NCT03778489

Impact of Aerobic Exercise Training on Sympathetic Vasoconstriction and Vascular Function in Essential Hypertension

Impact of Aerobic Exercise Training on Sympathetically Mediated Vasoconstriction and Vascular Function in Individuals With Essential Hypertension (IMPROVEH)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: University of Copenhagen · Academic / Other
• Sex: All
• Age: 35 Years – 65 Years
• Healthy volunteers: Accepted

Summary

Sympathetic nervous activity plays an important role in the development of hypertension and studies have shown that the pannexin-1 channel is involved in the signalling of the sympathetic activity to the vascular bed. The main project aim is to investigate the effects of 10 weeks of high intensity training on the effect of the sympathetic nervous activity on vascular function in individuals with essential hypertension. A secondary aim is to assess the role of essential hypertension and physical activity on vascular endothelial function,

Conditions

• Hypertension,Essential

Interventions

Type	Name	Description
OTHER	Training	10 weeks of high intensity exercise training. 2-3 trainings per week of approx. 40 min.

Timeline

• Start date: 2019-02-19
• Primary completion: 2022-11-01
• Completion: 2022-11-01
• First posted: 2018-12-19
• Last updated: 2022-11-02

Locations

1 site across 1 country: Denmark