| Not Yet Recruiting | Safety and Performance of the Novalung Ultimate Kit and Xenios 2.0 During Stationary Use in Hospital and Groun NCT07156669 | Xenios AG | — |
| Recruiting | Evaluating the Safety and Performance of the MiniLung Petite Kit in Neonatal and Pediatric Patients With Acute NCT06750536 | Xenios AG | — |
| Not Yet Recruiting | RECOMMEND Platform Trial NCT06526533 | Australian and New Zealand Intensive Care Research Centre | Phase 3 |
| Recruiting | "Continuous Positive Airway Pressure on Venovenous extracorporeaL Membrane Oxygenation for Acute respIratory D NCT06814340 | Assistance Publique - Hôpitaux de Paris | Phase 3 |
| Not Yet Recruiting | Pharmacokinetics and Modelling of Beta-Lactam in ECMO-VA Patients NCT06338345 | University Hospital, Grenoble | N/A |
| Recruiting | ECMO ABI Detection With Hyperfine NCT06469801 | Children's Mercy Hospital Kansas City | N/A |
| Recruiting | Use of Nafamostat Mesilate for Anticoagulation in Patients With ECMO NCT06276010 | Xiaotong Hou | N/A |
| Recruiting | Use of Bivalirudin for Anticoagulation in Patients With Extracorporeal Membrane Oxygenation NCT06275555 | Xiaotong Hou | N/A |
| Not Yet Recruiting | The Usefulness of Myocardial Work IndeX in ExtraCorporeal Membrane Oxygenation Patients NCT05838937 | Semmelweis University Heart and Vascular Center | — |
| Recruiting | BivaLirudin versUS Heparin in Extracorporeal Membrane Oxygenation NCT05959252 | Sydney Local Health District | Phase 2 |
| Not Yet Recruiting | PK/PD Study of Anti-Infective Drugs in Critically Ill Patients Receiving Extracorporeal Membrane Oxygenation T NCT06319677 | The Third Xiangya Hospital of Central South University | — |
| Recruiting | ECMO LEft Ventricle UNloading Strategy NCT06766006 | Maastricht University Medical Center | — |
| Recruiting | Cangrelor on Top of anticoagUlation in Patients With myocaRdial Infarction-related Cardiogenic Shock/Cardiac A NCT06792643 | IRCCS San Raffaele | Phase 2 |
| Recruiting | Continuous Compartment Pressure Monitoring for Compartment Syndrome in VA-ECMO Patients NCT05830721 | Johns Hopkins University | N/A |
| Completed | ECMO Hemostatic Transfusions in Children NCT05796557 | Yale University | Phase 4 |
| Completed | Evaluation of Long-term Quality of Life in Children Supported with ExtraCorporeal Membrane Oxygenation (ECMO) NCT05721105 | Nantes University Hospital | — |
| Recruiting | Red Blood Cell Transfusion in ECMO - A Feasibility Trial NCT05814094 | Australian and New Zealand Intensive Care Research Centre | N/A |
| Completed | Definition and Management of Right Ventricular Injury in Adult Patients Receiving Extracorporeal Membrane Oxyg NCT05948332 | Prashant Nasa | — |
| Completed | Low-Field Bedside Brain Magnetic Resonance Imaging in Pediatric Extracorporeal Membrane Oxygenation NCT06074406 | Children's Mercy Hospital Kansas City | N/A |
| Completed | Impact of ECMO Cannula Chlorhexidine-impregnated Dressings to Decrease Extracorporeal Membrane Oxygenation-can NCT05750576 | Assistance Publique - Hôpitaux de Paris | N/A |
| Unknown | Evaluation of eCPR Survivors NCT05339854 | Charite University, Berlin, Germany | — |
| Recruiting | DIC Markers and Thrombin Generation Parameters in Patients on ECMO Support: a Pilot Study NCT06095518 | Queen Mary Hospital, Hong Kong | — |
| Recruiting | Platform of Randomized Adaptive Clinical Trials in Critical Illness NCT05440851 | University Health Network, Toronto | N/A |
| Recruiting | Distal Perfusion Timing, Early or Conservative, to Prevent Limb Ischemia During Peripheral VA-ECMO NCT05698628 | Min-Seok Kim | N/A |
| Unknown | Comparison of Four Intensive Care Scores in Prediction of VA-ECMO Survival. NCT05730881 | Hamad Medical Corporation | — |
| Unknown | Efficacy and Clinical Outcomes of Levosimendan in E-CPR NCT05730907 | Hamad Medical Corporation | — |
| Unknown | Evaluation of the 1-year Prognosis of Patients Under Veno-arterial Extracorporeal Membrane Oxygenation for Car NCT05696210 | Central Hospital, Nancy, France | — |
| Recruiting | Nosocomial Infections in ECMO Patients NCT05566665 | Policlinico Hospital | — |
| Completed | Correlation Between PaCO2 and Respiratory Effort in Patients With COVID-19 With Extracorporeal Membrane Oxygen NCT05882474 | Peking Union Medical College Hospital | — |
| Active Not Recruiting | The ECMO-Free Trial NCT05486559 | Vanderbilt University Medical Center | N/A |
| Unknown | Effects of Induced Moderate Hypothermia on ARDS Patients Under Venovenous ExtraCorporeal Membrane Oxygenation NCT05306392 | Central Hospital, Nancy, France | N/A |
| Recruiting | Anticoagulation-free VV ECMO for Acute Respiratory Failure NCT04273607 | Damian Ratano | Phase 2 / Phase 3 |
| Completed | Therapy and Outcome of Prolonged Veno-venous ECMO Therapy of Critically Ill ARDS Patients. NCT05338593 | Goethe University | — |
| Active Not Recruiting | Early Rehabilitation in Patients on Extracorporeal Membrane Oxygenation NCT05003609 | Australian and New Zealand Intensive Care Research Centre | N/A |
| Unknown | ECMELLA vs. ECMO on 30-day Mortality NCT05175898 | Charite University, Berlin, Germany | — |
| Recruiting | EUROSETS ECMO Study in Clinical Extracorporeal Life Support Applications NCT05163925 | Eurosets S.r.l. | — |
| Recruiting | Monitoring of Cerebral Blood Flow in Patients on Extracorporeal Membrane Oxygenation NCT05303363 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | — |
| Completed | Assessing Brain Injury Using Portable Magnetic Resonance Imaging (MRI) NCT05469139 | Johns Hopkins University | — |
| Completed | Safety and Feasibility of Argatroban As Anticoagulant in Adults with ECMO NCT05226442 | Medical University of Vienna | Phase 2 / Phase 3 |
| Unknown | PREdiCtIon of Weanability, Survival and Functional outcomEs After ECLS NCT05444764 | UMC Utrecht | — |
| Unknown | Registry Study of Extracorporeal Cardiopulmonary Resuscitation (eCPR) in China NCT04956497 | Peking Union Medical College Hospital | — |
| Completed | LEVOSIMENDAN to Facilitate Weaning From ECMO in Severe Cardiogenic Shock Patients NCT04728932 | Assistance Publique - Hôpitaux de Paris | Phase 3 |
| Unknown | Cerebral Bleeding in COVID-19 ARDS Patients on Veno-venous ECMO NCT04853953 | University of Zurich | — |
| Completed | Quality of Life 1y and 2 y After VV-ECMO for COVID-19 NCT05780255 | University Hospital, Ghent | — |
| Withdrawn | Bivalirudin vs Heparin in ECMO Patients NCT03707418 | Johns Hopkins University | Phase 1 |
| Unknown | Application of Early Physical Therapy Regimens in Patients With Veno-venos Extracorporeal Membrane Oxygenation NCT04918498 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Unknown | Protecting Brains and Saving Futures - the PBSF Protocol NCT03786497 | Protecting Brains Saving Futures | — |
| Completed | Impact of Extra Corporal Membrane Oxygenation Services on Burnout Development in Intensive Care Units. NCT04620005 | Hamad Medical Corporation | — |
| Recruiting | Study on the Efficacy and Timing of ECMO Therapy in Children With Refractory Septic Shock NCT03948048 | Children's Hospital of Fudan University | — |
| Unknown | Biomarkers, Genomics, Physiology in Critically Ill and ECMO Patients NCT04669444 | University of California, San Diego | N/A |
| Completed | Safety and Feasibility of Percutaneous Dilatational Tracheostomy in Patients With Severe COVID-19 Supported by NCT05045885 | Hamad Medical Corporation | — |
| Completed | Outcome of COVID-19 Patients After Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome NCT04383678 | Helsinki University Central Hospital | — |
| Unknown | Risk Factors Analysis for Acute Myocardial Infarction Patients NCT05390658 | Genglong Liu | — |
| Completed | Prospective Investigation of Antithrombin III Deficiency in Adult Patients With ECMO NCT04879550 | Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital | — |
| Completed | Evolution of Diaphragm Thickness Under Veno-arterial ECMO NCT04052230 | University Hospital, Grenoble | — |
| Terminated | Advanced Reperfusion Strategies for Refractory Cardiac Arrest NCT03880565 | University of Minnesota | N/A |
| Unknown | Safety and Efficacy of Bivalirudin Versus Heparin for Systemic Anticoagulation in Extracorporeal Membrane Oxyg NCT03965208 | Legacy Health System | Phase 4 |
| Unknown | D-dimer to Improve Anticoagulation Outcome During ECMO loNg-term supporteD NCT03261284 | Wuhan Asia Heart Hospital | N/A |
| Unknown | Predictors of Intracranial Hemorrhage in ARDS Patients on ECMO NCT04142775 | Charite University, Berlin, Germany | — |
| Unknown | Coagulation Monitoring in Patients on Extracorporeal Membrane Oxygenation (Observational Study) NCT03642912 | Ludwig-Maximilians - University of Munich | — |
| Completed | PRospective Multicenter Observational Study on Transfusion Practice in Vv-ECMO Patients: The PROTECMO Study NCT03815773 | The Mediterranean Institute for Transplantation and Advanced Specialized Therapies | — |
| Unknown | Does Extra-Corporeal Membrane Oxygenation Alter Antiinfectives Therapy Pharmacokinetics in Critically Ill Pati NCT04674657 | Royal Brompton & Harefield NHS Foundation Trust | — |
| Unknown | Estimation of Glomerular Filtration Flow in Patients of Resuscitation Under Extra-bodily Assistance NCT03525483 | University Hospital, Toulouse | N/A |
| Completed | Monitoring of Cerebral Autoregulation in Pediatric ECMO (ECMOX 1) NCT04282525 | Nantes University Hospital | — |
| Unknown | Extracorporeal Membrane Oxygenation Evaluated by Transcranial Doppler. NCT03457090 | University Hospital, Toulouse | N/A |
| Completed | Study Comparing Bivalirudin Versus Heparin in Neonatal and Pediatric ECMO NCT03318393 | University of Texas Southwestern Medical Center | Phase 4 |
| Completed | Extracorporeal Membrane Oxygenation Physical Training NCT03328767 | Australian and New Zealand Intensive Care Research Centre | N/A |
| Recruiting | Transplantation of Autologously Derived Mitochondria Following Ischemia NCT02851758 | Boston Children's Hospital | N/A |
| Withdrawn | Fixed Low-dose Heparin Versus Standard Adjusted-dose Heparin Infusion in Adults Receiving Venovenous ECMO With NCT02966080 | University of Arizona | N/A |
| Completed | The Effect of ECMO on the Pharmacokinetics of the Drugs and Their Clinical Efficacy NCT03659513 | University of Pennsylvania | — |
| Completed | Evaluation Of The Pharmacokinetics Of Antithrombin III In Neonates And Infants Undergoing CPB And ECMO Support NCT02631174 | Children's Hospital Medical Center, Cincinnati | Phase 1 |
| Completed | TEG Anticoagulation Monitoring During ECMO NCT02271126 | Policlinico Hospital | Phase 1 |
| Terminated | ECMO: Optimization of Its Use NCT02280460 | Renzo Loyaga Rendon | — |
| Completed | Evaluation of Coagulation Factors and Point-of-care Devices During Veno-venous ECMO Therapy NCT03754868 | University Hospital Goettingen | — |
| Completed | Echocardiographic Assessment of Function During ECMO Support NCT01551849 | Nationwide Children's Hospital | — |
| Recruiting | Post-Surgery Extracorporeal Life Support NCT04330651 | University of Florence | — |