NCT04901000

Outcome of LA Versus GA for Staged CEA Prior To CABG

Outcome of Local Versus General Anesthetic for Staged Carotid Endarterectomy Prior To CABG, Cohort Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 44 (actual)
• Sponsor: Thomas Aherne · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

A retrospective analysis of all patients that underwent carotid endarterectomy (CEA) for stenotic disease - diagnosed at pre-operative investigation - prior to CABG as staged operation within 6- months. The rate of postoperative stroke and complications was compared between CEA performed under Local anaesthetic (LA) to those performed under General anaesthetic (GA).

Detailed description

The primary outcome was the rate of postoperative stroke in patients that had staged CEA prior to CABG. This was defined as CEA within a period of 4 weeks prior to CABG. We retrospectively looked at those patients that fulfilled the inclusion criteria and had CEA performed either under LA (Group A) or under GA (Group B). We measured the 30 days' postoperative stroke rate as the main outcome. We also looked at the rate of intraoperative stroke. Additionally, we assessed the rate for developing nerve injuries and/or hematoma postoperatively. Finally, we examined the risk for developing postoperative stroke in patients with bilateral significant carotid artery disease that underwent surgery in one side.

Conditions

• Carotid Artery Diseases
• Coronary Artery Disease
• Stroke

Interventions

Type	Name	Description
PROCEDURE	Carotid endarterectomy	Carotid endarterectomy prior to CABG operations either under Local Anaesthetic or under General Anaesthetic.

Timeline

• Start date: 2011-10-01
• Primary completion: 2018-09-30
• Completion: 2018-09-30
• First posted: 2021-05-25
• Last updated: 2021-05-25