| Recruiting | Efficacy and Safety of Sanggua Tablets in the Treatment of Patients With Impaired Glucose Tolerance and Mild T NCT06964620 | Tongji Hospital | EARLY_Phase 1 |
| Recruiting | Night Owl Metabolism NCT06507722 | Johns Hopkins University | N/A |
| Terminated | Metabolic Adaptations to High-fat Diet NCT06537401 | George Washington University | N/A |
| Not Yet Recruiting | Preliminary Safety and Efficacy Study of Extracellular Vesicle Infusion in the Intervention of Age-related Phe NCT06495437 | BEAUTECH | N/A |
| Completed | Effect of a Food Supplement Based on Nigella Sativa Seeds Oil and Vitamin E on Glyco-lipid Parameters in Dysgl NCT06901076 | Fondazione IRCCS Policlinico San Matteo di Pavia | N/A |
| Unknown | Evaluation of the Safety and Efficacy of SGLT2 Inhibitors in Pre-diabetic Patients NCT05914857 | Yangjin | Phase 2 |
| Active Not Recruiting | Semaglutide Effects in Obese Youth With Prediabetes/New Onset Type 2 Diabetes and Metabolic Dysfunction-Associ NCT05067621 | Yale University | Phase 2 |
| Recruiting | The Effects of an Obesogenic Lifestyle in Recreationally Active, Young Adults NCT05912348 | University of New Hampshire | N/A |
| Recruiting | CGM and Lifestyle Changes in Patients With Impaired Glucose Tolerance NCT05387551 | Nemours Children's Clinic | N/A |
| Unknown | Influence of Preprandial Metformin Administration on Carbohydrate Absorption NCT04018105 | University Hospital, Lille | N/A |
| Completed | High FODMAP Diet With Metformin in preDM NCT05628584 | Elaine Chow | N/A |
| Unknown | Acupuncture for Impaired Glucose Tolerance in Overweight/Obese Population NCT05347030 | Yan Yan | N/A |
| Completed | Using a Complex Carbohydrate Mixture to Steer Fermentation and Improve Metabolism in Adults With Overweight an NCT05354245 | Maastricht University Medical Center | N/A |
| Recruiting | Glucose Intolerance and Diabetes Related to Treatment With Steroids and PEG- Asparaginase in Children and Adol NCT05873322 | Aarhus University Hospital | — |
| Completed | Effects of an Intermittent Fasting and Dietary Supplement Regimen on Glycemic Variability NCT05493553 | Unicity International, Inc. | N/A |
| Completed | The Effect of Long-term Momordica Charantia Supplementation on Blood Glucose Levels NCT05215210 | Wageningen University and Research | N/A |
| Terminated | Glucose Homeostasis and Apple Polyphenols NCT05951270 | Maastricht University | N/A |
| Completed | Effectiveness and Cost-Effectiveness of Fully-Automated Digital vs. Human Coach-Based Diabetes Prevention Prog NCT05056376 | Johns Hopkins University | N/A |
| Unknown | Effect of F. Prausnitzii on Glycemic Control NCT04938843 | MetaboGen AB | N/A |
| Completed | HSK7653 in Chinese Patients with Impaired Glucose Tolerance NCT04727580 | Haisco Pharmaceutical Group Co., Ltd. | Phase 2 |
| Unknown | Decrease Type II Diabetes in Gestational Diabetes Population NCT05202002 | Carmel Medical Center | N/A |
| Unknown | Effects of Glucose Lowering Agents in South Asian Women With Impaired Glucose Tolerance or Impaired Fasting Gl NCT04662866 | Oslo University Hospital | Phase 2 |
| Completed | Efficacy and Safety of 12-weeks Supplementation of Eubacterium Hallii on Insulin Sensitivity and Glycaemic Con NCT04529473 | Atlantia Food Clinical Trials | N/A |
| Active Not Recruiting | The Renin-Angiotensin-Aldosterone System in Adiposity, Blood Pressure and Glucose in African Americans NCT03938389 | Ohio State University | Phase 4 |
| Completed | Type 2 Diabetes Mellitus Prevention Ukraine NCT04283201 | Komisarenko Institute of Endocrinology and Metobolism | Phase 2 |
| Active Not Recruiting | Effect of Probiotics Versus Metformin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Predia NCT04341571 | University of Guadalajara | Phase 2 |
| Completed | Clinical Trial of Efficacy and Safety of Subetta in the Treatment of Impaired Glucose Tolerance NCT03725033 | Materia Medica Holding | Phase 3 |
| Completed | Health Effects of Salmon Fishmeal in Humans NCT03764423 | University of Oslo | N/A |
| Completed | Mechanisms of Exercise Resistance in Metabolic Disease NCT03945435 | Joslin Diabetes Center | — |
| Completed | A Crossover Trial of Chitosan Oligosaccharide on Post Prandial Glucose Control in Subjects With Normal, IFG an NCT03650023 | Yonsei University | N/A |
| Completed | Almonds and Health Effects on Metabolism, Vascular Function and Cognition NCT03419702 | Maastricht University Medical Center | N/A |
| Unknown | Mechanisms Underlying the Regulation of Impaired Glucose Tolerance by Auricular Concha Electro-acupuncture NCT03343262 | China Academy of Chinese Medical Sciences | N/A |
| Unknown | Research of Intensive Metabolic Intervention Before Pregnancy in PCOS NCT03383068 | RenJi Hospital | Phase 4 |
| Completed | The Interaction Between Metformin and Acute Exercise NCT03329651 | Kristian Karstoft | N/A |
| Completed | The Interaction Between Metformin and Physical Training NCT03316690 | Kristian Karstoft | N/A |
| Withdrawn | Personalized Smartphone-assisted Coaching System to Improve Glucose Homeostasis in Adults With Prediabetes - M NCT03315663 | Johns Hopkins University | N/A |
| Completed | Postprandial Fatty Acid Metabolism in the Natural History of Type 2 Diabetes (T2D) NCT02808182 | Université de Sherbrooke | N/A |
| Completed | Sucralose, Stevia, Gut Microbiome and Glucose Metabolism NCT02800707 | University of Minnesota | N/A |
| Completed | Personalized Smartphone-assisted Coaching System to Improve Glucose Homeostasis in Adults With Prediabetes NCT02896010 | Johns Hopkins University | N/A |
| Completed | Effect of Dapagliflozin on Insulin Secretion and Insulin Sensitivity in Patients With Prediabetes NCT02700334 | University of Guadalajara | Phase 4 |
| Completed | Effect of Linagliptin + Metformin on Patients Who do Not Achieve Normoglucemia With Metformine NCT04088461 | Universidad de Guanajuato | Phase 4 |
| Unknown | The Long-term Effect of Tianqi Capsule Interventions to Prevent Diabetes in the REDUCES Study: a 8-year Follow NCT02848053 | Guang'anmen Hospital of China Academy of Chinese Medical Sciences | — |
| Completed | Effects of Artificial Sweeteners on Gut Microbiota and Glucose Metabolism NCT02569762 | University of Manitoba | N/A |
| Completed | Glycemic and Insulinemic Impact of Selected Canadian Beans NCT02907190 | Guelph Food Research Centre | N/A |
| Completed | Effect of Gymnema Sylvestre on Patients With Impaired Glucose Tolerance. NCT02708966 | University of Guadalajara | Phase 2 |
| Unknown | Effect of Berberine Versus Metformin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Prediab NCT03029390 | University of Guadalajara | Phase 4 |
| Completed | Effect of Chlorogenic Acid on Patients With Impaired Glucose Tolerance NCT02621060 | University of Guadalajara | Phase 2 |
| Completed | Effects of Lignan-rich Diet on Cardiometabolic Risk Factors NCT02987595 | Swedish University of Agricultural Sciences | N/A |
| Withdrawn | Psoriatic Arthritis Treated With Liraglutide Therapy: a QUality of Life and Efficacy Study NCT02472717 | University Health Network, Toronto | Phase 2 |
| Completed | Effects of D-allulose (Psicose) With Sucrose Beverage on Glucose Tolerance and Insulin Level NCT02455934 | Chiang Mai University | N/A |
| Completed | Efficiency and Cost-effectiveness of a Culturally Adopted Lifestyle Intervention Program - the MEDIM Study. NCT01420198 | Region Skane | N/A |
| Completed | Dose-dependent Effect of Grape Seed Extract on Glucose Control in People With Impaired Glucose Tolerance NCT02254317 | Clinical Nutrition Research Center, Illinois Institute of Technology | N/A |
| Completed | Effects of Dietary Ingredients on Vascular Function NCT02158481 | Unilever R&D | N/A |
| Completed | Liquid Protein Preloads With Different Carbohydrate Types Effects on the Glycaemic and Insulinaemic Response NCT02151188 | Singapore Institute of Food and Biotechnology Innovation | N/A |
| Terminated | Step Up For Health Study: A Pedometer and Website Intervention in Those With Prediabetes NCT05412264 | University of Alberta | N/A |
| Completed | Meal Patterning on Weight Loss With Changes to Body Comp, Muscle and Metabolic Health NCT02066948 | Purdue University | N/A |
| Completed | Improving Autonomic Function and Balance in Diabetic Neuropathy NCT01864460 | VA Office of Research and Development | N/A |
| Completed | Studying the Effect of Capsinoids on Brown Fat Using Infrared Thermal Imaging. NCT01961674 | Singapore Institute of Food and Biotechnology Innovation | N/A |
| Completed | Breaks in Sedentary Time and Glucose Regulation in Women NCT02135172 | University of Leicester | N/A |
| Unknown | ARA290 in T2D (Effects of ARA 290, an Erythropoietin Analogue) in Prediabetes and Type 2 Diabetes) NCT01933529 | Claes-Göran Östenson | Phase 2 |
| Completed | Measurement of the Free Fraction of 25-hydroxyvitamin D in Serum NCT01771380 | University of Tromso | — |
| Unknown | Effect of Ginseng on Glycemic Control NCT01841229 | Unity Health Toronto | — |
| Completed | Effect of Sitagliptin on Short-Term Metabolic Dysregulation of Oral Glucocorticoid Therapy NCT01488279 | University of Vermont | N/A |
| Completed | ACute and Chronic Effects of Saxagliptin NCT01521312 | Assistance Publique - Hôpitaux de Paris | Phase 2 |
| Completed | The Effect of Real Time Continuous Glucose Monitoring in Subjects With Pre-diabetes NCT01741467 | Walter Reed National Military Medical Center | N/A |
| Completed | Resveratrol-Leucine Metabolite Synergy in Pre-diabetes NCT01593605 | Vanderbilt University | N/A |
| Terminated | Effect of Saxagliptin Treatment on Myocardial Fat Content, and Monocyte Inflammation NCT01548651 | Baylor College of Medicine | Phase 4 |
| Completed | Effects of Pinitol on Hidrocarbonated Metabolism Parameters in Diabetic, Impaired and Normal Fasting Glucose S NCT01754792 | University of Valencia | N/A |
| Completed | Effect of Meal Frequency on Glycemic Control of People at High Risk or Diagnosed With Diabetes NCT02248272 | Meropi Kontogianni | N/A |
| Completed | Egg Protein Hydrolysate and Vascular Function NCT01559896 | Maastricht University Medical Center | N/A |
| Completed | Mood and Insulin Resistance in Adolescents At-Risk for Diabetes NCT01425905 | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Phase 2 |
| Completed | Combined Liraglutide and Metformin Therapy in Women With Previous Gestational Diabetes Mellitus (GDM) NCT01234649 | Woman's | Phase 3 |
| Terminated | Renin-Angiotensin and Fibrinolysis in Humans: Effect of Long-Term PDE5 Inhibition on Glucose Homeostasis NCT01409993 | Vanderbilt University | Phase 4 |
| Completed | Effect of Dietary Glycemic Index on Beta-cell Function NCT01386645 | Seattle Institute for Biomedical and Clinical Research | N/A |
| Unknown | Safety, Tolerability, PK, and PD of LIM-0705 in Subjects With Impaired Glucose Tolerance or Abnormal HOMA-IR NCT01364155 | Limerick BioPharma | Phase 2 |
| Completed | D Vitamin Intervention in VA NCT01375660 | US Department of Veterans Affairs | N/A |
| Completed | Evaluation of Low Source of Signal in SCOUT DS NCT01339637 | VeraLight, Inc. | — |
| Completed | Pilot Study of Resveratrol in Older Adults With Impaired Glucose Tolerance NCT01375959 | Albert Einstein College of Medicine | N/A |
| Unknown | Effect of High Fiber and Sugar Free Biscuits in Prediabetics Population NCT01330550 | China Medical University Hospital | N/A |
| Terminated | GLU-xx Formulations in Individuals With Impaired Glucose Tolerance NCT01468376 | Afexa Life Sciences Inc | Phase 1 |
| Completed | Skin Autofluorescence (AF) Decision Tree in Detecting Impaired Glucose Tolerance (IGT) or Diabetes Mellitus (D NCT01406665 | University Medical Center Groningen | — |
| Completed | Teplizumab for Prevention of Type 1 Diabetes In Relatives "At-Risk" NCT01030861 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Phase 2 |
| Completed | Effects of Physical Activity on the Brain in Impaired Glucose Tolerance (IGT) NCT01219231 | Charite University, Berlin, Germany | Phase 4 |
| Unknown | Cystic Fibrosis (CF) Exacerbation and Insulin Treatment NCT01149005 | Hadassah Medical Organization | N/A |
| Withdrawn | Investigation of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LIM-0705 in Male Subjects NCT01093677 | Limerick BioPharma | Phase 1 |
| Completed | To Compare the Effect of a Subcutaneous Canakinumab Administration to Placebo in Patients With Impaired Glucos NCT01068860 | Novartis | Phase 2 |
| Completed | Glucose Control in Pre-Diabetic Renal Transplant Patients NCT01346254 | Marcus Saemann | Phase 2 |
| Unknown | Effect of Sitagliptin in Impaired Glucose Tolerance NCT00961363 | National Taiwan University Hospital | Phase 2 |
| Completed | Voglibose Tablets 0.2 / OD Tablets 0.2 Special Drug Use Surveillance "Long-term Use in Patients With Impaired NCT01993927 | Takeda | — |
| Completed | Prevention of Type 2 Diabetes in Children With a Family-based Healthy Lifestyle Program NCT01030978 | Yale University | N/A |
| Completed | The Effect of Nordic Recommended Diet on the Features of Metabolic Syndrome - Multicentre Study NCT00992641 | Marjukka Kolehmainen | N/A |
| Completed | Pilot Study With GFT505 (80mg) in Patients Presenting With Impaired Glucose Tolerance and Abdominal Obesity. NCT01275469 | Genfit | Phase 2 |
| Completed | Electrodiagnostic Parameters in Patients With Impaired Glucose Tolerance and Diabetes Mellitus NCT01094418 | The Catholic University of Korea | — |
| Unknown | Impact of Acarbose on Abnormal Glucose Regulation in Patients With Coronary Artery Disease (AAA Trial) NCT00858676 | Aichi Gakuin University | Phase 4 |
| Completed | Acarbose Cardiovascular Evaluation Trial NCT00829660 | University of Oxford | Phase 4 |
| Completed | Evaluation of Soluble Epoxide Hydrolase (s-EH) Inhibitor in Patients With Mild to Moderate Hypertension and Im NCT00847899 | Arete Therapeutics | Phase 2 |
| Completed | The Role of Pulsatile Insulin Secretion (A Study Investigating the Effects of Partial Pacreatectomy on Glucose NCT00841867 | University of California, Los Angeles | — |
| Completed | Enhancing Fitness in Older Pre-diabetic Veterans NCT00594399 | US Department of Veterans Affairs | Phase 2 / Phase 3 |
| Withdrawn | The Effects of Exenatide on Post-Meal Sugar Peaks and Vascular Health in Obese/Pre-Diabetic Young Adults NCT00845559 | Yale University | Phase 4 |
| Unknown | Evaluation of Intervention on Impaired Glucose Tolerance(IGT) in Patients With Coronary Heart Disease. NCT00724542 | Ministry of Science and Technology of the People´s Republic of China | N/A |
| Completed | Low Density Lipoprotein (LDL) Cholesterol Metabolism in Impaired Glucose Tolerance NCT01020578 | University of Sao Paulo General Hospital | — |
| Completed | Co-treatment With Pegvisomant and a Somatostatin Analogue (SA) in SA-responsive Acromegalic Patients NCT00652379 | University of Aarhus | N/A |
| Completed | Beta-cell Function in Glucose Abnormalities and Acute Myocardial Infarction NCT00627744 | Karolinska Institutet | Phase 4 |
| Completed | Glucose Tolerance in Acromegaly: The Influence of GH-excess on Glucose Metabolism and Insulin Resistance NCT00663000 | University Hospital Tuebingen | — |
| Completed | Vitamin D for the Prevention of Diabetes Type 2 NCT00685594 | University of Tromso | Phase 2 / Phase 3 |
| Completed | Treatment of Impaired Glucose Tolerance in Pregnancy NCT00625781 | Region Örebro County | N/A |
| Completed | Cassia Cinnamon for Glucose Uptake in Young Women NCT00951639 | Baylor University | N/A |
| Completed | Dietary Modulation of Hepatic Lipase (LIPC) -514 C/T Variant Associations With Lipids and Glucose NCT02938091 | Tufts University | N/A |
| Completed | The Vascular Effects of Exenatide Versus Metformin in Patients With Pre-Diabetes NCT00546728 | St. Paul Heart Clinic | Phase 4 |
| Completed | Effect of Increased Intake of Low Fat Dairy Products on Weight Loss and Insulin Resistance NCT00564551 | University of Calgary | N/A |
| Completed | Dietary Modulation of Gene Expression and Metabolic Pathways in Glucose Metabolism NCT00573781 | Marjukka Kolehmainen | Phase 2 |
| Terminated | Chronic Inflammatory Activation in Fat Tissue: An Atherogenic Factor in Severe Coronary Artery Disease NCT00510705 | University of Leipzig | N/A |
| Completed | Chronic Inflammatory Activation in Fat Tissue: an Atherogenic Factor in Stable Coronary Artery Disease NCT00510588 | University of Leipzig | N/A |
| Completed | Effect of Pioglitazone and Exenatide on Body Weight and Beta Cell Function NCT00845182 | The University of Texas Health Science Center at San Antonio | Phase 4 |
| Completed | Effects of Colesevelam HCl On Bile Acid Kinetics NCT00476710 | KineMed | — |
| Completed | Anti-Inflammatory Effects of Pioglitazone NCT00722631 | Kurume University | N/A |
| Completed | The Effect of Exenatide on Weight and Hunger in Obese, Healthy Women NCT00456885 | Beth Israel Deaconess Medical Center | Phase 4 |
| Unknown | The Effects of Exercise on Adipokine in Impaired Fasting Glucose or Impaired Glucose Tolerance Patients NCT00472342 | Yonsei University | N/A |
| Completed | Progression to Impaired Glucose Tolerance and Type 2 Diabetes in the Korean People-based KNDP Study NCT01034826 | Korea University Guro Hospital | — |
| Unknown | Additional Glucose Lowering and Anti-Inflammatory Effects by Acarbose and Alcohol in Subjects With Impaired Gl NCT00417950 | Taichung Veterans General Hospital | N/A |
| Terminated | Study of Post-meal Blood Sugar Peaks in Association With Vascular Disease in Childhood Obesity NCT00846521 | Yale University | Phase 4 |
| Completed | Effects of Exenatide on Postprandial Hyperlipidemia and Inflammation NCT00974272 | Carl T. Hayden VA Medical Center | Phase 4 |
| Unknown | Exercise Effects on Cardiovascular Risk Factors, Quality of Life, Muscle Function in Type 2 Diabetes and Healt NCT00852982 | Karolinska Institutet | N/A |
| Completed | The Health Effect of Diet Rich in Nordic Berries NCT01414647 | Marjukka Kolehmainen | N/A |
| Completed | Prevention of Type 2 Diabetes Mellitus by L-Arginine in Patients With Metabolic Syndrome NCT00917449 | IRCCS San Raffaele | Phase 3 |
| Completed | Effects of Rosiglitazone on the Metabolic Phenotype of Impaired Glucose Tolerance in Youth NCT00413335 | Yale University | N/A |
| Unknown | Type 2 Diabetes and Acute Myocardial Infarction NCT00926133 | Ullevaal University Hospital | — |
| Completed | Treating the Endothelium to Restore Insulin Sensitivity NCT00402194 | Indiana University School of Medicine | N/A |
| Completed | Cardiovascular Disease (CVD) Risk and Prevention in Early Glucose Intolerance NCT00122447 | Emory University | N/A |
| Completed | Chromium Effects on Insulin and Vascular Function in People at Risk for Diabetes NCT00067626 | Griffin Hospital | Phase 2 |
| Terminated | Assessment of an Alpha-glucosidase Inhibitor to Block Cardiac Events in Patients With MI and IGT NCT00212017 | National Cerebral and Cardiovascular Center, Japan | N/A |
| Completed | Telmisartan and Losartan in Hypertensive IGT NCT00407862 | Medical University of Graz | Phase 4 |
| Completed | Cognitive Effects of Aerobic Exercise for IGT Adults NCT00220441 | Seattle Institute for Biomedical and Clinical Research | Phase 2 |
| Completed | A Lifestyle and Combination Medication Therapy Diabetes Prevention Study NCT00116922 | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | Phase 3 |
| Completed | 11ß-HSD1 and Metabolic Syndrome NCT00370305 | Charite University, Berlin, Germany | Phase 2 |
| Unknown | Rosiglitazone Therapy In The Prevention Of Coronary Artery Disease In Patients With Impaired Glucose Tolerance NCT00733174 | Denver Research Institute | Phase 4 |
| Completed | Effective Endurance Training in Metabolic Syndrome NCT00218998 | Norwegian University of Science and Technology | N/A |
| Completed | Actos Now for Prevention of Diabetes (ACT NOW) NCT00220961 | The University of Texas Health Science Center at San Antonio | Phase 3 |
| Completed | Physical Exercise Versus Rosiglitazone in CAD and Prediabetes NCT00675740 | University of Leipzig | Phase 4 |
| Completed | Effects of Treatment of Sleep Apnea on Metabolic Syndrome NCT01385995 | Brigham and Women's Hospital | Phase 2 |
| Completed | Study to Determine the Effects of Human Growth Hormone and Pioglitazone in Overweight, Prediabetic Adults NCT00352287 | Stanford University | Phase 4 |
| Completed | To Investigate the Effect of Rosiglitazone and Ramipril on Pre-clinical Vasculopathy in Diabetes and IGT Patie NCT00489229 | Universiti Sains Malaysia | Phase 3 |
| Completed | Clinical Trial To Evaluate The Effect Of Valsartan On Insulin Sensitivity In Subjects With Impaired Glucose To NCT00241072 | Novartis | Phase 4 |
| Completed | Study to Investigate the Pathophysiology of Type 2 Diabetes in Youth NCT00536250 | Yale University | — |
| Completed | The DREAM (Diabetes Reduction Assessment With Ramipril and Rosiglitazone Medication) Trial NCT00095654 | Gerstein, Hertzel, MD | Phase 3 |
| Completed | The Study of Atherosclerosis With Ramipril and Rosiglitazone NCT00140647 | Gerstein, Hertzel, MD | Phase 3 |
| Completed | Impact of 3-year Lifestyle Intervention on Postprandial Glucose Metabolism: the SLIM Study NCT00381186 | Maastricht University Medical Center | N/A |