NCT06019598

Licorice and Home Blood Pressure, Additional Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 3 (actual)
• Sponsor: Linkoeping University · Other Government
• Sex: All
• Age: 18 Years – 31 Years
• Healthy volunteers: Accepted

Summary

Out-of-office blood pressure is more strongly associated with cardiovascular risk than office blood pressure. Licorice is known to raise blood pressure, but no previous studies have measured the effects on home blood pressure. The aim of this study is to analyze the association between licorice intake and home blood pressure.

Detailed description

For a detailed background, please see Clinical Trials registration number NCT05661721. In brief, out-of-office blood pressure is more strongly associated with cardiovascular risk than office blood pressure. Licorice is known to raise blood pressure, but no previous studies have measured the effects on home blood pressure. In a previous study, the response to licorice intake varied between participants. The aim of this study is to analyze the response of the most "licorice sensitive" quartile of participants from the original study to lower dosages of licorice, corresponding to 20 and 50 milligram och GA daily.

Conditions

• Hypertension,Essential

Interventions

Type	Name	Description
OTHER	Licorice	Ecologic sweet licorice pastilles made from Glycyrrhiza glabra grown in Calabria, Italy, with a GA content of 29.9 ±2.0 mg/g.

Timeline

• Start date: 2023-09-19
• Primary completion: 2024-02-24
• Completion: 2024-08-13
• First posted: 2023-08-31
• Last updated: 2024-10-09

Locations

1 site across 1 country: Sweden