NCT05175898

ECMELLA vs. ECMO on 30-day Mortality

Treatment With Leftventricular Impella® Micro-axial Pump and Veno-Arterial Extracorporeal Membrane Oxygenation (VA-ECMO) During Extracorporeal Cardiopulmonary Resuscitation (eCPR) on Mortality - An International Multicenter Cohort Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 60 (estimated)
• Sponsor: Charite University, Berlin, Germany · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This international, multicenter cohort study aims to investigate outcomes after treatment with extracorporeal cardiopulmonary resuscitation (eCPR) during cardiac arrest.

Detailed description

Left ventricular unloading with Impella® micro-axial pump has been shown to improve survival in patients with cardiogenic shock treated with veno-arterial extracorporeal membrane oxygenation (VA-ECMO). This study aims to investigate whether treatment with VA-ECMO and Impella ® (so called "ECMELLA") during extracorporeal cardiopulmonary resuscitation is associated with improved outcomes.

Conditions

• Cardiac Arrest
• Cardiopulmonary Arrest
• Extracorporeal Membrane Oxygenation Complication
• Cardiogenic Shock
• Acute Myocardial Infarction

Interventions

Type	Name	Description
DEVICE	VA-ECMO	Treatment with veno-arterial extracorporeal membrane oxygenation
DEVICE	ECMELLA	Treatment with veno-arterial extracorporeal membrane oxygenation plus Impella® micro-axial pump.

Timeline

• Start date: 2022-02-01
• Primary completion: 2022-10-01
• Completion: 2022-11-01
• First posted: 2022-01-04
• Last updated: 2022-01-04

Locations

1 site across 1 country: Germany