NCT04727606

Research Project: Pilot Study on Oral Urea Use in Patients at High Risk of Kidney Stone Recurrence

• Status: Withdrawn
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Centre hospitalier de l'Université de Montréal (CHUM) · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

In clinical practice, many patients are not able to modify their habits to achieve a high level of diuresis and fluid intake and therefore are at an elevated risk for stone recurrence. The investigators think that Ure-Na (osmotic agent) taking could help to increase urine volume and decrease urine concentration, which would be of benefit in the prevention of kidney stones.

Conditions

• Kidney Stone

Interventions

Type	Name	Description
DRUG	Ure-Na	* Participants in the study will receive Oral Urea (Ure-Na) treatment at a dose of 30 grams per day (2 x 15 gram pouches per day) * Treatment will continue for approximately 1 month.

Timeline

• Start date: 2023-01-15
• Primary completion: 2024-01-15
• Completion: 2024-06-15
• First posted: 2021-01-27
• Last updated: 2022-11-28

Locations

1 site across 1 country: Canada

Regulatory

• FDA-regulated drug study