| Not Yet Recruiting | Terazosin for Dementia With Lewy Bodies NCT04760860 | Qiang Zhang | Phase 1 / Phase 2 |
| Recruiting | Elucidating the Role of Cholinergic Degeneration in Cognitive Fluctuations in Lewy Body Dementia NCT07284290 | Virginia Commonwealth University | Phase 4 |
| Recruiting | tDCS Effect on Psychotic Symptoms in Dementia With Lewy Bodies (DLB), and Impacts on Caregiver Burden NCT06785948 | Association de Recherche Bibliographique pour les Neurosciences | N/A |
| Active Not Recruiting | DIAMOND-Lewy Guidelines for Antipsychotic Use in Older Patients NCT06357195 | Ohio State University | — |
| Not Yet Recruiting | How Does Pianistic Musical Training Influence the Development of Alzheimer's Disease? NCT06378372 | David Franco Castellanos | N/A |
| Active Not Recruiting | PERSEVERE: Peer Mentor Support and Caregiver Education in Lewy Body Dementia NCT06389032 | Rush University Medical Center | N/A |
| Recruiting | PET Imaging Evaluation of [11C]SY08 NCT06098612 | Massachusetts General Hospital | EARLY_Phase 1 |
| Recruiting | The Effect of Repetitive Transcranial Magnetic Stimulation on Cognitive Improvement in Dementia With Lewy Bodi NCT07122908 | Korea University Anam Hospital | Phase 1 / Phase 2 |
| Recruiting | Identification of Prodromal Neurodegeneration in Serotonergic-Induced REM Sleep Behavior Disorder NCT06467461 | University of Minnesota | N/A |
| Recruiting | [18F]-MFBG Versus [123I]-MIBG and [18F]-PE2I in PD vs. MSA and DLB vs. AD NCT06120049 | prof. dr. Koen Van Laere | Phase 2 / Phase 3 |
| Recruiting | Improving Prognostic Confidence in Neurodegenerative Diseases Causing Dementia Using Peripheral Biomarkers and NCT06529744 | University Health Network, Toronto | — |
| Completed | Family Caregiver Online Survey (Dementia and Swallowing Difficulties) NCT06471660 | University of Oregon | — |
| Active Not Recruiting | Environmental and Reproductive Health Risk for Lewy Body Dementia NCT06005935 | University of California, San Diego | — |
| Completed | RewinD-LB - Clinical Study of Neflamapimod in Patients With Dementia With Lewy Bodies NCT05869669 | EIP Pharma Inc | Phase 2 |
| Unknown | Implementation and Evaluation of Improved Access to Medical Imaging for Geriatric Patients of The Royal Ottawa NCT05428475 | Tim Lau | Phase 3 |
| Recruiting | Optical Neuroimaging and Cognition NCT05460143 | University of Cambridge | — |
| Completed | Cognitive Stimulation Therapy for Dementia: A Two-Armed Pragmatic Trial NCT05860127 | University of Massachusetts, Amherst | N/A |
| Completed | Speech Accessibility Project NCT05889260 | University of Illinois at Urbana-Champaign | — |
| Recruiting | Exploration of GCase Activity to Identify a Subpopulation Eligible for a Therapeutic Trial in Dementia With Le NCT05304195 | Assistance Publique - Hôpitaux de Paris | — |
| Active Not Recruiting | DIagnostic Biomarkers and Symptoms in Patients With Alzheimer's Disease and Lewy bodY Dementia NCT05768425 | Danish Dementia Research Centre | — |
| Completed | The Care Ecosystem Consortium Effectiveness Study NCT05669365 | University of California, San Francisco | N/A |
| Recruiting | Non-invasive Neurostimulation as a Tool for Diagnostics and Management for Neurodegenerative Diseases NCT05326750 | Kuopio University Hospital | N/A |
| Recruiting | North American Prodromal Synucleinopathy Consortium Stage 2 NCT05826457 | Washington University School of Medicine | — |
| Completed | Study to Evaluate the Safety, Tolerability and Efficacy of CT1812 in Subjects With Mild to Moderate Dementia W NCT05225415 | Cognition Therapeutics | Phase 2 |
| Active Not Recruiting | Community Outreach for Palliative Engagement -- Parkinson Disease NCT05222386 | University of Rochester | N/A |
| Recruiting | Comparing Antipsychotic Medications in LBD Over Time NCT05590637 | The University of Texas Health Science Center at San Antonio | Phase 4 |
| Completed | In Vivo PET of Synaptic Density in Cognitive Disorders NCT05384353 | Universitaire Ziekenhuizen KU Leuven | — |
| Completed | Neurological Soft Signs in Neurodegenerative Dementias NCT06354933 | University of Milano Bicocca | — |
| Terminated | ATH-1017 Treatment in Subjects With Parkinson's Disease Dementia or Dementia With Lewy Bodies (SHAPE Trial) NCT04831281 | LeonaBio | Phase 2 |
| Completed | Novel Diagnostic and Disease Stage Biomarkers in AD NCT05175664 | Danish Dementia Research Centre | — |
| Completed | WeCareAdvisor Study for Caregivers of People Living With Dementia NCT05012410 | Drexel University | N/A |
| Completed | Alpha tACS in Dementia With Lewy Bodies NCT05188105 | Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia | N/A |
| Completed | Development of an EEG Diagnostic for Alzheimer's Disease NCT04954183 | Mayo Clinic | — |
| Unknown | Trial of Ondansetron as a Parkinson's HAllucinations Treatment NCT04167813 | University College, London | Phase 2 |
| Completed | Palliative Care for Persons With Late-stage Alzheimer's and Related Dementias and Their Caregivers NCT04948866 | University of North Carolina, Chapel Hill | N/A |
| Completed | Optimization of Morphomer-based Alpha-synuclein PET Tracers NCT05067192 | Skane University Hospital | — |
| Completed | Clinical Feasibility of Speech Phenotyping for Remote Assessment of Neurodegenerative and Psychiatric Disorder NCT04939818 | Novoic Limited | — |
| Unknown | Ambroxol in New and Early DLB, A Phase IIa Multicentre Randomized Controlled Double Blind Clinical Trial NCT04588285 | Helse Fonna | Phase 2 |
| Unknown | Implication of Cognitive Reserve in Non-pharmacological Intervention Outcomes NCT06563453 | Masaryk University | N/A |
| Completed | Dementia With Lewy Bodies - Infinitome NCT04773041 | HealthPartners Institute | — |
| Unknown | Dementias and Microbiota Composition: Is Possible to Revert the Dementia Symptoms Reverting the Microbiota Com NCT05943925 | University Rovira i Virgili | — |
| Unknown | Virtual Individual Cognitive Stimulation Therapy: a Proof of Concept Study NCT04828434 | University College, London | N/A |
| Unknown | Advanced Cognitive Stimulation Therapy (ACST) NCT04550975 | University College, London | N/A |
| Completed | The PACE-DLB Study NCT04829656 | University of Florida | — |
| Completed | Self and Autobiographical Memory in Dementia With Lewy Bodies and Alzheimer Disease: a Behavioral and Multimod NCT04616287 | University Hospital, Strasbourg, France | N/A |
| Completed | Synuclein-One Study NCT04700722 | CND Life Sciences | — |
| Completed | Study to Evaluate a Potential PET Radioligand for Imaging Alpha-synuclein Deposits in the Brain NCT06445465 | Invicro | EARLY_Phase 1 |
| Recruiting | PUMCH Dementia Longitudinal Cohort Study NCT05023564 | Peking Union Medical College Hospital | — |
| Unknown | Exploring Biomarkers in Age Stratified PUMCH Dementia Cohort NCT04924361 | Peking Union Medical College Hospital | — |
| Completed | SAMi Intervention Study to Evaluate Smartwatch Interventions in Persons With MCI and Dementia NCT05885620 | University of Rostock | N/A |
| Completed | Learning to PERSEVERE: Peer Mentor Support and Caregiver Education in Lewy Body Dementia NCT04649164 | Rush University Medical Center | N/A |
| Unknown | Advanced Cognitive Stimulation Therapy Hong Kong (ACST-HK) NCT04555629 | University College, London | N/A |
| Recruiting | [18F]F-DOPA Imaging in Patients With Autonomic Failure NCT04246437 | Daniel Claassen | Phase 1 |
| Completed | Monitoring Anti-Dementia Drugs by Serum Levels NCT04117178 | Zealand University Hospital | Phase 4 |
| Completed | Visualising Cerebral and Peripheral Cholinergic Nerves in Patients With Dementia Lewy Bodies. NCT04291144 | University of Aarhus | — |
| Unknown | FDG Metabolism in Dementia With Lewy Body (DLB) Patients as Indicated by PET Dynamic Acquisition NCT04154215 | Tel-Aviv Sourasky Medical Center | N/A |
| Completed | Home-based Family Caregiver-delivered Music and Reading Interventions for People With Dementia NCT03907748 | Anglia Ruskin University | N/A |
| Active Not Recruiting | Trial of Parkinson's And Zoledronic Acid NCT03924414 | California Pacific Medical Center Research Institute | Phase 4 |
| Recruiting | ENhancing Outcomes in Cognitive Impairment Through Use of Home Sleep ApNea Testing NCT04335994 | Sunnybrook Health Sciences Centre | N/A |
| Recruiting | K0706 for Patients Diagnosed With Dementia With Lewy Bodies NCT03996460 | Georgetown University | Phase 2 |
| Withdrawn | A Study to Assess Safety, Tolerability, and Efficacy of HTL0018318 in Patients With Dementia With Lewy Bodies NCT03592862 | Nxera Pharma UK Limited | Phase 2 |
| Completed | Impact of Nilotinib on Safety, Tolerability, Pharmacokinetics and Biomarkers in Dementia With Lewy Bodies NCT04002674 | Georgetown University | Phase 2 |
| Completed | Impact of Bosutinib on Safety, Tolerability, Biomarkers and Clinical Outcomes in Dementia With Lewy Bodies NCT03888222 | Georgetown University | Phase 2 |
| Completed | Misfolded Proteins in the Skin of People With Parkinson's Disease and Other Parkinsonism NCT04518059 | University Hospitals Cleveland Medical Center | — |
| Unknown | Brain Network Activation in Patients With Movement Disorders NCT03269201 | Sheba Medical Center | — |
| Completed | A Double-Blind, Placebo-Controlled Safety and Efficacy Study of NA-831 NCT03538522 | Biomed Industries, Inc. | Phase 2 |
| Unknown | The China Longitudinal Aging Study of Cognitive Impairment NCT03672448 | Shanghai Mental Health Center | — |
| Enrolling By Invitation | North American Prodromal Synucleinopathy Consortium NCT03623672 | Washington University School of Medicine | — |
| Recruiting | Studies of Brain and Body Interaction NCT03672266 | Rutgers University | — |
| Completed | In-Home Care for Patients With PSP and Related Disorders NCT03552484 | Rush University Medical Center | N/A |
| Completed | Study To Evaluate the Efficacy, Safety and Tolerability of E2027 (Hereinafter Referred to as Irsenontrine) in NCT03467152 | Eisai Inc. | Phase 2 |
| Completed | Movement and Music Intervention for Individuals With Dementia NCT03121950 | Ohio State University | N/A |
| Terminated | Open-label Study of Nelotanserin in Lewy Body Dementia With Visual Hallucinations or REM Sleep Behavior Disord NCT02871427 | Axovant Sciences Ltd. | Phase 2 |
| Terminated | Long-Term Extension Study of Intepirdine (RVT-101) in Subjects With Dementia With Lewy Bodies: HEADWAY-DLB Ext NCT02928445 | Axovant Sciences Ltd. | Phase 2 / Phase 3 |
| Completed | Study Evaluating Intepirdine (RVT-101) on Gait and Balance in Subjects With Dementia NCT02910102 | Axovant Sciences Ltd. | Phase 2 |
| Completed | Study Evaluating Nelotanserin for Treatment of REM Sleep Behavior Disorder in Subjects With Dementia (DLB or P NCT02708186 | Axovant Sciences Ltd. | Phase 2 |
| Completed | Retinal Abnormalities as Biomarker of Disease Progression and Early Diagnosis of Parkinson Disease NCT02640339 | NYU Langone Health | — |
| Completed | Study Evaluating Intepirdine (RVT-101) in Subjects With Dementia With Lewy Bodies: The HEADWAY-DLB Study NCT02669433 | Axovant Sciences Ltd. | Phase 2 |
| Completed | Imaging Inflammation in Patients With Parkinson's Disease Dementia or Dementia With Lewy Bodies NCT02702102 | Columbia University | Phase 2 |
| Completed | Deep Brain Stimulation for Patients With Dementia With Lewy Bodies NCT02263937 | University College, London | N/A |
| Completed | Focused Ultrasound Thalamotomy for Tremor Relief in Atypical Parkinsonism NCT06204575 | Rambam Health Care Campus | — |
| Completed | Effects of Nucleus Basalis of Meynert Stimulation on Cognitive Disorders in Dementia With Lewy Bodies NCT01340001 | University Hospital, Rouen | N/A |
| Recruiting | Modifiable Variables in Parkinsonism (MVP) NCT02194816 | Bastyr University | — |
| Recruiting | Natural History Study of Synucleinopathies NCT01799915 | NYU Langone Health | — |
| Completed | The Swedish BioFINDER Study NCT01208675 | Skane University Hospital | — |
| Completed | A Trial of 18F-AV-133 and 18F-AV-45 Positron Emission Tomography (PET) NCT01503944 | Avid Radiopharmaceuticals | Phase 1 / Phase 2 |
| Recruiting | Cerebro Spinal Fluid Collection (CSF) NCT04844060 | University Hospital, Strasbourg, France | — |
| Completed | "Pilot Study of Armodafinil in Patients With Dementia With Lewy Bodies" NCT01023672 | Mayo Clinic | Phase 4 |
| Withdrawn | Treating Sleep/Wake Cycle Disturbances in Basal Ganglia Disorders With Ramelteon NCT00907595 | Massachusetts General Hospital | N/A |
| Completed | Imaging of Vesicular Acetylcholine and Dopamine Transporters in Dementia With Lewy Bodies NCT00917709 | University Hospital, Bordeaux | N/A |
| Enrolling By Invitation | Imaging of Brain Amyloid Plaques in the Aging Population NCT00950430 | Mayo Clinic | Phase 4 |
| Completed | Memantine Versus Placebo in Parkinson's Disease Dementia or Dementia With Lewy Bodies NCT00855686 | H. Lundbeck A/S | Phase 4 |
| Completed | Efficacy and Safety of Memantine for Parkinson's Disease Dementia (PDD) and Dementia With Lewy Bodies (DLB) NCT00630500 | Helse Stavanger HF | Phase 2 |
| Completed | Factors Associated With Mortality, Morbidity and Prognosis in Dementia Patients NCT05052450 | Gulhane Training and Research Hospital | — |
| No Longer Available | Expanded Access Program for CT1812 (Zervimesine) NCT06961760 | Cognition Therapeutics | — |