Clinical Trials Directory

Trials / Terminated

TerminatedNCT03530293

Safety and Efficacy of NBI-98854 in Pediatric Subjects With Tourette Syndrome

A Phase 2, Double-Blind, Placebo-Controlled, Randomized Withdrawal Study to Evaluate the Safety and Efficacy of NBI-98854 in Pediatric Subjects With Tourette Syndrome

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
81 (actual)
Sponsor
Neurocrine Biosciences · Industry
Sex
All
Age
6 Years – 17 Years
Healthy volunteers
Not accepted

Summary

This is a Phase 2, double-blind, placebo-controlled, randomized withdrawal study to evaluate the safety and maintenance of efficacy of an optimized once-daily (qd) dose of NBI-98854 in pediatric subjects with TS.

Conditions

Interventions

TypeNameDescription
DRUGValbenazinevesicular monoamine transporter 2 (VMAT2) inhibitor
DRUGPlacebo oral capsulenon-active dosage form

Timeline

Start date
2018-04-17
Primary completion
2019-07-16
Completion
2019-07-16
First posted
2018-05-21
Last updated
2022-05-17
Results posted
2022-05-17

Locations

49 sites across 2 countries: United States, Puerto Rico

Regulatory

Source: ClinicalTrials.gov record NCT03530293. Inclusion in this directory is not an endorsement.