Clinical Trials Directory

Trials / Conditions / Tourette Syndrome

Tourette Syndrome

160 registered clinical trials studyying Tourette Syndrome24 currently recruiting.

StatusTrialSponsorPhase
Not Yet RecruitingCharacterising Sleep Disorders in Children With Tourette Syndrome
NCT07450079
Steffi Baker
RecruitingWhere Wild Things Grow: Nature- and Activity-based Group Interventions for Neurodivergent Children and Youth
NCT07203469
Sorlandet Hospital HFN/A
Not Yet RecruitingSCI-110 in the Treatment of Tourette Syndrome
NCT05126888
Neurothera Labs Inc.Phase 2
RecruitingCognitive-psychophysiological Treatment for Tics in Young People With Tourette's Syndrome With or Without Biof
NCT06873841
Université du Québec a MontréalN/A
RecruitingTrajectories of Change in Tourette Syndrome
NCT06679790
University of MinnesotaN/A
RecruitingCBIT+TMS R33 Phase
NCT06678737
University of MinnesotaPhase 2
RecruitingMultimodal Electrophysiological Study of Cortico-subcortical Biomarkers of Tics in Tourette Syndrome
NCT06909656
University Hospital, BordeauxN/A
RecruitingEffect of RNS in Treatment-refractory Tourette's Syndrome
NCT06785532
Xuanwu Hospital, BeijingN/A
RecruitingSensorimotor and Psychosocial Trajectories in Adolescents With Tic Disorder
NCT06576726
Vanderbilt University Medical Center
RecruitingMultitarget Stereotactic Electrophysiological Recording and Stimulation for Tourette Syndrome
NCT06889480
Beijing Tiantan HospitalN/A
RecruitingEffectiveness of Symptom Management Application on Parental Care Ability of Children With Tourette Syndrome
NCT06613126
National Taipei University of Nursing and Health SciencesN/A
RecruitingSertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents With NeurodevelopMental Disorde
NCT06081348
Holland Bloorview Kids Rehabilitation HospitalPhase 2
Active Not RecruitingEfficacy and Safety of Gemlapodect (NOE-105) in Adults and Adolescents With Tourette Syndrome
NCT06315751
Noema Pharma AGPhase 2
RecruitingA Multicenter Pediatric Deep Brain Stimulation Registry
NCT06585618
Boston Children's Hospital
RecruitingRemote Delivery of a Mindfulness-based Intervention for Tics
NCT06408662
Johns Hopkins UniversityN/A
RecruitingEpidemiology of Assertiveness and Emotion Management Disorders in People With Tourette's Syndrome
NCT06136572
University Hospital, Clermont-FerrandN/A
RecruitingMultimodal Profiling of Response to Pediatric Comprehensive Behavioral Intervention for Tics
NCT06194305
University of MinnesotaPhase 2
RecruitingWashed Microbiota Transplantation for Tourette's Syndrome
NCT03764748
The Second Hospital of Nanjing Medical UniversityPhase 1
RecruitingClinical Characteristics and Temporal Properties of Individual Tics in Persistent Tic Disorder
NCT06385535
University of UtahN/A
RecruitingStrengthening Tourette Treatment OPtions Using TMS to Improve CBIT, a Double-blind, Randomized, Controlled Stu
NCT05705999
West Virginia UniversityN/A
RecruitingInternet-based Behavior Therapy for Adults With Tourette Syndrome
NCT06271083
Karolinska InstitutetN/A
Active Not RecruitingA Study to Evaluate Long-term Safety of Ecopipam Tablets in Children, Adolescents and Adults With Tourette's D
NCT06021522
Emalex Biosciences Inc.Phase 3
UnknownEvaluation of an Online Comprehensive Behavioral Intervention for Tics (CBIT) Therapist Training Program
NCT05547854
University of UtahN/A
WithdrawnD-cycloserine Augmented Treatment for Youth With Tic Disorders
NCT04357951
Johns Hopkins UniversityEARLY_Phase 1
CompletedTourette Discrimination (TD) Stigma Scale
NCT05696769
Wake Forest University Health Sciences
WithdrawnNew Stereotactic Frame System for Neurosurgery
NCT04283812
Mayo ClinicN/A
CompletedTheta Burst Stimulation to Improve Inhibitory Motor Physiology in Tourette Syndrome
NCT05628805
Children's Hospital Medical Center, CincinnatiN/A
CompletedDeep Brain Stimulation in Tourette Syndrome
NCT06388291
University College, LondonN/A
Active Not RecruitingTourette Deep Brain Stimulation (DBS) Target Detection & Suppression
NCT05371041
University of FloridaN/A
CompletedInvestigating Distress Tolerance in Adults With Tourette Syndrome
NCT05047705
Johns Hopkins UniversityN/A
TerminatedAtomoxetine in Patients With Tourette's Syndrome
NCT04354103
Poitiers University HospitalPhase 2
CompletedInvestigations of the Pathophysiology of Gilles de la Tourette Syndrome. Part 1: Simultaneous PET and 3T MRI
NCT05232955
Max Planck Institute for Human Cognitive and Brain Sciences
CompletedEpidiolex in Obsessive Compulsive Disorder and Related Disorders
NCT04978428
University of ChicagoPhase 2
CompletedMedian Nerve Stimulation for Tourette Syndrome and Chronic Tic Disorder
NCT05269953
Nottingham University Hospitals NHS TrustN/A
UnknownEvaluate the Efficacy, Safety and Tolerability of TSUPPORT for Adults With Tourette Syndrome
NCT05183594
Tasly Pharmaceuticals, Inc.N/A
CompletedA Study to Explore the Effect of Sepranolone in Tourette Syndrome
NCT05434546
Asarina PharmaPhase 2
CompletedInvestigations of the Pathophysiology of Gilles de la Tourette Syndrome. Part 2: 7T MRI
NCT05233306
Max Planck Institute for Human Cognitive and Brain Sciences
WithdrawnSafety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for Tourette Syndrome
NCT05158439
The Foundation for Orthopaedics and Regenerative MedicinePhase 1
CompletedCombined CBIT and rTMS to Improve Tourette's Syndrome
NCT04795908
University of FloridaN/A
CompletedOpen-label MNS for Tourette Syndrome
NCT05016765
Washington University School of MedicineN/A
RecruitingLongitudinal Impact of Stressors in Adults With Tourette Syndrome
NCT04851678
Vanderbilt University Medical Center
Enrolling By InvitationNeural Correlates of Sensory Phenomena in Tourette Syndrome
NCT03914664
Vanderbilt University Medical Center
CompletedMedian Nerve Stimulation Pilot
NCT04731714
Washington University School of MedicineN/A
UnknownInternet-based Cognitive Behavioral Therapy for Chronic Tic Disorder and Tourette's Disorder: a Feasibility Tr
NCT04908969
Karolinska InstitutetN/A
CompletedInfluence of Stress and Psychiatric Symptoms on Children With Tourette Syndrome
NCT04449003
Vanderbilt University Medical Center
CompletedA Handwriting Intervention Program for Children With Tic Disorders
NCT04246112
University of Alabama at BirminghamN/A
RecruitingObservational Database on Deep Brain Stimulation in Tourette Syndrome
NCT04449068
Assistance Publique - Hôpitaux de Paris
CompletedTranscranial Magnetic Stimulation to Augment Behavior Therapy for Tics
NCT04578912
University of MinnesotaN/A
CompletedExtinction Learning in Adults With Tourette Syndrome
NCT04498364
Johns Hopkins UniversityN/A
CompletedThe Effect of Medical Cannabis on Tics, Premonitory Urge and Psychiatric Comorbidity in Adults With Tourette S
NCT05115318
Tel-Aviv Sourasky Medical Center
CompletedSensory Symptoms in Tourette Syndrome and Obsessive-Compulsive Disorder
NCT04335175
Vanderbilt University Medical Center
WithdrawnMulti-site Transcranial Magnetic Stimulation Therapy of the Supplementary Motor Area in Children With Tourette
NCT03642951
Children's Mercy Hospital Kansas CityN/A
CompletedEcopipam Tablets to Study Tourette's Syndrome in Children and Adolescents
NCT04007991
Emalex Biosciences Inc.Phase 2
CompletedResponse Inhibition in Tourette Syndrome
NCT03628703
Children's Hospital Medical Center, CincinnatiN/A
RecruitingSensory Symptoms in Tourette Syndrome
NCT03851484
Vanderbilt University Medical Center
UnknownDeep Brain Stimulation in Forel's H Field in Tourette's Syndrome
NCT04342754
University of Sao Paulo General HospitalN/A
UnknownOutcomes Mandate National Integration With Cannabis as Medicine
NCT03944447
OMNI Medical Services, LLCPhase 2
UnknownExploration of Glutamatergic System With PET Radiotracer in Gilles de la Tourette Patients: Pilot Study (Gluta
NCT03681795
University Hospital, ToulouseN/A
CompletedPimavanserin Treatment in TS
NCT04794413
Joseph JankovicEARLY_Phase 1
CompletedOnline Mindfulness-based Tic Reduction (Phase Two)
NCT03771235
Bowdoin CollegeN/A
TerminatedRollover Study for Continuing NBI-98854 Administration in Pediatric Subjects With Tourette Syndrome
NCT03732534
Neurocrine BiosciencesPhase 2
CompletedStudy of ABX-1431 in Adult Patients With Tourette Syndrome or Chronic Motor Tic Disorder
NCT03625453
Abide TherapeuticsPhase 2
UnknownA Study to Examine the Efficacy of a Therapeutic THX-110 for Tourette Syndrome
NCT03651726
Neurothera Labs Inc.Phase 2
CompletedAn Exploratory Study of Continuous Theta Burst Stimulation (cTBS) Based on fMRI in the Treatment of Tic Disord
NCT04128397
Second Affiliated Hospital, School of Medicine, Zhejiang UniversityN/A
CompletedA Study to Test if TEV-50717 is Effective in Relieving Tics Associated With Tourette Syndrome (TS)
NCT03571256
Teva Branded Pharmaceutical Products R&D, Inc.Phase 3
TerminatedEvaluation of Safety and Tolerability of Long-term TEV-50717 (Deutetrabenazine) for Treatment of Tourette Synd
NCT03567291
Teva Branded Pharmaceutical Products R&D, Inc.Phase 3
CompletedOnline Remote Behavioural Intervention for Tics (ORBIT)
NCT03483493
Nottinghamshire Healthcare NHS TrustN/A
CompletedAripiprazole Oral Solution in the Treatment of Children and Adolescents With Tourette's Syndrome
NCT03487783
Otsuka Beijing Research InstitutePhase 3
CompletedImpulse Control in Gilles de la Tourette Syndrome
NCT04197804
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
UnknowntDCS in Tourette (TIC-TDCS)
NCT03401996
University of CalgaryN/A
TerminatedSafety and Efficacy of NBI-98854 in Pediatric Subjects With Tourette Syndrome
NCT03530293
Neurocrine BiosciencesPhase 2
TerminatedGilles de la Tourette Syndrome (TS) and Seasonality
NCT04076852
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
CompletedCANNAbinoids in the Treatment of TICS (CANNA-TICS)
NCT03087201
Hannover Medical SchoolPhase 3
CompletedOnline Mindfulness-based Tic Reduction
NCT03525626
Bowdoin CollegeN/A
CompletedOpen-Label Safety and Tolerability Study of NBI-98854 for the Treatment of Pediatric Subjects With Tourette Sy
NCT03444038
Neurocrine BiosciencesPhase 2
CompletedAlternatives for Reducing Tics in Tourette Syndrome (TS): A Study of TEV-50717 (Deutetrabenazine) for the Trea
NCT03452943
Teva Branded Pharmaceutical Products R&D, Inc.Phase 2 / Phase 3
CompletedRole of Frontal Cortex in the Pathophysiology of Gilles de la Tourette Syndrome (GTS)
NCT03604510
University Hospital, BordeauxN/A
TerminatedSafety and Efficacy of Cannabis in Tourette Syndrome
NCT03247244
University Health Network, TorontoPhase 2
CompletedSafety, Tolerability, and Efficacy of NBI-98854 for the Treatment of Pediatric Subjects With Tourette Syndrome
NCT03325010
Neurocrine BiosciencesPhase 2
UnknownThe Role of Probiotics PS128 in Movement Disorders
NCT03259971
National Taiwan University HospitalN/A
CompletedEffects of Ondansetron in Obsessive-compulsive and Tic Disorders
NCT03239210
NYU Langone HealthPhase 4
CompletedBehavioral Therapy for Tourette Syndrome
NCT03019731
Johns Hopkins UniversityN/A
CompletedA Study to Evaluate the Effects of ABX-1431 on Patients With Tourette Syndrome
NCT03058562
Abide TherapeuticsPhase 1
CompletedEfficacy of a Therapeutic Combination of Dronabinol and PEA for Tourette Syndrome
NCT03066193
Yale UniversityPhase 2
UnknownThe Safety and Efficacy of Long-term Treatment of PINS Stimulator System for Tourette Syndrome
NCT02253498
Beijing Pins Medical Co., LtdEARLY_Phase 1
CompletedImpulsivity in Tourette Syndrome : Behavioral and Neuroimaging Study
NCT02960698
Institut National de la Santé Et de la Recherche Médicale, FranceN/A
CompletedTrial to Demonstrate the Efficacy and Safety of Internet-delivered Behavioral Treatment for Adults With Tic Di
NCT02605902
Hannover Medical SchoolN/A
CompletedIncorporating teleCBIT Into a Hospital-Based Tic Program
NCT04007913
San Jose State UniversityN/A
CompletedModified Comprehensive Behavioral Intervention for Tics (M_CBIT)
NCT02900144
Massachusetts General HospitalN/A
CompletedSafety and Tolerability Study of NBI-98854 for the Treatment of Subjects With Tourette Syndrome
NCT02879578
Neurocrine BiosciencesPhase 2
CompletedComputerized Working Memory Training in Children With ADHD and Comorbid Tourette Syndrome
NCT02732496
Massachusetts General HospitalN/A
CompletedEvaluation of a Cognitive Psychophysiological Treatment for Tourette Syndrome and Tic Disorders
NCT03225430
Centre de Recherche de l'Institut Universitaire en santé Mentale de MontréalN/A
CompletedApathy in Tourette Syndrome and Changes in Quality of Life
NCT02765178
University of Florida
CompletedSafety and Efficacy Study of NBI-98854 in Children and Adolescents With Tourette Syndrome
NCT02679079
Neurocrine BiosciencesPhase 2
CompletedSafety and Efficacy Study of NBI-98854 in Adults With Tourette Syndrome
NCT02581865
Neurocrine BiosciencesPhase 2
CompletedSensory Processing in Tourette Syndrome
NCT02512406
University of Florida
CompletedTranscranial Magnetic Stimulation for Children With Tourette's Syndrome
NCT02356003
University of CalgaryN/A
UnknownGroup Intervention for Children With Chronic Tics Syndrome or Tourette Syndrome: CBIT vs Psycho-Educational In
NCT02407951
Tel-Aviv Sourasky Medical CenterN/A
WithdrawnA Trial Evaluating the Efficacy, Safety, and Pharmacokinetics of SNC-102 in Subjects With Tourette Syndrome
NCT02217007
Synchroneuron Inc.Phase 2
UnknownThe Effect and Safety of Plum-blossom Needle for Tourette Syndrome
NCT02403258
Guang'anmen Hospital of China Academy of Chinese Medical SciencesN/A
CompletedBehavioral Therapy for Children and Adolescents With Tourette Syndrome
NCT03621059
Taipei Medical UniversityN/A
CompletedSafety, Pharmacokinetics, and Pharmacodynamics of NBI-98854 in Children and Adolescents With Tourette Syndrome
NCT02256475
Neurocrine BiosciencesPhase 1
CompletedBrain Stimulation in Movement Disorders
NCT02216474
Birmingham and Solihull Mental Health NHS Foundation TrustN/A
CompletedA Pilot Study Of SD-809 (Deutetrabenazine) In Moderate To Severe Tourette Syndrome (TS)
NCT02674321
Auspex Pharmaceuticals, Inc.Phase 1
UnknownParent Behavioral Training for Disruptive Behaviors in Tourette Syndrome
NCT02882490
Hospital Clinic of BarcelonaN/A
TerminatedFAAH Inhibitor Trial for Adults With Tourette Syndrome
NCT02134080
Yale UniversityPhase 1
CompletedThalamic Deep Brain Stimulation for Tourette Syndrome
NCT03958617
University of ColognePhase 2 / Phase 3
CompletedActivity in Tourette Syndrome
NCT02153463
Children's Hospital of Eastern OntarioN/A
CompletedTourette Syndrome Deep Brain Stimulation
NCT02056873
University of FloridaN/A
CompletedProof of Concept Study of an Oral Orthotic to Reduce Tic Severity in Chronic Tic Disorder and Tourette Syndrom
NCT02067819
Weill Medical College of Cornell UniversityN/A
TerminatedThalamic Deep Brain Stimulation for the Treatment of Refractory Tourette Syndrome
NCT01817517
Johns Hopkins UniversityN/A
UnknownPilot Study for Use of Dysport in Treatment of Vocal Tics in Patients With Tourette's Syndrome
NCT02187679
Detroit Clinical Research CenterN/A
UnknownThe Pathophysiology of Tourette Syndrome: a Multimodal Study
NCT02497807
Second Affiliated Hospital, School of Medicine, Zhejiang University
CompletedSafety, Tolerability, Pharmacokinetic, and Efficacy Study of AZD5213 in Adolescents With Tourette's Disorder
NCT01904773
AstraZenecaPhase 2
CompletedVoIP Delivered Behavior Therapy for Tourette Syndrome
NCT02247206
University of Wisconsin, MilwaukeePhase 2
CompletedOpen-Trial of EPI-743 for Adults With Tourette Syndrome
NCT01719523
Yale UniversityPhase 1
CompletedNeurofeedback for Tourette Syndrome
NCT01702077
Yale UniversityN/A
CompletedGuanfacine in Children With Tic Disorders
NCT01547000
Yale UniversityPhase 4
CompletedSubthalamic Stimulation in Tourette's Syndrome
NCT02619084
Fondazione I.R.C.C.S. Istituto Neurologico Carlo BestaPhase 2
CompletedDeveloping Cognitive Training for Tourette Syndrome
NCT01440023
University of Wisconsin, MilwaukeePhase 1
CompletedA Trial of Bilateral Deep Brain Stimulation to the Globus Pallidus Internum in Tourette Syndrome
NCT01647269
University College, LondonPhase 2
CompletedRepetitive Transcranial Magnetic Stimulation to Reduce Tics
NCT01258790
Children's Hospital Medical Center, CincinnatiN/A
CompletedAssessment of Children With Tic Onset in the Past 6 Months
NCT01177774
Washington University School of Medicine
Active Not RecruitingOutcomes of Cognitive Behavioral Therapy (CBT) Interventions Provided by Unlicensed Professionals
NCT01075672
Massachusetts General HospitalN/A
CompletedMRI Study of Tic Remission in Tourette Syndrome
NCT01405859
University of Utah
CompletedDeveloping New Treatments for Tourette Syndrome: Therapeutic Trials With Modulators of Glutamatergic Neurotran
NCT01018056
Johns Hopkins UniversityPhase 4
CompletedBrain Stimulation for the Treatment of Tourette Syndrome
NCT01329198
University of FloridaN/A
TerminatedInvestigation of Neurofeedback With Real-Time fMRI in Healthy Volunteers and Patients With Hyperkinetic Moveme
NCT00885040
National Institute of Neurological Disorders and Stroke (NINDS)
CompletedRole of the Sensory Experience in Generating Motor Tics in Tourette Syndrome
NCT00755339
National Institute of Neurological Disorders and Stroke (NINDS)
TerminatedPilot Study of the Modified Atkins Diet for Tourette Syndrome
NCT00952601
Johns Hopkins UniversityPhase 1
TerminatedOpen-label Extension Study of Pramipexole in the Treatment of Children and Adolescents With Tourette Syndrome
NCT00681863
Boehringer IngelheimPhase 3
CompletedPramipexole Pilot Phase II Study in Children and Adolescents With Tourette Disorder According to DSM-IV Criter
NCT00558467
Boehringer IngelheimPhase 2
CompletedPhase III Study of 5LGr to Treat Tic Disorder
NCT01501695
Tasly Pharmaceuticals, Inc.Phase 3
CompletedTranscranial Magnetic Stimulation (TMS) for Individuals With Tourette's Syndrome
NCT00529308
Yale UniversityPhase 2
CompletedComparison of Keppra and Clonidine in the Treatment of Tics
NCT00370838
Harvey S. SingerPhase 4
UnknownSedation During Microelectrode Recordings Before Deep Brain Stimulation for Movement Disorders.
NCT00355927
Hadassah Medical OrganizationN/A
CompletedDopaminergic Effects on Cortical Function in Tourette's (Levodopa Protocol)
NCT00634556
Washington University School of MedicinePhase 1
CompletedEffectiveness of Behavior Therapy and Psychosocial Therapy for the Treatment of Tourette Syndrome and Chronic
NCT00231985
Massachusetts General HospitalPhase 2
CompletedBrain Activity Associated With Tics in Patients With Tourette Syndrome
NCT00141869
National Institute of Neurological Disorders and Stroke (NINDS)
CompletedThalamic Deep Brain Stimulation for Tourette Syndrome
NCT00311909
University Hospitals Cleveland Medical CenterPhase 2
CompletedCognitive Behavior Therapy and Habit Reversal Training for the Treatment of Chronic Tic Disorders in Children
NCT00218777
Tourette Association of AmericaPhase 2 / Phase 3
CompletedAn Open-label Study to Determine the Efficacy and Safety of Topiramate in the Treatment of Tourette Syndrome.
NCT00206336
Baylor College of MedicinePhase 3
CompletedA Randomized, Placebo-controlled, Tourette Syndrome Study.
NCT00206323
Baylor College of MedicinePhase 3
CompletedTiming of Voluntary Movement in Patients With Tourette Syndrome and Chronic Tic Disorder
NCT00081419
National Institute of Neurological Disorders and Stroke (NINDS)
CompletedBrain Dynamics Involved in Generating Tics and Controlling Voluntary Movement
NCT00056420
National Institute of Neurological Disorders and Stroke (NINDS)
CompletedStudy of GABA-A Receptors in the Generation of Tics in Patients With Tourette's Syndrome
NCT00034398
National Institute of Neurological Disorders and Stroke (NINDS)
CompletedStudy of Tics in Patients With Tourette's Syndrome and Chronic Motor Tic Disorder
NCT00033995
National Institute of Neurological Disorders and Stroke (NINDS)
CompletedMagnetic Resonance Spectroscopy to Evaluate Tourette s Syndrome
NCT00030953
National Institute of Neurological Disorders and Stroke (NINDS)
CompletedAnger Control Training for Youth With Tourette Syndrome
NCT00486551
Yale UniversityN/A
CompletedMethylphenidate for Treating Children With ADHD and Tourette Syndrome
NCT00441649
Stony Brook UniversityN/A
CompletedEvaluation and Follow-up of Individuals With Obsessive-Compulsive Disorder and Related Conditions
NCT00004550
National Institute of Mental Health (NIMH)
CompletedI-123 Brain Studies of Serotonin Metabolism in Psychiatric Patients and Normal Volunteers
NCT00001771
National Institute of Mental Health (NIMH)
CompletedPhase II Double Blind Placebo Controlled Trial of Risperidone in Tourette Syndrome
NCT00004393
National Center for Research Resources (NCRR)Phase 2
CompletedRandomized Study of Pergolide in Children With Tourette Syndrome
NCT00004433
Children's Hospital Medical Center, CincinnatiN/A
CompletedPhase III Randomized, Double-Blind, Placebo-Controlled Study of Guanfacine for Tourette Syndrome and Attention
NCT00004376
National Center for Research Resources (NCRR)Phase 3
CompletedPhase II Pilot Controlled Study of Short Vs Longer Term Pimozide (Orap) Therapy in Tourette Syndrome
NCT00004652
National Center for Research Resources (NCRR)Phase 2
TerminatedCentral Mechanisms in Speech Motor Control Studied With H215O PET
NCT00001308
National Institute on Deafness and Other Communication Disorders (NIDCD)
CompletedDevelopmental Phenomenology of Obsessive Compulsive Disorder and Tourette Syndrome in Children and Adolescents
NCT00004324
National Center for Research Resources (NCRR)
CompletedStudy of the Neurobiology of Tourette Syndrome and Related Disorders
NCT00004325
National Center for Research Resources (NCRR)
UnknownNational Gilles De La Tourette Study Group
NCT00169351
Groupe Hospitalier Pitie-Salpetriere