NCT01560299

Evaluation of Optimal Time of Methimazole Discontinuation Before Radio-iodine Therapy in Hyperthyroid Grave's Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 150 (actual)
• Sponsor: Mashhad University of Medical Sciences · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Iodine therapy is the best treatment for graves disease.Most patients receive methimozale prior to radio-iodine treatment. This may decrease treatment response to iodine therapy. Some physicians advice to discontinue methimazole 3 days before radioiodine therapy and others prefer longer off - methimazole period which bothers most patients. This study aimed to evaluate optimum time for methimazole discontinuation in graves disease.

Conditions

• Graves Disease

Interventions

Type	Name	Description
DRUG	Methimazole	Methimazole was stopped 24-48 before radio-iodine therapy
DRUG	Methimazole	methimazole discontinued 49-72 hours before radioiodine treatment
DRUG	Methimazole	methimazole discontinued 73-168 hours before radio-iodine treatment

Timeline

• Start date: 2010-02-01
• Primary completion: 2012-01-01
• Completion: 2012-01-01
• First posted: 2012-03-22
• Last updated: 2012-03-22

Locations

1 site across 1 country: Iran