NCT04997668 | University of Kansas Medical Center | N/A |
| Recruiting | Thulium Fiber Laser (TFL) Versus Holmium MOSES Laser for Ureteroscopic Management of Kidney Stones NCT05598645 | Thunder Bay Regional Health Research Institute | N/A |
| Active Not Recruiting | Potassium Citrate and Crystal Light Lemonade NCT05389995 | Northwestern University | N/A |
| Completed | Evaluating the Vitamin K2 Status of Calcium-based Stone Formers NCT05081960 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | — |
| Active Not Recruiting | Reducing Opioid Prescription After Kidney Stone Removal Surgery NCT05353478 | Mayo Clinic | — |
| Recruiting | Modified Supine vs Prone Position Pnl NCT05379894 | Assiut University | — |
| Completed | Standard vs Mini-PCNL for the Treatment of Stone Disease NCT04069013 | The Cleveland Clinic | N/A |
| Completed | Predictors of Readmission in Patients Undergoing PNL NCT05852483 | Assiut University | — |
| Unknown | Is it Safe to Advance a Guidewire Through a Previously Placed Double j Stent? NCT05265936 | Ankara Training and Research Hospital | N/A |
| Unknown | A Novel Method for Retrograde Intrarenal Surgery (RIRS) NCT05202158 | Ankara Training and Research Hospital | N/A |
| Completed | Assessment of Endogenous Oxalate Synthesis NCT05229952 | University of Alabama at Birmingham | N/A |
| Unknown | A RCT to Evaluate the Efficacy and Safety of Automated Needle Targeting (ANT-X) System Compared to Traditional NCT05213702 | University of Malaya | N/A |
| Active Not Recruiting | Effect of Weight Loss on Urinary Oxalate Excretion in Obese Calcium Oxalate Kidney Stone Formers NCT04633811 | University of Alabama at Birmingham | N/A |
| Recruiting | Oxalate Formation From Ascorbic Acid NCT04603898 | University of Alabama at Birmingham | N/A |
| Withdrawn | The Impact of Nutritional Service in the Stone Clinic on the Patient Urine Collection Results NCT04545528 | Carmel Medical Center | — |
| Active Not Recruiting | Influence of Obesity on Oxalate Metabolism and Handling in Calcium Oxalate Stone Formers NCT04333745 | University of Alabama at Birmingham | N/A |
| Completed | Impact of the SGLT2 Inhibitor Empagliflozin on Urinary Supersaturations in Kidney Stone Formers NCT04911660 | Insel Gruppe AG, University Hospital Bern | Phase 2 |
| Recruiting | High Powered Stone Dusting vs. Fragmentation and Basketing at Time of Ureteroscopy NCT05006937 | Northwestern University | N/A |
| Completed | Comparison of Laser Lithotripsy With and Without Steerable Ureteroscopic Renal Evacuation (SURE) NCT04519294 | Calyxo, Inc. | N/A |
| Completed | The Newly Reported (0-90°) Versus (0-30°) Biplanar Fluoroscopic Puncture Technique in PCNL NCT04557722 | Menoufia University | N/A |
| Completed | Anesthesia Type on Percutaneous Nephrolithotomy in Aging Male NCT05431049 | Sedat Önen | — |
| Active Not Recruiting | Dietary Oxalate and Innate Immunity in Kidney Stone Disease NCT04051346 | University of Alabama at Birmingham | N/A |
| Withdrawn | Software Application for Low-Sodium Diet Trial (SALT) NCT04438551 | University of Rochester | N/A |
| Recruiting | Comparison of Imaging Quality Between Spectral Photon Counting Computed Tomography (SPCCT) and Dual Energy Com NCT04328181 | Hospices Civils de Lyon | N/A |
| Recruiting | Prediction of Recurrence and Complications of Nephrolithiasis Using a Precision Medicine Approach NCT05237063 | Centre Hospitalier Universitaire, Amiens | N/A |
| Unknown | Ureteral Stenting After Retrograde Intrarenal Surgery for Renal Stones NCT05738304 | Al-Azhar University | N/A |
| Completed | Noninvasive Electrical Stimulator as a Pain Control Treatment Post-ureteroscopy NCT05153629 | Stanford University | N/A |
| Completed | MIP Versus PCNL for Kidney Stone Disease NCT04767919 | University of California, San Diego | N/A |
| Completed | The Performance of the SOLTIVE Laser System for Laser Lithotripsy in Kidney or Ureteral Stones NCT04556201 | Olympus Corporation of the Americas | N/A |
| Unknown | Comparison of Efficacy of Intercostal Nerve Block vs Peritract Infiltration With 0.25% Bupivacaine in PCNL NCT04835922 | Tribhuvan University Teaching Hospital, Institute Of Medicine. | N/A |
| Unknown | Fluoroscopic Guided vs US-guided Percutaneous Nephrolithotripsy for the Treatment of Stone Disease NCT04606758 | Astana Medical University | N/A |
| Completed | Mini-PNCL vs fURS in Management of Nephrolithiasis NCT04389853 | Thunder Bay Regional Health Research Institute | N/A |
| Completed | Outcomes in Lower Pole Kidney Stone Management Using Mini-PCNL Compared With Retrograde Intra Renal Surgery NCT05714423 | Services Hospital, Lahore | N/A |
| Unknown | Holmium Vs Trilogy Kidney Stones GUY's 1-2 NCT04559321 | Hospital Regional de Alta Especialidad del Bajio | Phase 3 |
| Completed | Asymptomatic Renal Calculi in Recurrent Urinary Tract Infections NCT04495699 | Vanderbilt University Medical Center | — |
| Completed | Perioperative Pregabalin in Ureteroscopy NCT04122196 | University of Missouri-Columbia | Phase 2 / Phase 3 |
| Unknown | A Prospective Observational Comparison of SMP and ESWL for the Treatment of Renal Stones ≥20 mm in Children (I NCT04317443 | The International Alliance of Urolithiasis | — |
| Unknown | CT-Ultrasound Fusion in Guiding PCNL Puncture NCT04645472 | Zhenyu Wu | — |
| Completed | Pediatric KIDney Stone (PKIDS) Care Improvement Network NCT04285658 | Children's Hospital of Philadelphia | — |
| Unknown | Comparison of SP TFL and Ho:YAG for RIRS Using 145 µm and 200 µm Fibers NCT04346485 | I.M. Sechenov First Moscow State Medical University | N/A |
| Terminated | Regional Erector Spinae Analgesic Block vs Standard of Care Undergoing Percutaneous Nephrolithotomy NCT04663269 | Indiana University | Phase 4 |
| Completed | Antibiotic Selection Using Next Generation Sequencing vs Urine Culture NCT04404855 | The University of Texas Health Science Center at San Antonio | N/A |
| Completed | Shared Decision-Making for the Promotion of Patient-Centered Imaging in the ED: Suspected Kidney Stones NCT04234035 | Baystate Medical Center | N/A |
| Completed | Metabolic Risk Factors and Stones Composition in Adult Kidney Stone Formers NCT04243772 | Agnieszka Pozdzik | — |
| Completed | Opioid Free Management After Ureteroscopy NCT03872843 | Wake Forest University Health Sciences | Phase 4 |
| Completed | Evaluation of Infection in Obstructing Urolithiasis NCT04332861 | University of Texas Southwestern Medical Center | — |
| Completed | Effectiveness of Urinary Alkalinizing Agents on Kidney Stone Risk NCT04095975 | University of Wisconsin, Madison | Phase 4 |
| Completed | Impact of Acute Computed Tomography on Treatment Decisions and Time to Intervention in Renal Colic NCT06535711 | Region Skane | — |
| Completed | Comparison of Lithotripsy Urolithiasis Machines NCT04069338 | The Cleveland Clinic | N/A |
| Active Not Recruiting | Influence of Obesity on Endogenous Oxalate Synthesis NCT03704350 | University of Alabama at Birmingham | N/A |
| Withdrawn | Long Pulse Versus Short Pulse Laser Dusting for Renal Stones NCT03608098 | Wake Forest University Health Sciences | N/A |
| Unknown | Effects of Abdominal Cushion on PCNL in Prone Position NCT03797027 | The First Affiliated Hospital of Guangzhou Medical University | N/A |
| Unknown | Magnetic Ureteral Stent Symptoms - a Comparison to Standard Ureteral Stent as Perceived By the Patient (MAGUSS NCT03257306 | Turku University Hospital | N/A |
| Completed | Evaluation of Pain Before and After Removal of Non-obstructive Kidney Stones NCT03657667 | Centre hospitalier de l'Université de Montréal (CHUM) | N/A |
| Completed | Robotic-assisted Percutaneous Access NCT04435132 | NDR Medical Technology Pte Ltd | N/A |
| Completed | Protein Kinase 2 (HIPK2) Polymorphisms on rs2058265, rs6464214, and rs7456421 NCT04804436 | Saglik Bilimleri Universitesi | N/A |
| Recruiting | NSAIDs Stent Study NCT03638999 | Washington University School of Medicine | EARLY_Phase 1 |
| Unknown | LithoVue Single Use Disposable Ureteroscope NCT03419091 | University of British Columbia | N/A |
| Completed | SEARCH FOR OPTIMAL ANAESTHESIA IN RETROGRADE INTRARENAL SURGERY NCT03999255 | St. Petersburg State Pavlov Medical University | N/A |
| Terminated | Effect of Dietary Sodium and Potassium Citrate on Renal Mineral Handling NCT03281928 | University of Chicago | N/A |
| Completed | Toradol to Reduce Ureteroscopic Symptoms Trial NCT03111381 | Yale University | Phase 2 |
| Completed | A Retrospective and Prospective Cohort Study of the 21-day Fasting-like Diet in Patients With Metabolic and Au NCT03193177 | Tsinghua University | — |
| Unknown | Investigate the Renal Movement by Single Lung Ventilation in Patients Administered RIRS for Kidney Stones. NCT03060837 | Kahramanmaras Sutcu Imam University | N/A |
| Active Not Recruiting | Dietary Oxalate and Immune Cell Function NCT03877276 | University of Alabama at Birmingham | N/A |
| Completed | Ultrasound-guided Transmuscular Quadratus Lumborum Block for Percutaneous Nephrolithotomy NCT02818140 | Zealand University Hospital | Phase 4 |
| Completed | Are the Stone Density and Location Useful Parameters for Small Kidney Stones? NCT03503539 | Abant Izzet Baysal University | N/A |
| Completed | Comparing Pneumatic Versus Ultra-sonic Percutaneous Nephrolithotomy in Large Kidney Stones NCT02751281 | Isfahan University of Medical Sciences | Phase 2 |
| Terminated | Effectiveness of Silodosin in Medical Expulsive Therapy for Ureteral Pelvic Stone From 4 to 10 mm. NCT02090439 | Centre Hospitalier Departemental Vendee | Phase 3 |
| Unknown | Swiss Kidney Stone Cohort (SKSC) NCT01990027 | The Swiss National Centre of Competence in Research Kidney Control of Homeostasis | — |
| Withdrawn | Potassium Citrate Supplementation vs. Dietary Counseling NCT01980004 | University of North Carolina, Chapel Hill | Phase 2 |
| Completed | Fluid Intake Application to Reduce Kidney Stone Risks NCT01928108 | University of North Carolina, Chapel Hill | — |
| Terminated | The Effect of Ureteric Stent Tethers on Patient Symptoms and Urinary Infection NCT01812772 | Unity Health Toronto | N/A |
| Unknown | SNP-based Prediction of Recurrence Risk in Kidney Stone Patients NCT04937192 | The First Affiliated Hospital of Guangzhou Medical University | — |
| Unknown | Lime Powder Regimen in Healthy Volunteers NCT01273025 | Chulalongkorn University | Phase 1 |
| Unknown | A Clinical Study of the Living Renal Transplantation With Restored Kidneys Between Family Members NCT00994188 | Tokushukai Medical Group | N/A |
| Completed | Effect of Tamsulosin on Stone Expulsion and Pain Resolution in ED Patients With Ureterolithiasis NCT00762424 | WellSpan Health | N/A |
| Completed | Pharmacological Modulation of the Intrarenal Pressure During Endourological Procedures in the Upper Urinary Tr NCT00428428 | Fredericia Hosptial | Phase 2 / Phase 3 |
| Completed | An Analgesia Protocol for Acute Renal Colic in the Emergency Department NCT00504283 | Dartmouth-Hitchcock Medical Center | N/A |
| Unknown | Retrograde Intrarenal Stone Surgery - A Method of Treating the ESWL Resistant Kidney Stone NCT00323843 | Fredericia Hosptial | Phase 2 |
| Completed | Effect of Cola on Urinary Stone Risk Factors NCT00289120 | Emory University | N/A |
| Completed | Adjunct Inversion for Lower Pole Stone NCT01852669 | Monash University | N/A |