Clinical Trials Directory

Trials / Completed

CompletedNCT00546728

The Vascular Effects of Exenatide Versus Metformin in Patients With Pre-Diabetes

The Chronic and Acute Postprandial Vascular Effects of Exenatide vs. Metformin in Abdominally Obese Patients With Impaired Glucose Tolerance

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
50 (actual)
Sponsor
St. Paul Heart Clinic · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to compare the effects of exenatide versus metformin on vascular health with chronic (3-month) therapy and during a 2-hour period following a meal in patients with pre-diabetes. It is predicted that exenatide will improve vascular health to a greater degree compared to metformin.

Conditions

Interventions

TypeNameDescription
DRUGExenatideexenatide 10 mcg twice daily
DRUGMetforminmetformin 500 twice daily

Timeline

Start date
2007-10-01
Primary completion
2011-07-01
Completion
2011-07-01
First posted
2007-10-19
Last updated
2013-11-08
Results posted
2013-11-08

Locations

2 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00546728. Inclusion in this directory is not an endorsement.

The Vascular Effects of Exenatide Versus Metformin in Patients With Pre-Diabetes (NCT00546728) · Clinical Trials Directory