NCT04498364

Extinction Learning in Adults With Tourette Syndrome

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Johns Hopkins University · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Accepted

Summary

Aversive sensory phenomena such as premonitory urges play a central role in the behavioral treatment model of tics. Extinction learning and extinction recall are learning processes implicated within this model, but are still understudied for individuals with Tourette syndrome (TS). This study examines extinction learning and extinction recall in adults with TS using an experimental task. This study will also explore the relationship between extinction processes (i.e., extinction learning and extinction recall) and treatment outcomes with behavior therapy. Findings from this investigation will be used to update the behavioral treatment model, which serves as the basis for evidence-based behavioral interventions.

Conditions

• Tourette Syndrome
• Habit Reversal Training
• Tic Disorders
• Tics
• Comprehensive Behavioral Intervention for Tics

Interventions

Type	Name	Description
BEHAVIORAL	Habit Reversal Training	Habit Reversal Training (HRT) is a multi-component evidence-based treatment for tics.

Timeline

• Start date: 2020-09-18
• Primary completion: 2023-09-22
• Completion: 2023-10-17
• First posted: 2020-08-04
• Last updated: 2023-10-23

Locations

1 site across 1 country: United States