Clinical Trials Directory

Trials / Terminated

TerminatedNCT05964452

Efficacy of Methimazole Dosing Algorithm

The Efficacy of Cook County Health's Methimazole Dosing Algorithm in the Setting of Ne Onset Graves' Hyperthyroidism

Status
Terminated
Phase
Study type
Observational
Enrollment
11 (actual)
Sponsor
Cook County Health · Other Government
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

To prospectively study the efficacy and safety of the Cook County Health (CCH) methimazole (MMI) dosing algorithm in the setting of new onset Graves' disease.

Detailed description

To conduct a prospective observational study in 60 patients with newly diagnosed Graves' disease who are either methimazole naive or who have been initiated on MMI within previous 4-6 weeks per CCH algorithm and assess for efficacy and safety of MMI dosing administered. Study group size is based on 90% power and projected efficacy of 70% patients reaching target.

Conditions

Interventions

TypeNameDescription
DRUGMethimazole TabletsTesting dosing algorithm for efficacy.

Timeline

Start date
2022-02-14
Primary completion
2024-09-17
Completion
2024-09-17
First posted
2023-07-28
Last updated
2024-12-27

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT05964452. Inclusion in this directory is not an endorsement.

Efficacy of Methimazole Dosing Algorithm (NCT05964452) · Clinical Trials Directory