| Not Yet Recruiting | Study of the Shockwave Medical SkyRunner Carotid Intravascular Lithotripsy (IVL) System for the Treatment of C NCT07512128 | Shockwave Medical, Inc. | N/A |
| Not Yet Recruiting | Study of the Shockwave Medical SkyRunner Carotid Intravascular Lithotripsy (IVL) System for the Treatment of C NCT07062471 | Shockwave Medical, Inc. | N/A |
| Not Yet Recruiting | Study to Image Inflammatory Activity of a Fluorescence Imaging Agent in Excised Human Artery Plaques NCT06957821 | Massachusetts General Hospital | EARLY_Phase 1 |
| Recruiting | Intervascular Post-Market Clinical Follow-Up (PMCF) Registry NCT07322913 | Intervascular | — |
| Recruiting | Oral Microbiome in Carotid Atherosclerosis NCT07296965 | Semmelweis University Heart and Vascular Center | — |
| Recruiting | Study on the Trans-Carotid Artery Occlusion Shunt System NCT06924593 | Shenzhen Wecan Medical Technology Co.,Ltd | N/A |
| Recruiting | Hemodynamic Monitoring Carotid Surgery NCT06926010 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | N/A |
| Recruiting | A Single-arm, Pivotal Study to Evaluate Acute Device and Technical Success of the CGuard Prime Carotid Stent S NCT06653387 | InspireMD | N/A |
| Terminated | ROADSTER 3 Extended Follow-up Sub-Study NCT06470815 | Silk Road Medical | — |
| Recruiting | Highest Efficacy of Dual Antiplatelet Therapy After Carotid Artery Stenting in High Bleeding Risk Patients NCT06276374 | Woo-Keun Seo | N/A |
| Recruiting | Study on the Trans-Carotid Artery Occlusion Shunt System Combined With Introducer Sets NCT06959628 | Shenzhen Wecan Medical Technology Co.,Ltd | N/A |
| Recruiting | The Role of Maintaining External Carotid Artery Flow in Graft Interposition After Carotid Endarterectomy NCT06528717 | Institute for Cardiovascular Diseases Dedinje | — |
| Completed | Study on the Trans-Carotid Artery Occlusion Shunt System Combined With Introducer Sets NCT06864299 | Shenzhen Wecan Medical Technology Co.,Ltd | N/A |
| Withdrawn | Immunomodulatory Effects of PCSK9 Inhibition NCT05720156 | Massachusetts General Hospital | — |
| Unknown | Feasibility of a Multifaceted Program to Reduce Cardiovascular Complications of Air Pollution NCT06261606 | Parham Sadeghipour | N/A |
| Completed | Direct Access Carotid Artery Stenting Using the Neuroguard IEP System (PERFORMANCE III) NCT05845710 | Contego Medical, Inc. | N/A |
| Completed | Ischemic Postconditioning in Carotid Surgery NCT06359756 | Institute for Cardiovascular Diseases Dedinje | N/A |
| Recruiting | Prediction of Cerebral Hyperperfusion Syndrome After Carotid Revascularization Using Deep Learning NCT05800821 | State Institution "Republican Scientific and Practical Center" Cardiology, Belarus | — |
| Unknown | The VANGAS-Trial. The Value of Neurofilament Light Chain and Glial Fibrillary Acid Protein in the Blood of Pat NCT06211725 | Heinrich-Heine University, Duesseldorf | — |
| Unknown | Timing Carotid Stent Clinical Study for the Treatment of Carotid Artery Stenosis（Timing Trial） NCT05574972 | Suzhou Zenith Vascular Scitech Co., Ltd. | N/A |
| Unknown | Platelet Function and Neurological Events NCT05572320 | Scientific Institute San Raffaele | — |
| Unknown | A Multicenter Study of Ultrafast Pulse Wave Velocity in Obese Chinese Han Adults NCT05455099 | First Hospital of China Medical University | — |
| Recruiting | Stress Reduction Using Video Googles on Patients Undergoing Vascular Surgery NCT06704230 | University Hospital Augsburg | N/A |
| Completed | Post-approval Study of Transcarotid Artery Revascularization in Standard Risk Patients With Significant Caroti NCT05365490 | Silk Road Medical | — |
| Active Not Recruiting | Radial Versus Femoral Access For Carotid Artery Stenting NCT05416853 | The First Affiliated Hospital of University of Science and Technology of China | N/A |
| Unknown | Digital Variance Angiography for Contrast Media Dose Reduction in Carotid Artery Stenting NCT04792255 | Kinepict Health Ltd. | N/A |
| Completed | "Carotid Web Incidence and Radiological Classification, Determination of Its Relationship With Ischemic Stroke NCT06058507 | Suleyman Demirel University | — |
| Unknown | SSPC Evaluation on Carotid Artery Stenosis After Endarterectomy NCT05296876 | Shanghai Pudong Hospital | — |
| Withdrawn | ACHIEVE GRX Registry NCT04513613 | Corindus Inc. | — |
| Terminated | A Lithium-Based Medication to Improve Neurological Outcomes After Surgical Carotid Reconstruction NCT05126238 | Negovsky Reanimatology Research Institute | Phase 3 |
| Completed | CArotid Robotic Procedure Evaluation NCT05093127 | Robocath | — |
| Completed | Early Detection of Vascular Dysfunction Using Biomarkers From Lagrangian Carotid Strain Imaging NCT04632485 | University of Wisconsin, Madison | — |
| Recruiting | Carotid Intraplaque Neovascularization Combined With Stress Echo NCT05416385 | Dr. Amer Johri | — |
| Recruiting | Assessing Neurocognition After Cerebrovascular Intervention NCT03344276 | University of California, San Diego | N/A |
| Completed | Ultrafast Ultrasound Imaging Assesment of Carotid Plaque Neovascularization NCT04470687 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Vitamin D Deficiency as Independent Predictor for Plaque Vulnerability NCT06473337 | Medical University of Vienna | — |
| Completed | Is Carotid-Vertebral Doppler Ultrasonography Necessary for Patients With Vertigo? NCT05196685 | Pamukkale University | — |
| Unknown | Relationship Between Morbimortality and Basal Activated Clotting Time (ACT) in Patients Undergoing Vascular Su NCT04703582 | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | — |
| Unknown | Frailty in Vascular Patients Undergoing Surgery NCT03668821 | Imperial College London | — |
| Unknown | The Carotid Artery Multi-modality Imaging Prognostic (CAMP) Study NCT04679727 | Azienda Ospedaliero, Universitaria Pisana | — |
| Recruiting | Endovascular Acute Stroke Intervention - Tandem OCclusion Trial NCT04261478 | Centre hospitalier de l'Université de Montréal (CHUM) | N/A |
| Unknown | The Changes in Carotid Plaque Neovascularization After Elovocumab Therapy NCT04423406 | Zibo Central Hospital | — |
| Active Not Recruiting | Protection Against Emboli During Carotid Artery Stenting Using the Neuroguard IEP System NCT04201132 | Contego Medical, Inc. | N/A |
| Unknown | TCAR Cerebral Protection And MicroNET-Covered Stent To Reduce Strokes NCT04547387 | John Paul II Hospital, Krakow | — |
| Active Not Recruiting | Thrombectomy In TANdem Occlusion NCT03978988 | Central Hospital, Nancy, France | N/A |
| Unknown | Carotid Stenosis Management During COVID-19 Era - Pilot Study NCT04947046 | Zealand University Hospital | — |
| Unknown | OPTIMAl Endovascular Exclusion of Consecutive Patient High-risk Carotid Plaque Using the MicroNet Covered Sten NCT04234854 | John Paul II Hospital, Krakow | — |
| Recruiting | Change of Hemodynamics and Cerebral Functions After Carotid Artery Revascularization NCT05539781 | Beijing Friendship Hospital | — |
| Recruiting | Biomarkers and Unstable Carotid Plaque NCT06887894 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Completed | The ENROUTE Transcarotid Neuroprotection System (ENROUTE Transcarotid NPS) DW-MRI Evaluation NCT03982420 | Silk Road Medical | — |
| Recruiting | The Management of Asymptomatic Carotid Stenosis NCT06882954 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Completed | Post-market, Prospective Evaluation of PHOTO-oxidized Bovine Pericardium in Vascular Surgery NCT03669042 | Artivion Inc. | N/A |
| Withdrawn | Carotid Artery Disease After Stroke (CADAS). NCT03721523 | University of Manchester | — |
| Completed | Assessment of Carotid Artery Stenosis and Lower Limb Peripheral Ischemia Prior to CABG NCT03516929 | Mr Ihab Ali | N/A |
| Unknown | Radiation-associated Carotid Artery Disease in Patients With Nasopharyngeal Carcinoma NCT03568032 | Fudan University | — |
| Completed | Embolic Signals Detection Study (Esds) in Candidates for Surgical Carotid Revascularisation NCT05134493 | Azienda Ospedaliero-Universitaria di Modena | — |
| Unknown | The Relationship Between Morbid Obesity and Carotid Artery Stenosis NCT03306771 | HaEmek Medical Center, Israel | — |
| Completed | Hemodynamics and Autonomic and Cognitive Performance After Carotid Revascularization Procedures NCT03493971 | Ospedale San Donato | N/A |
| Completed | Modified Method of Eversion Carotid Endarterectomy in Patients With Extensive Atherosclerotic Disease of Carot NCT04255316 | Pirogov Russian National Research Medical University | N/A |
| Unknown | Multicenter Normal Reference Study of Carotid Artery Ultrafast Pulse Wave Velocity (UFPWV) NCT03351127 | Shengjing Hospital | — |
| Completed | Investigation of Contact Based Method for Diagnosis of Cardiovascular Disease NCT03217214 | National Heart Centre Singapore | — |
| Completed | Assessment of Dapagliflozin Effect on Diabetic Endothelial Dysfunction of Brachial Artery NCT02919345 | University of Campinas, Brazil | Phase 4 |
| Recruiting | MicroNet-covered Stent System for Stroke Prevention in All Comer Carotid Revascularization NCT04271033 | John Paul II Hospital, Krakow | N/A |
| Completed | The ENROUTE Transcarotid Neuroprotection System (ENROUTE Transcarotid NPS) DW-MRI Study NCT03985774 | Silk Road Medical | — |
| Recruiting | The CREST-2 Registry NCT02240862 | University of Maryland, Baltimore | — |
| Completed | Effect of Regional Versus General Anesthesia on Thirty-day Outcomes Following Carotid Endarterectomy: a Matche NCT05706688 | University of Virginia | — |
| Completed | Body Cooling During Carotid Endarterectomy: No-profit, Open, Mono-centric, Feasibility Study NCT02629653 | S. Andrea Hospital | N/A |
| Completed | Safety and Performance Evaluation of WIRION™ EPD in Patients Undergoing Carotid Artery Stenting NCT01783639 | Gardia Medical | N/A |
| Recruiting | Multimodal Imaging Assessment of the Inflammatory Atheromatous Plaque NCT01608516 | University of Lausanne Hospitals | Phase 1 / Phase 2 |
| Completed | Outcome of LA Versus GA for Staged CEA Prior To CABG NCT04901000 | Thomas Aherne | — |
| Completed | GORE Flow Reversal System and GORE Embolic Filter Extension Study NCT01343667 | W.L.Gore & Associates | N/A |
| Unknown | Clinical and Laboratory Biomarkers in Patients With Atherothrombotic Stroke NCT02450721 | St. Petersburg State Pavlov Medical University | — |
| Unknown | Early Warning and Optimization Strategy in Carotid Endarterectomy NCT01210937 | Peking Union Medical College Hospital | Phase 4 |
| Completed | Specific Lp(a) Apheresis for Regression of Coronary and Carotid Atherosclerosis NCT02133807 | Russian Cardiology Research and Production Center | Phase 3 |
| Completed | Silk Road Medical First in Man Study - Neuroprotection During Carotid Stenting and Angioplasty NCT01264419 | Silk Road Medical | N/A |
| Completed | Carotid Plaque Characteristics by MRI in AIM-HIGH (Carotid MRI Substudy) NCT01178320 | University of Washington | — |
| Unknown | Pitavastatin on Carotid Intima-media Thickness NCT00711919 | Kyoto Prefectural University of Medicine | N/A |
| Unknown | Genetic- and Biological-Markers of Predisposition to Atherosclerosis: Leipzig-Heart Study NCT00497887 | University of Leipzig | — |
| Completed | Progression of Sub-Clinical Atherosclerosis NCT00241787 | Tufts Medical Center | — |
| Completed | Effect of Valsartan on Carotid Artery Disease NCT00208767 | Emory University | Phase 2 |
| Completed | Postapproval Trial On Carotid Stenting in Patients With High Risk Vs Standard Risk for Open Carotid Endarterec NCT02750644 | Joaquin de Haro, M.D. | — |
| Completed | Study of Carotid Occlusion and Neurocognition NCT00390481 | Columbia University | N/A |
| Completed | Inflammatory Genomics in Human Carotid Artery Disease NCT00070668 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Gene-by-Smoking Interactions and Risk of Atherosclerosis - Ancillary to ARIC NCT00064545 | University of North Carolina, Chapel Hill | — |
| Completed | Epidemiology of Carotid IMT Progression in MESA - Ancillary Study NCT00063440 | Tufts Medical Center | — |
| Completed | Boston Scientific Embolic Protection, Inc. (EPI): A Carotid Stenting Trial for High-Risk Surgical Patients (BE NCT00316108 | Boston Scientific Corporation | N/A |
| Completed | VA HDL Intervention Trial (VA-HIT) Ancillary Study Data Analysis NCT00035711 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Evaluate Carotid Artery Plaque Composition by Magnetic Resonance Imaging in People Receiving Cholesterol Medic NCT00715273 | University of Washington | Phase 4 |
| Completed | Risk of Coronary Heart Disease in Women With Polycystic Ovary Syndrome NCT00005459 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Prevalence & Progression of Subclinical Atherosclerosis NCT00006503 | Rush University Medical Center | — |
| Completed | Arterial Endothelial Function--An Epidemiologic Study NCT00005545 | University of Iowa | — |
| Completed | Diabetes, Lipoproteins and Accelerated Vascular Disease NCT00005479 | Columbia University | — |
| Completed | Epidemiology of Carotid Artery Atherosclerosis in Youth NCT00005397 | Patricia H Davis | — |
| Terminated | Vitamin E and C to Slow Progression of Common Carotid Artery Plaque Build-Up NCT00000600 | National Heart, Lung, and Blood Institute (NHLBI) | Phase 2 |
| Completed | Novel Hemostatic Cardiac Risk Factors in Framingham NCT00005356 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Early Atherosclerosis Change in Two Clinical Trials NCT00005696 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Postprandial Lipoproteins and Atherosclerosis NCT00005263 | Columbia University | — |
| Completed | Mechanisms Underlying Psychosocial Associations With Ischemic Heart Disease (Kuopio) NCT00005260 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Strong Heart Study NCT00005134 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Epidemiology of Carotid Disease in Elderly Adults NCT00005230 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Carotid Atherosclerosis Follow-up Study NCT00005189 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Epidemiology of Cardiovascular Risk Factors in Women (Healthy Women Study) NCT00005160 | University of Pittsburgh | — |
| Completed | Cholesterol-Lowering Atherosclerosis Study (CLAS) NCT00000599 | National Heart, Lung, and Blood Institute (NHLBI) | Phase 3 |