Trials / Unknown
UnknownNCT04423406
The Changes in Carotid Plaque Neovascularization After Elovocumab Therapy
The Changes in Carotid Plaque Neovascularization After Long-term Elovocumab Injection Therapy: A Follow-Up Study by Contrast Enhanced Ultrasonography
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 150 (estimated)
- Sponsor
- Zibo Central Hospital · Other Government
- Sex
- All
- Age
- 18 Years – 85 Years
- Healthy volunteers
- —
Summary
150 selected patients will be recruited, who have at least one atherosclerotic plaque in the carotid artery that is thicker than 2.0 mm and which is determined to be uniformly or predominantly echolucent by standard ultrasonography. For each of the plaques, standard ultrasonography will be used to evaluate lesion echogenicity, while contrast-enhanced ultrasonography (CEUS) will be used to perform the visual and quantitative analysis of neovascularization. Each technique will be applied at baseline (at the time of study enrollment) and following 0.5、1 year of Elococumab Injection treatment. During the study, these patients will be treated with Elococumab Injection (1ml:140mg),ih, every two weeks.
Conditions
Timeline
- Start date
- 2020-08-01
- Primary completion
- 2021-12-31
- Completion
- 2022-02-27
- First posted
- 2020-06-09
- Last updated
- 2021-04-21
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT04423406. Inclusion in this directory is not an endorsement.