| Recruiting | The Benefits of Natural Medicine, Vitamin IV Therapy and Supplements: Maintaining Good Health Through Nature NCT05067998 | Faith A. Richardson | — |
| Enrolling By Invitation | Engaging Home-monitored Assessment to Navigate Clinical Decision-making NCT07399912 | SingHealth Polyclinics | N/A |
| Recruiting | Renal Artery Denervation Assessment Without Antihypertensive Medication Regimen (RADAR) NCT07083765 | Ablative Solutions, Inc. | Phase 3 |
| Not Yet Recruiting | Treatment and Handling Severe Obesity-Related Comorbidities in Adolescents Through Exercise NCT06520800 | University of Lisbon | N/A |
| Active Not Recruiting | Food is Medicine vs Lifestyle Medicine For Cardiovascular Kidney Metabolic (CKM) Syndrome NCT06461273 | Rutgers, The State University of New Jersey | N/A |
| Completed | Study of SGB-3908 in Healthy Subjects and Mildly Hypertensive Subjects NCT06501586 | Suzhou Sanegene Bio Inc. | Phase 1 |
| Recruiting | Efficacy and Safety of SPC1001 in Patients With Essential Hypertension NCT06826872 | Shin Poong Pharmaceutical Co. Ltd. | Phase 2 |
| Recruiting | Phase III Study to Evaluate the Efficacy and Safety of AD-209 NCT06348576 | Addpharma Inc. | Phase 3 |
| Recruiting | A Study to Evaluate the Efficacy and Safety of AD-224 NCT06291207 | Addpharma Inc. | Phase 3 |
| Recruiting | Efficacy of Songling Xuemaikang Capsules on Grade 1 Hypertension: a Randomized Controlled Trial NCT06093932 | Xiyuan Hospital of China Academy of Chinese Medical Sciences | Phase 4 |
| Not Yet Recruiting | Endothelial Function in Prehypertension NCT06316271 | Josip Juraj Strossmayer University of Osijek | — |
| Active Not Recruiting | Safety, Tolerability, PK and PD of ADX-850 in Participants With Hypertension NCT06205628 | ADARx Pharmaceuticals, Inc. | Phase 1 |
| Completed | A Study to Evaluate the Efficacy and Safety of AD-223 NCT06052748 | Addpharma Inc. | Phase 3 |
| Unknown | Effect of Isometric and Aerobic Physical Exercise on Blood Pressure Levels in Hypertensive Elderly People NCT06282302 | Instituto de Cardiologia do Rio Grande do Sul | N/A |
| Recruiting | BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT NCT06059638 | Orchestra BioMed, Inc | N/A |
| Unknown | Effects of Electrical Nervous Stimulation Transcutaneous in Hypertensive Patients NCT06025643 | Federal University of Health Science of Porto Alegre | N/A |
| Completed | Licorice and Home Blood Pressure, Additional Study NCT06019598 | Linkoeping University | N/A |
| Recruiting | Mobile Health Program for Rural Hypertension NCT05546931 | University of Pittsburgh | N/A |
| Completed | Functional Inspiratory Muscle Training in Patients Diagnosed With Hypertension NCT06343246 | Mustafa Kemal University | N/A |
| Completed | A Study to Evaluate the Efficacy and Safety of AD-209 NCT05631990 | Addpharma Inc. | Phase 2 |
| Completed | Licorice and Home Blood Pressure NCT05661721 | Linkoeping University | N/A |
| Completed | Health Expenses and Outcomes of the DASH Diet in Egyptian Patients With Hypertension NCT06499194 | Beni-Suef University | N/A |
| Unknown | Efficacy and Safety Study of the Fixed-dose Combination of Olmesartan + Indapamide When Compared to the Isolat NCT05110898 | Brainfarma Industria Química e Farmacêutica S/A | Phase 3 |
| Active Not Recruiting | Long-term Use of CCB and Breast Cancer Risk NCT05972785 | Curtin University | — |
| Recruiting | An OS to Evaluate Effectiveness and Safety of Fixed-dose Combinations of FMS/AML or FMS/AML/HCTZ NCT05413057 | Boryung Pharmaceutical Co., Ltd | — |
| Completed | Left Atrial Enlargement: A Crucial Indicator for Identifying Atrial Fibrillation in Patients With Hypertension NCT06359873 | The Second Affiliated Hospital of Chongqing Medical University | — |
| Completed | The Significance of Sodium Balance and the Value of Salt-blood Test in Identifying Salt Sensitive Patients NCT05165823 | Regional Hospital Holstebro | N/A |
| Completed | Recreational Futsal for Controlled Hypertension NCT05185297 | University Institute of Maia | N/A |
| Completed | An Observation Study to Evaluate the Renoprotective Effect of Fimasartan in Patients With DKD and Proteinuria NCT05086549 | Boryung Pharmaceutical Co., Ltd | — |
| Unknown | Cardiac Neuromodulation Therapy (CNT) "Washout" Sub-Study NCT05086523 | BackBeat Medical Inc | Phase 1 / Phase 2 |
| Completed | The Antihypertensive Effect of Remote Ischemic Conditioning (RIC-HTN). NCT04915313 | Capital Medical University | N/A |
| Recruiting | Improving Hypertension Control in CHina and ARGEntina With a Mobile APP-based Telecare System NCT03206814 | Istituto Auxologico Italiano | N/A |
| Completed | Non-Inferiority Study of Aliskiren vs Losartan in the Treatment of Hypertension With Hyperuricemia NCT06718062 | Hansung University | Phase 4 |
| Completed | Management of Hypertension Utilizing Trained Community Health Worker in Rural Municipalities of Nepal NCT04521582 | Johns Hopkins Bloomberg School of Public Health | N/A |
| Unknown | Hypertension Treatment Adherence Improving Trial NCT04565548 | The Hong Kong Polytechnic University | N/A |
| Unknown | The Föllinge Hypertension and Lifestyle Study NCT04488289 | Umeå University | N/A |
| Unknown | Wearable Blood Pressure Devices to Identify Masked Uncontrolled Hypertension. NCT04863508 | National Taiwan University Hospital Hsin-Chu Branch | — |
| Completed | Phase 3 Study to Evaluate the Efficacy and Safety of Co-administrated AD-2021 and AD-2022 NCT06448962 | Addpharma Inc. | Phase 3 |
| Unknown | The Association Between Serum β-hydroxybutyrate and Levels of Systemic Hypertension NCT04332562 | Sulaiman AlRajhi Colleges | N/A |
| Completed | Determining the Optimal Dose of AD-209 in Patients With Essential Hypertension NCT04218552 | Addpharma Inc. | Phase 2 |
| Unknown | A Real World Research: Comparison of Precision and Experience Therapy for Hypertension, Diabetes or Hyperlipid NCT04660630 | Beijing Chao Yang Hospital | N/A |
| Completed | A Cardiosleep Research Program on Obstructive Sleep Apnea, Blood Pressure Control and Maladaptive Myocardial R NCT04119999 | National University of Singapore | N/A |
| Recruiting | Optical Coherence Tomography Angiography in Subjects With Retinal Vascular Disease NCT04505618 | Johns Hopkins University | N/A |
| Unknown | Screening, Early Referral and Lifestyle Tailored E_prescription for Cardiovascular Prevention NCT04082091 | Aga Khan University | — |
| Recruiting | Genetic of Response to Acute Saline Load Test in Hypertension (Naload) NCT04625569 | Ospedale San Raffaele | — |
| Completed | Plant-based Nutrition for Patients With Cardiovascular Risk Factors NCT03901183 | Charite University, Berlin, Germany | N/A |
| Recruiting | Blood Pressure Reduction in Patients With Asymptomatic Aortic VALVE Stenosis NCT04613193 | Henrik Wiggers | N/A |
| Completed | Impact of Aerobic Exercise Training on Sympathetic Vasoconstriction and Vascular Function in Essential Hyperte NCT03778489 | University of Copenhagen | N/A |
| Completed | Safety and Efficacy of SPH3127 on Treating Mild-moderate Essential Hypertension Patients NCT03756103 | Shanghai Pharmaceuticals Holding Co., Ltd | Phase 2 |
| Completed | HIV, Immune Activation and Salt Sensitive Hypertension NCT04459741 | Mulungushi University | N/A |
| Completed | Prescribing Patterns of Antihypertensive Drugs in Uncomplicated Hypertension NCT06517134 | University Hospital, Caen | — |
| Completed | Natriuretic Effect of Amiloride in Relation to the Alpha Adducin Gene (ADD-AMI) RS4961 Variant NCT06416735 | Ospedale San Raffaele | Phase 3 |
| Completed | The TARGET BP OFF-MED Trial NCT03503773 | Ablative Solutions, Inc. | Phase 2 |
| Completed | Brain BOLD fMRI in Hypertensive and Normotensive Participants NCT03473275 | Centre Hospitalier Universitaire Vaudois | — |
| Completed | Effects of TENS and IES on the Autonomous Balance of Normotens Volunteers and Hypertensive Patients NCT03258489 | Universidade Federal de Santa Maria | N/A |
| Completed | The Accumbo Home Blood Pressure Trial NCT03908710 | Accumbo AB | N/A |
| Unknown | Effect of High-Intensity Interval Training Compared to Hydrochlorothiazide on Ambulatory Blood Pressure NCT04103411 | Anil Nigam | N/A |
| Completed | Implementing Hypertension Screening Guidelines in Primary Care NCT03480217 | Columbia University | N/A |
| Completed | An Observational Study to Evaluate Effectiveness and Safety of Amosartan Plus Tablet NCT05462535 | Hanmi Pharmaceutical Company Limited | — |
| Completed | Association Between Coronary Flow Reserve and BH4 Levels in High CV Risk NCT03841383 | IRCCS San Raffaele | — |
| Terminated | Peripheral Vascular Effects of Sulfhydryl-containing Antihypertensive Pharmacotherapy on Microvessels in Human NCT03179163 | Penn State University | Phase 1 / Phase 2 |
| Unknown | Potential Associated Factors of Uncontrolled Hypertension NCT02723643 | Guangdong Provincial People's Hospital | — |
| Unknown | First-In-Human Study Evaluating a Novel Catheter Device in Subjects With Treatment-Resistant Hypertension NCT03314012 | Cibiem, Inc. | N/A |
| Completed | Diagnosis of Hypertension by Home Blood Pressure Monitoring NCT03855605 | DongGuk University | — |
| Completed | Antiplatlet Effects of Standardized Tomato Extract in Hypertensive Subjects NCT03206944 | Beata Krasinska | Phase 4 |
| Terminated | Cardiovascular Effects of Angiotensin (1-7) in Essential Hypertension NCT02245230 | Vanderbilt University | Phase 1 |
| Completed | Reduction of Left Ventricular Hypertrophy After Eplerenone Therapy NCT03186742 | Poznan University of Medical Sciences | Phase 4 |
| Completed | Pharmacological and Nonpharmacological Factors That Contribute Blood Pressure Control NCT05513430 | Maltepe University | — |
| Completed | Efficacy and Safety of Fimasartan Alone or Combined With HCTZ in Mexican Patients With Essential Hypertension NCT02466490 | Stendhal Americas, S.A. | Phase 3 |
| Completed | Use of Metabolomics to Differentiate the Antihypertensive Effect of Acupuncture From Sham Acupuncture in Hyper NCT03492892 | The University of Hong Kong | N/A |
| Completed | Pivotal Bioequivalence FDC Nifedipine / Candesartan vs. Loose Combination of Single Components, Fed NCT01350609 | Bayer | Phase 1 |
| Completed | Study of Nifedipine GITS and Candesartan Combination Compared to Monotherapy in Patients With Essential Hypert NCT01303783 | Bayer | Phase 2 |
| Completed | Single Dose Bioequivalence Study Comparing Nifedipine/Candesartan FDC (Fixed Dose Combination) With Loose Comb NCT01227603 | Bayer | Phase 1 |
| Completed | Sympathetic Activity and Cardiometabolic Complications NCT04495231 | University of Turin, Italy | — |