NCT05326750

Non-invasive Neurostimulation as a Tool for Diagnostics and Management for Neurodegenerative Diseases

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Kuopio University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Double blinded, sham-controlled, randomized trial on repeated transcranial alternating current brain stimulation (tACS) in neurodegenerative diseases. The investigators will evaluate whether a 4-times daily repeated stimulation with gamma tACS on the posterior parietal cortex can improve symptoms in patients with neurodegenerative diseases, including dementia with Lewy Bodies, Alzheimer's disease, idiopathic normal pressure hydrocephalus and Frontotemporal dementia.

Detailed description

Double blinded, sham-controlled, randomized trial on repeated transcranial alternating current brain stimulation (tACS) in neurodegenerative diseases. The investigators will evaluate whether a 4-times daily repeated stimulation with gamma tACS on the posterior parietal cortex can improve symptoms in patients with neurodegenerative diseases, including dementia with Lewy Bodies, Alzheimer's disease, idiopathic normal pressure hydrocephalus and Frontotemporal dementia.

Conditions

• Alzheimer Disease
• Frontotemporal Dementia
• Dementia With Lewy Bodies

Interventions

Type	Name	Description
DEVICE	Gamma tACS (40 Hz) over the superior parietal cortex	Single session of gamma tACS (40 Hz) over the superior parietal cortex

Timeline

• Start date: 2022-11-21
• Primary completion: 2032-07-01
• Completion: 2032-07-01
• First posted: 2022-04-14
• Last updated: 2025-09-03

Locations

1 site across 1 country: Finland