| Suspended | Phase 2 Study to Assess Efficacy & Safety of WP1302 Prevent Relapse of MMI w/Draw in Subj. w/ Graves' dz NCT06240455 | Worg Biotherapeutics Inc. | Phase 2 |
| Recruiting | Systemic Inflammation, Thyroid Autoimmunity and Neuroretinal Changes in Graves Disease NCT07480720 | Elazıg Fethi Sekin Sehir Hastanesi | — |
| Recruiting | Impact of Thyroid Hormones on Human Glucose and Energy Metabolism NCT07410637 | University of Ulm | N/A |
| Not Yet Recruiting | Telehealth Music Therapy for Adults With Endocrine Disorder and Depression NCT07413874 | Appalachian State University | N/A |
| Recruiting | In Vivo CAR-T for Refractory Graves' Disease NCT07333677 | Shanghai Zhongshan Hospital | EARLY_Phase 1 |
| Enrolling By Invitation | A Long-Term Extension Study of IMVT-1402 in Adult Participants With Graves' Disease (GD) NCT07286006 | Immunovant Sciences GmbH | Phase 2 |
| Recruiting | Allogeneic Anti-CD19/BCMA CAR-T for Refractory Graves' Disease NCT07261345 | Shanghai Zhongshan Hospital | EARLY_Phase 1 |
| Recruiting | NEXUS Study: A Study to Test Single and Multiple Doses of MER511 Given to Adults With Graves' Disease NCT07305818 | Merida Biosciences | Phase 1 |
| Recruiting | A Study of GensSci098 in Subjects With Graves' Disease NCT07286656 | Changchun GeneScience Pharmaceutical Co., Ltd. | Phase 1 |
| Recruiting | Thyroid Artery Goitre Embolization Trial A Pilot Study Investigating Thyroid Artery Embolisation as a Treatmen NCT07046546 | Royal Berkshire NHS Foundation Trust | N/A |
| Recruiting | A Study to Investigate the Efficacy and Safety of Rilzabrutinib in Adult Participants With Graves' Disease NCT06984627 | Sanofi | Phase 2 |
| Recruiting | Prospective Evaluation of OptiThyDose NCT06864351 | University Children's Hospital Basel | N/A |
| Recruiting | Study of BHV-1300 in Graves' Disease NCT06980649 | Biohaven Therapeutics Ltd. | Phase 1 |
| Recruiting | Allogeneic Anti-CD19 CAR-T for Refractory Graves' Disease NCT07129642 | Shanghai Zhongshan Hospital | EARLY_Phase 1 |
| Recruiting | Impact of Vitamin D Therapy on Thyroid Function and Antibody Levels in Pediatric Graves' Disease NCT07369063 | Northwell Health | Phase 2 |
| Recruiting | Prevalence and Predictors of Incidental Thyroid Carcinoma in Patients With Graves' Disease Undergoing Thyroide NCT07059507 | Minia University | — |
| Recruiting | Thyroidectomy for Graves' Disease or Amiodarone-induced Thyrotoxicosis NCT06963203 | Andrea Goldmann | — |
| Not Yet Recruiting | Evaluating an AI Tool for Detecting Thyrotoxic States NCT07017907 | THYROSCOPE INC. | — |
| Recruiting | A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With NCT07018323 | Immunovant Sciences GmbH | Phase 2 |
| Recruiting | A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With NCT06727604 | Immunovant Sciences GmbH | Phase 2 |
| Not Yet Recruiting | Methimazole in Graves' Disease - Comparing the Computer-aided Treatment DigiThy Versus Usual Care NCT06327828 | Medical University of Graz | N/A |
| Not Yet Recruiting | Role of Embolization of Thyroid Arteries as a Treatment for Different Thyroid Disorders NCT06537141 | Assiut University | N/A |
| Not Yet Recruiting | Assessment of Thyroid Doppler Ultrasound in Followup of Pediatric Graves' Disease NCT06357494 | Assiut University | — |
| Not Yet Recruiting | Iodine Supplementation in Graves' Hyperthyroidism NCT06540469 | Shandong Provincial Hospital | N/A |
| Not Yet Recruiting | Graves' Disease Induced by Epstein-Barr Virus Lytic Reactivation NCT06426758 | Xiao-Ming Mao | — |
| Recruiting | The Impact of Person Centred Care (PCC) in Grave's Disease NCT06309316 | Vastra Gotaland Region | N/A |
| Active Not Recruiting | BASE-DIET: a Study on Nutritional Intervention in Patients With Graves' Disease NCT06921304 | Istituti Clinici Scientifici Maugeri SpA | N/A |
| Recruiting | Graves' Disease Remission Study: MycoMeth Combo NCT06068179 | The First Affiliated Hospital of Xiamen University | Phase 2 / Phase 3 |
| Recruiting | Course for Brain Fatigue After Graves' Disease Controlled Study NCT06134219 | Vastra Gotaland Region | N/A |
| Completed | Exploring Accessible Beauty for Individuals With Upper Extremity Deficits NCT05945784 | Casa Colina Hospital and Centers for Healthcare | — |
| Recruiting | A Prospective Evaluation of Microwave Ablation (MWA) in the Treatment of Relapsed Graves' Disease NCT06506149 | The University of Hong Kong | N/A |
| Recruiting | Preoperative Corticosteroids in Autoimmune Thyroid Disease NCT05435547 | Indiana University | Phase 4 |
| Completed | A Proof-of-Concept Study to Assess Batoclimab in Participants With Graves' Disease NCT05907668 | Immunovant Sciences GmbH | Phase 2 |
| Unknown | To Investigate the Effect of 2019 Novel Coronavirus Infection on the Condition of Patients With Hyperthyroidis NCT06204393 | Qilu Hospital of Shandong University | — |
| Active Not Recruiting | Incidence of Graves' Disease After COVID-19 Vaccination NCT07213141 | Laura ICONARU | — |
| Withdrawn | Prospective, Observational Study on the Carotid Intima-media Thickness in Patients Undergoing Thyroid Surgery NCT05774535 | Istituto Auxologico Italiano | — |
| Unknown | Three-dimensional Ultrasonography Thyroid Volume Measurement. NCT05510609 | Rigshospitalet, Denmark | N/A |
| Terminated | Efficacy of Methimazole Dosing Algorithm NCT05964452 | Cook County Health | — |
| Completed | TSI and Its Relationship With Graves' Disease Relapse NCT05713097 | University of Medicine and Pharmacy at Ho Chi Minh City | — |
| Recruiting | Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Init NCT05635266 | Sanguine Biosciences | — |
| Active Not Recruiting | Cardiac Symptoms in Patients With Treated Graves' Disease NCT06908369 | Ulla Feldt-Rasmussen | — |
| Completed | Resting Heart Rate Monitoring for Optimized Treatment and Surveillance of Hyperthyroidism NCT04932135 | University Hospital, Basel, Switzerland | — |
| Recruiting | The Effect of Teprotumumab on Thyroid Eye Disease and Thyroid Dysfunction NCT06275373 | Walter Reed National Military Medical Center | — |
| Unknown | Additional Autoimmune Diseases With Type 1 Diabetes in Pediatrics at Diabetes Diagnosis and During Follow-up NCT04789993 | Central Hospital, Nancy, France | — |
| Completed | Effects of Vitamin D Supplementation on Muscle Function Among Grave's Disease Patients NCT06451016 | Frontier Medical and Dental College, Abbotabad | N/A |
| Completed | Analysis of BPA Concentration in Serum in Women of Reproductive Age With Autoimmune Thyroid Disease NCT04682340 | Jagiellonian University | — |
| Completed | The Epidemiology, Management, and the Associated Burden of Related Conditions in Alopecia Areata NCT04239521 | Momentum Data | — |
| Completed | Change of Gut Microbiome in the Treatment of Graves' Disease NCT04383795 | Seoul St. Mary's Hospital | — |
| Recruiting | Exploring Immunological Markers Associated With Mental Fatigue in Graves' Disease NCT05678374 | Vastra Gotaland Region | — |
| Recruiting | Validating Immunological Markers Associated With Mental Fatigue in Graves' Disease NCT06081439 | Vastra Gotaland Region | — |
| Completed | Diagnostic Accuracy Study of Indocyanine Green for Parathyroid Perfusion Assessment NCT03969108 | University Health Network, Toronto | Phase 4 |
| Completed | Effect of Hyperthyroidism and Its Treatment in Graves' Disease to Early Marker of Atherosclerosis NCT05118542 | Indonesia University | Phase 3 |
| Recruiting | Personalized Treatment in Thyroid Disorders NCT03517579 | Johns Hopkins University | N/A |
| Unknown | The Relationship Between NK Cell and Graves' Disease NCT04135573 | Shandong Provincial Hospital | — |
| Completed | Anti-insulin-like Growth Factor-1 Receptor (IGF-1R) Antibodies in Graves' Disease and Graves' Orbitopathy NCT03498417 | University of Pisa | — |
| Recruiting | Effects of Different Treatment Schemes on the Regulation and Recurrence of Graves' Disease NCT05461820 | The First Affiliated Hospital with Nanjing Medical University | Phase 4 |
| Unknown | Efficacy and Safety of Cholestyramine and Prednisolone as Adjunctive Therapy in Treatment of Overt Hyperthyroi NCT03303053 | Clinical Research Centre, Malaysia | Phase 3 |
| Completed | HIFU vs RAI in the Relapsed Graves' Disease NCT03013257 | The University of Hong Kong | N/A |
| Unknown | Total Thyroidectomy Versus Thionamides in Patients With Moderate-to-Severe Graves' Ophthalmopathy NCT03066076 | Medical University of Vienna | Phase 3 |
| Completed | Clinical Application of Pulse Rate-monitoring Activity Trackers in Thyrotoxicosis NCT03009357 | Seoul National University Bundang Hospital | — |
| Completed | ATX-GD-59 in Patients With Graves Disease Not Treated With Anti-thyroid Therapy NCT02973802 | Apitope International NV | Phase 1 |
| Completed | K1-70 - A Study in Subjects With Graves' Disease NCT02904330 | AV7 Limited | Phase 1 |
| Completed | A Study to Evaluate the Safety and Effect of CFZ533 on Patients With Graves' Disease NCT02713256 | Novartis Pharmaceuticals | Phase 2 |
| Completed | D-vitamin And Graves' Disease; Morbidity And Relapse Reduction NCT02384668 | University of Aarhus | N/A |
| Terminated | Does Potassium Iodide (SSKI) Reduce Vascularity in Graves' Thyroidectomy? NCT04080505 | Columbia University | Phase 3 |
| Unknown | Role of the Microbiome in Graves' Orbitopathy NCT02373995 | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | Phase 1 / Phase 2 |
| Completed | DNA Methylation and Autoimmune Thyroid Diseases NCT02491567 | Aristotle University Of Thessaloniki | — |
| Unknown | Next-generation Sequencing (NGS) of Peripheral Blood Immune Repertoire in Graves' Disease NCT02210741 | National Taiwan University Hospital | — |
| Completed | Thyroid Disorders in Malaysia: A Nationwide Multicentre Study NCT02190214 | International Islamic University Malaysia | — |
| Completed | Effects Of Oral Alfacalcidol On Maturation Of Dendritic Cells In Graves' Disease Patients NCT02993302 | Dr Cipto Mangunkusumo General Hospital | Phase 2 |
| Unknown | Doxycycline Treatment in Mild Thyroid-Associated Ophthalmopathy NCT02203682 | Sun Yat-sen University | Phase 2 |
| Completed | Study of the Efficacy of Local Analgesia as an Adjunct to General Anesthesia in Thyroidectomy and Parathyroide NCT02205801 | University of Chicago | N/A |
| Completed | Treatment of Graves' Hyperthyroidism With Selenium Plus Methimazole NCT02727738 | University of Pisa | N/A |
| Completed | Early Levothyroxine Post Radioactive Iodine NCT01950260 | Mayo Clinic | Phase 2 / Phase 3 |
| Unknown | Comparative Study of Different I-131 Doses in Graves' Disease NCT02114619 | Mashhad University of Medical Sciences | N/A |
| Completed | Post-Radioiodine Graves' Management: The PRAGMA-Study NCT01885533 | Newcastle-upon-Tyne Hospitals NHS Trust | — |
| Completed | Shared Decision Making in Graves Disease - Graves Disease (GD) Choice NCT02107794 | Mayo Clinic | N/A |
| Recruiting | A Clinical Follow-up Study on Drug Therapy for Graves' Disease Patients in China NCT07040306 | First Hospital of China Medical University | — |
| Completed | Efficacy of Subantimicrobial Dose Doxycycline for Moderate to Severe and Active Graves' Orbitopathy NCT01727973 | Sun Yat-sen University | Phase 1 / Phase 2 |
| Unknown | Bupivacaine Injection of Eye Muscles to Treat Strabismus NCT01616108 | Smith-Kettlewell Eye Research Institute | Phase 2 / Phase 3 |
| Completed | Function of Regulatory T Cells Improved by Dexamethasone in Graves' Patients NCT01534169 | Xiao-Ming Mao | Phase 1 |
| Completed | Liver Function After Intravenous Methylprednisolone Administration NCT03667157 | Medical University of Warsaw | Phase 4 |
| Terminated | Trial Comparing Complication Rates Associated With Robot-assisted Thyroidectomy to External Thyroidectomy NCT01320813 | Centre Hospitalier Universitaire de Nīmes | N/A |
| Unknown | Thyroid Disease and Personality Study NCT02620085 | National Taiwan University Hospital | — |
| Completed | Characteristics of Islet β-cell Functions in Chinese Patients With Graves' Disease NCT02376088 | Weikai Hou | — |
| Completed | Coagulation After Intravenous Methylprednisolone Administration NCT03535090 | Piotr Miskiewicz | — |
| Completed | Impact of Intravenous Methylprednisolone Treatment on Blood Pressure NCT03590080 | Medical University of Warsaw | — |
| Completed | Heart Rhythm After Intravenous Methylprednisolone Administration NCT04391439 | Medical University of Warsaw | — |
| Completed | Prevalence of Circulating Parvovirus Genome in Recently Diagnosed Graves' Disease: a Case-control Study NCT02798965 | Centre Hospitalier Universitaire, Amiens | N/A |
| Completed | Radioactive Iodide Therapy for Pediatric Graves' Disease NCT01269749 | University of Florida | Phase 2 |
| Completed | Differential Diagnosis of STA-PSV in Thyrotoxicosis NCT01227499 | xiaolong zhao | — |
| Completed | Evaluation of Optimal Time of Methimazole Discontinuation Before Radio-iodine Therapy in Hyperthyroid Grave's NCT01560299 | Mashhad University of Medical Sciences | N/A |
| Unknown | Application of Digital Infrared Thermal Imaging (DITI) in Graves' Disease NCT01182584 | National Taiwan University Hospital | — |
| Completed | Autoimmune Thyroid Disease Genetic Study NCT00958113 | University of Colorado, Denver | — |
| Completed | Predictive Genetic Risk Assessment Trial NCT00782366 | Mayo Clinic | — |
| Completed | Remission Induction and Sustenance in Graves' Disease 2 NCT00796913 | Aalborg University Hospital | N/A |
| Completed | Low Doses of Cholestyramine in the Treatment of Hyperthyroidism NCT00677469 | Shiraz University of Medical Sciences | N/A |
| Completed | Color Doppler Imaging of Orbital Venous Flow in Grave's Orbitopathy NCT00697528 | University of Sao Paulo | — |
| Completed | Is the Routine Pressure Dressing After Thyroidectomy Necessary? NCT00400465 | Khon Kaen University | Phase 4 |
| Completed | Adjuvant Treatment of Graves´ Ophthalmopathy With NSAID (aGO Study) NCT01458600 | Mikael Lantz | Phase 4 |
| Completed | Effect of Lugol's Solution in the Patients With Graves' Disease NCT00432146 | Istanbul University | — |
| Completed | TSH Receptor Antibody Heterogeneity in Children and Adolescents With Graves' Disease NCT00335062 | Boston Children's Hospital | — |
| Completed | Impact of SSKI Pre-Treatment on Blood Loss in Thyroidectomy for Graves Disease NCT00946296 | University of Massachusetts, Worcester | Phase 4 |
| Completed | Prevention Relapse of Graves' Disease by Intrathyroid Injection of Dexamethasone NCT00917241 | Xiao-Ming Mao | Phase 4 |
| Completed | Rituximab in the Treatment of Graves' Disease NCT00150111 | Odense University Hospital | Phase 1 / Phase 2 |
| Completed | Antithyroid Drugs During Radioiodine Therapy NCT00150137 | Odense University Hospital | Phase 4 |
| Completed | Block-replacement Therapy During Radioiodine Therapy NCT00150124 | Steen Bonnema | Phase 4 |
| Completed | rhTSH, Thyroid Size, and Radioiodine Therapy in Benign Goiter NCT00145366 | Odense University Hospital | Phase 2 |
| Completed | Genetic Polymorphisms Associated With Cigarette Smoking and Risk of Graves' Disease NCT00505011 | University of Campinas, Brazil | — |
| Completed | Comparison of Different Doses of 131I in Severe Graves' Hyperthyroidism NCT01039818 | Hospital de Clinicas de Porto Alegre | Phase 3 |
| Completed | Effective Iodide Therapy for Untreated Patients With Graves' Hyperthyroidism Avoiding Thionamide Drugs With Ma NCT04686006 | Kyushu University | — |
| Completed | Spontaneous Coronary Artery Dissection (SCAD) and Autoimmunity NCT03941184 | Mayo Clinic | — |
| Completed | Randomized Study of Sequential Orbital Radiotherapy for Graves' Ophthalmopathy NCT00004660 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | N/A |