NCT04330651

Post-Surgery Extracorporeal Life Support

Outcomes' Predictors in Post-Surgery Extracorporeal Life Support

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 500 (estimated)
• Sponsor: University of Florence · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: —

Summary

Extracorporeal Life Support (ECLS) may provide pulmonary and circulatory support for patients with acute heart failure refractory to conventional medical therapy. However, indications and effectiveness of ECLS engagement post-surgery remains a concern. The investigators sought to analyze indications, modality and outcomes of PS-ECLS, to identify predictors of early and midterm survival after PS-ECLS. The investigators have recorded prospectively, and analysed data of 209 consecutive PS-ECLS patients between January 2004 and December 2018. Demographic and clinical data before, during and after PS-ECLS were collected and their influence on hospital mortality and outcomes (early and midterm) will analyse. Multivariate analysis of pre PS-ECLS implantation factors (as age, female sex , insulin-dependent diabetes, pulmonary hypertension, STS, type of surgical procedure data, pre-ECLS blood lactate level) will be made for identify prognostic risk factors of in-hospital mortality. Overall survival will be analysed, at 6 months,1-year and 5-years, respectively and the factors influencing mild/term outcome will be investigated.

Conditions

• Cardiogenic Shock
• Extracorporeal Life Support
• Extracorporeal Membrane Oxygenation Complication
• Post Cardiac Arrest Syndrome
• Post-cardiac Surgery

Interventions

Type	Name	Description
PROCEDURE	ECLS	Emergency application of Extracorporeal Life Support in post-surgical patients

Timeline

• Start date: 2004-01-01
• Primary completion: 2021-03-19
• Completion: 2029-01-31
• First posted: 2020-04-01
• Last updated: 2021-04-28

Locations

1 site across 1 country: Italy