Trials / Completed
CompletedNCT01340001
Effects of Nucleus Basalis of Meynert Stimulation on Cognitive Disorders in Dementia With Lewy Bodies
Effects of Nucleus Basalis of Meynert Area Electrical Stimulation on Cognitive Behavioral Disorders in Dementia With Lewy Bodies : A Pilot Phase 1 Study
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 6 (actual)
- Sponsor
- University Hospital, Rouen · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
Deep brain stimulation has been developed as a substitute for the classical lesioning methods previously used in stereotactic and functional neurosurgery. Recent, anecdotal cases reports suggested that electrical stimulation of the cholinergic output of the Nucleus Basalis of Meynert (NBM) may improve cognitive performances, especially the memory tasks. The present study aims to assess the effect of bilateral electrical stimulation of the NBM on the mnesic performance \[assessed by the sum of the three free recalls of the Free and Cued Selective Recall Reminding Test (FCSRT)\] in patients diagnosed with probable, moderate, Dementia with Lewy Bodies.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Electrical stimulation of the nucleus basalis of Meynert | Differents parameters will be assessed. |
Timeline
- Start date
- 2012-10-24
- Primary completion
- 2017-12-22
- Completion
- 2017-12-22
- First posted
- 2011-04-21
- Last updated
- 2018-04-30
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT01340001. Inclusion in this directory is not an endorsement.