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UnknownNCT03642912

Coagulation Monitoring in Patients on Extracorporeal Membrane Oxygenation (Observational Study)

Coagulation Monitoring in Patients on Extracorporeal Membrane Oxygenation Hämostaseologisches Monitoring Bei Patienten Mit Extrakorporaler Membranoxygenierung

Status
Unknown
Phase
Study type
Observational
Enrollment
35 (actual)
Sponsor
Ludwig-Maximilians - University of Munich · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Coagulation disorders are on top of the list of extracorporeal-membrane oxygenation (ECMO) complications. They contribute significantly to morbidity and mortality of ECMO patients. This observational study aims to evaluate coagulation profiles of ECMO patients treated on the intensive care units of the Department of Anaesthesiology of LMU Munich.

Detailed description

Coagulation disorders are on top of the list of extracorporeal-membrane oxygenation (ECMO) complications. They contribute significantly to morbidity and mortality of ECMO patients. This observational study aims to evaluate coagulation profiles of ECMO patients treated on the intensive care units of the Department of Anaesthesiology of LMU Munich. Adult ECMO patients are included in the study after informed consent. Bleeding and thromboembolic complications as well as treatment details are recorded. Additional coagulation laboratory markers (such as von-Willebrand-factor, ADAMTS13-protease, platelet function tests and thromboelastometric tests) are correlated with clinical signs of bleeding. Regular ultrasound examination of the large vessels are performed to Screen for thrombosis.

Conditions

Timeline

Start date
2019-01-16
Primary completion
2020-09-30
Completion
2022-12-31
First posted
2018-08-22
Last updated
2022-04-06

Locations

1 site across 1 country: Germany

Source: ClinicalTrials.gov record NCT03642912. Inclusion in this directory is not an endorsement.