Trials / Completed
CompletedNCT03503773
The TARGET BP OFF-MED Trial
A Phase 2, Multicenter, Blinded, Sham Procedure-Controlled Trial of Renal Denervation by the Peregrine System Kit, in Subjects With Hypertension, in the Absence of Antihypertensive Medications
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 350 (actual)
- Sponsor
- Ablative Solutions, Inc. · Industry
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
To obtain an assessment of the efficacy and safety of renal denervation by alcohol-mediated neurolysis using the Peregrine Kit in hypertensive subjects in the absence of antihypertensive medications.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Alcohol | Alcohol is directly infused/delivered to the adventitial and periadventitial space of the renal arteries |
| OTHER | Sham control | endovascular, renal angiography |
Timeline
- Start date
- 2018-09-24
- Primary completion
- 2022-01-31
- Completion
- 2024-01-10
- First posted
- 2018-04-20
- Last updated
- 2025-05-14
- Results posted
- 2024-10-04
Locations
4 sites across 4 countries: Belgium, France, Germany, United Kingdom
Source: ClinicalTrials.gov record NCT03503773. Inclusion in this directory is not an endorsement.