Clinical Trials Directory

Trials / Terminated

TerminatedNCT04831281

ATH-1017 Treatment in Subjects With Parkinson's Disease Dementia or Dementia With Lewy Bodies (SHAPE Trial)

A Randomized, Placebo-Controlled, Double-Blind Study of ATH-1017 Treatment in Subjects With Parkinson's Disease Dementia or Dementia With Lewy Bodies

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
28 (actual)
Sponsor
LeonaBio · Industry
Sex
All
Age
40 Years – 85 Years
Healthy volunteers
Not accepted

Summary

This study is designed to evaluate the safety and treatment effects of fosgonimeton (ATH-1017) in subjects with Parkinson's Disease Dementia or Dementia with Lewy Bodies, with a randomized treatment duration of 26 weeks.

Detailed description

The study is designed to evaluate the safety and treatment effects of ATH-1017 in subjects with Parkinson's Disease Dementia or Dementia with Lewy Bodies, with a randomized, double-blind, placebo-controlled, parallel-arm treatment duration of 26 weeks.

Conditions

Interventions

TypeNameDescription
DRUGATH-1017Daily subcutaneous injection of ATH-1017 in a pre-filled syringe
DRUGPlaceboDaily subcutaneous injection of Placebo in a pre-filled syringe

Timeline

Start date
2022-01-20
Primary completion
2023-04-19
Completion
2023-04-19
First posted
2021-04-05
Last updated
2025-03-04
Results posted
2025-03-04

Locations

10 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT04831281. Inclusion in this directory is not an endorsement.