NCT05435547

Preoperative Corticosteroids in Autoimmune Thyroid Disease

Randomized Controlled Trial of Preoperative Corticosteroids in Autoimmune ThyroidDisease

• Status: Recruiting
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 76 (estimated)
• Sponsor: Indiana University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study proposes to randomize patients about to undergo surgery for their autoimmune, inflammatory thyroid disease, and determine if a short course of corticosteroids decreases the inflammation of the gland and makes surgery less difficult.

Conditions

• Graves Disease
• Hashimoto Disease

Interventions

Type	Name	Description
DRUG	Dexamethasone	Will take Dexamethasone pre-operatively
DRUG	Placebo	Will take Placebo pre-operatively

Timeline

• Start date: 2023-06-16
• Primary completion: 2026-06-30
• Completion: 2026-12-30
• First posted: 2022-06-28
• Last updated: 2025-05-01

Locations

3 sites across 1 country: United States

Regulatory

• FDA-regulated drug study