NCT03060837

Investigate the Renal Movement by Single Lung Ventilation in Patients Administered RIRS for Kidney Stones.

To Investigate the Effect of Reducing Renal Movement by Single Lung Ventilation in Patients Administered Retrograde Infrarenal Surgery (RIRS) for Kidney Stones on Operative and Postoperative Parameters

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (estimated)
• Sponsor: Kahramanmaras Sutcu Imam University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

In patients undergoing RIRS for kidney stone, we aim to show the effect of single lung ventilation with a double lumen tube on operative (operation scope duration, perforation, hemorrhage, etc. complications) and postoperative parameters (stone-free rates, complications like postoperative hemorrhage and fever, hospital stay, etc.) and to show changes in renal stone position during simultaneous normal ventilation and single lung ventilation.

Detailed description

In recent years open surgical treatment has changed to minimal invasive treatments for kidney stone treatment. Additionally, the treatment choices vary depending on the localization of the stone and its dimensions. In the European Urology Association (EUA) guidelines, it states the RIRS method can be used to treat stones up to 2 cm in the kidney. Due to RIRS the operation and scopy durations and hospital stay have clearly reduced compared to the standard treatment of percutaneous nephrolithotomy. However, the high hydrostatic pressure applied to the renal pelvis during RIRS may cause unwanted results in the postoperative period such as hydronephrosis and loss of renal parenchyma. During the operation, the stone may move during deep inspirium and expirium sequences linked to deep ventilation which may lengthen the operation and scope durations and brings risks such as perforation during laser lithotripsy application. In this study we aimed to apply single lung ventilation during the operation (one of the indications for single lung ventilation is to increase surgical view and ease manipulation) to minimize renal movement on that side and reduce peroperative and postoperative complications.

Conditions

• Perioperative/Postoperative Complications
• Kidney Stone

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Preoperative Parameters	Preoperative Hmg and serum creatinine levels
OTHER	Peroperative Parameters	Scope duration, perforation, hemorrhage, etc. complications
OTHER	Postoperative Parameters	Stone-free rates, complications like postoperative hemorrhage and fever, hospital stay, etc
OTHER	Movement of kidney	Changes in renal stone position during simultaneous normal ventilation and single lung ventilation.
PROCEDURE	single lung ventilation	Patients in this group will intubated with an endotracheal tube and then a bronchial blocker will be placed with the help of a fiberoptic bronchoscope or will be intubated with a double lumen endobronchial tube. One lung ventilation will be applied
PROCEDURE	standard ventilation	Patients in this group will be intubated with standart single lumen endotracheal tubes and standart two lung ventilation will be applied.

Timeline

• Start date: 2017-03-01
• Primary completion: 2020-02-20
• Completion: 2020-03-01
• First posted: 2017-02-23
• Last updated: 2020-02-20

Locations

1 site across 1 country: Turkey (Türkiye)