| Not Yet Recruiting | Digital MEDIcal TWIN for the Prediction of Arrhythmic Sudden Cardiac Death After a Myocardial Infarction NCT07527494 | University Hospital, Bordeaux | N/A |
| Enrolling By Invitation | Functional Substrate-Only Guided VT Ablation NCT06464315 | VA Office of Research and Development | N/A |
| Not Yet Recruiting | Skeletal Muscle Multi-omics Analysis and Risk Tailoring in Sudden Cardiac Death NCT07476456 | China National Center for Cardiovascular Diseases | — |
| Not Yet Recruiting | Dilated Cardiomyopathy - Unknown Therapeutic Risk Reduction by Contempary Medication and Implantable Cardiover NCT07415642 | University Medical Center Groningen | N/A |
| Recruiting | Left Bundle Branch Pacing in Patients With Hypertrophic Cardiomyopathy After Myectomy NCT07372196 | Meshalkin Research Institute of Pathology of Circulation | N/A |
| Recruiting | Comparative Effectiveness of Carvedilol Versus Metoprolol Succinate in Heart Failure Patients With an Implanta NCT06964464 | University of Rochester | Phase 4 |
| Recruiting | National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in B NCT06546137 | Hospital do Coracao | — |
| Recruiting | Mechanisms And Prognosis of Stroke-Heart Syndrome NCT06954103 | Chensheng Pan | — |
| Recruiting | S-ICD Implantation: US Based Pilot Study NCT06771700 | Universitätsklinikum Köln | N/A |
| Recruiting | Tampere Coronary Artery Disease and Sudden Cardiac Arrest Study NCT06804499 | Tampere Heart Hospital | — |
| Recruiting | Validation of Sudden Cardiac Arrest Risk Factors in Patients With CAD NCT07444931 | Tampere Heart Hospital | — |
| Recruiting | Sudden Cardiac Arrest Related to Sport in Young and Value of the Genetic Assessment: a French Prospective Regi NCT06642168 | Rennes University Hospital | — |
| Recruiting | Speed-up the Diagnosis and Evaluation of anoMalous Coronary ARTery From the Aorta NCT06705751 | IRCCS Policlinico S. Donato | N/A |
| Completed | Early Double Sequential Defibrillation in Out-of-hospital Cardiac Arrest NCT06447805 | Karolinska Institutet | N/A |
| Not Yet Recruiting | MAgnetic Resonance Imaging-guided implanTation of Cardioverter DEFibrillators NCT06269692 | Central Hospital, Nancy, France | N/A |
| Recruiting | Multicenter Evaluation of Patients Using LATITUDE Monitoring System NCT06311149 | University Hospital of Ferrara | — |
| Recruiting | Prevention Of Sudden Cardiac Death After Myocardial Infarction by Defibrillator Implantation NCT05665608 | Charite University, Berlin, Germany | N/A |
| Unknown | S-ICD Electrode Registry NCT05713708 | Universitätsklinikum Köln | — |
| Recruiting | Post-market Surveillance of Micorport CRM Cardiac Implantable Electronic Devices NCT05694572 | MicroPort CRM | — |
| Unknown | Low QRS Voltages in Young Healthy Individuals and Athletes NCT05799833 | Imperial College London | — |
| Recruiting | AI-powered ECG Analysis Using Willem™ Software in High-risk Cardiac Patients (WILLEM) NCT05890716 | Idoven 1903 S.L. | — |
| Recruiting | Pre-warning Risk Scoring System for Sudden Cardiac Death NCT06440083 | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | — |
| Unknown | REgiStry in Chinese yoUng pEople With Sudden Cardiac Death NCT05713240 | China National Center for Cardiovascular Diseases | — |
| Recruiting | Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or Venetoclax NCT05724121 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Recruiting | Characterization of Patients With Cardiomyopathy to Identify Critical Patients Candidates for Cardiac Transpla NCT06813443 | IRCCS Azienda Ospedaliero-Universitaria di Bologna | — |
| Unknown | Genome-Wide Association Study With the Aim of Implantable Cardioverter Defibrillator Implantation Genophenotyp NCT05582252 | Selcuk University | — |
| Unknown | Electroanatomic Interactions Between Transcatheter Pulmonary Valve Prostheses and Anatomic Isthmuses in Repair NCT05236153 | Boston Children's Hospital | N/A |
| Unknown | Acute Changes in Plasma Glucose and Cardiovascular Disease in Diabetes NCT05500352 | Steno Diabetes Center Copenhagen | N/A |
| Recruiting | The International SubcutaneouS Implantable Cardioverter Defibrillator Registry (iSuSI) NCT05390047 | University of Luebeck | — |
| Recruiting | Early Evaluation of Exosome Multiomics and Clinical Prognosis in Patients With Sudden Death NCT06856993 | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | — |
| Completed | New Patient-specific Functional Assessment of the Anomalous Aortic Origin of Coronary Arteries. NCT05159791 | IRCCS Policlinico S. Donato | N/A |
| Unknown | REal World Assessment for Patients Implanted With Implantable CardioverTer DefibrIllatOr Using Bluetooth Techn NCT05175937 | Federico II University | — |
| Unknown | Cardiac Sympathetic Denervation for Prevention of Ventricular Tachyarrhythmias NCT01013714 | University of California, Los Angeles | Phase 3 |
| Unknown | Preventive VT Substrate Ablation in Ischemic Heart Disease NCT04675073 | Centro Medico Teknon | Phase 3 |
| Completed | Exploration of Arrhythmia Burden in Cardiac Amyloidosis Using Implantable Loop Recorders NCT04856267 | Marianna Fontana | — |
| Unknown | South Asian Arrhythmogenic Cardiomyopathy Registry NCT04895540 | Sheri Kashmir Institute of Medical Sciences | — |
| Unknown | Mobile Electrocardiogram Monitoring for Detecting Arrhythmias in Children NCT05140343 | Centro Medico Teknon | N/A |
| Completed | Cardiac Rehab Retrospective Review (CR3) NCT04675957 | Medical University of Graz | — |
| Withdrawn | Personalised Risk scOre For Implantation of Defibrillators in Patients With Reduced LVEF≤35% and a Low Risk fo NCT04540354 | Helios Health Institute GmbH | N/A |
| Withdrawn | Personalised Risk scOre For Implantation of Defibrillators in Patients With Preserved LVEF>35% and a High Risk NCT04540289 | Helios Health Institute GmbH | N/A |
| Completed | Cardiopulmonary Resuscitation Performance of Professional Rescuers With a New Defibrillation Algorithm NCT04691089 | French Defence Health Service | — |
| Unknown | Epidemiological Study of Out-of-hospital Cardiac Arrest in Guangzhou NCT06448156 | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | — |
| Completed | Optimization of VNS in Epileptic Patients to Induce Cardioprotection NCT04387435 | University of California, Los Angeles | N/A |
| Completed | Micophenolate Mofetil Versus Azathioprine in Myocarditis NCT05237323 | I.M. Sechenov First Moscow State Medical University | Phase 3 |
| Unknown | CMR Based Prediction of Ventricular Tachycardia Events in Healed Myocardial Infarction (DEVELOP-VT) NCT04599439 | Centro Medico Teknon | — |
| Unknown | Better Mechanistic Understanding of and Risk Stratification for Ventricular Tachyarrhythmias Through ECGI NCT04548804 | Maastricht University Medical Center | N/A |
| Unknown | Acute Cardiovascular Events Triggered by COVID-19-Related Stress NCT04368637 | Jordan Collaborating Cardiology Group | — |
| Unknown | Experience From the Italian S-ICD Registry NCT04373876 | Luigi Sacco University Hospital | — |
| Unknown | Electromechanical Profiling of the Long-QT Syndrome (LQTS) NCT04074122 | Maastricht University Medical Center | — |
| Recruiting | Myocardialbridge Bypass Graft Surgery Efficacy Verification NCT06857838 | Xi'an International Medical Center Hospital | N/A |
| Completed | SCREENING FOR THE IMPLANTATION OF A SUBCUTANEOUS IMPLANTABLE AUTOMATIC DEFIBRILLATOR NCT04101253 | Centre Hospitalier de PAU | N/A |
| Unknown | Electrophysiological Phenotyping Of Patients at Risk of Ventricular Arrhythmia and Sudden Cardiac Death NCT03910725 | Imperial College London | — |
| Active Not Recruiting | Arrhythmia in Hemodialysis Patients NCT04036695 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | N/A |
| Completed | Smoking and Ventricular Repolarization NCT03916341 | University of California, Los Angeles | N/A |
| Unknown | Prospective Clinical Registry of Subcutaneous Implantable Cardioverter Defibrillator (S-ICD) (S-ICD Korea Regi NCT04127643 | Yonsei University | — |
| Unknown | Noninvasive Electrocardiographic Imaging for Individuals at Risk for Apparently Idiopathic Ventricular Fibrill NCT03963271 | Maastricht University Medical Center | — |
| Completed | Canadian Sudden Cardiac Arrest Network NCT03642587 | Unity Health Toronto | — |
| Recruiting | European Prospective Registry on Anomalous Aortic Origin of the Coronary Arteries NCT06089902 | University of Padova | — |
| Unknown | ARrhythmias in MYocarditis NCT03801681 | Medical University of Warsaw | — |
| Unknown | Subcutaneous ICD Therapy Combined With VT Ablation for the Secondary Prevention of Sudden Cardiac Death NCT03622307 | Sheba Medical Center | N/A |
| Completed | Sudden Cardiac Death in Systemic Right Ventricle NCT03833843 | European Georges Pompidou Hospital | — |
| Unknown | A Prospective,Multiple Center,Cohort Study of Prediction Model on Sudden Cardiac Death and Devices Development NCT03485079 | Jingfeng Wang | — |
| Completed | TroponinT After Subcutaneous Cardioverter-Defibrillator Implantation NCT03526302 | Deutsches Herzzentrum Muenchen | — |
| Completed | CIQTP Prolongation : Role and Mechanism in Sudden Cardiac Death NCT03387072 | Nantes University Hospital | — |
| Recruiting | Mayo AVC Registry and Biobank NCT03049254 | Mayo Clinic | — |
| Terminated | Benefits of ICD for the Primary Prevention in Patients With Valvular Cardiomyopathy NCT03590730 | Keimyung University Dongsan Medical Center | — |
| Completed | Domperidone and Risk of Serious Cardiac Events in Postpartum Women NCT04024865 | Canadian Network for Observational Drug Effect Studies, CNODES | — |
| Completed | Heart Failure and Sudden Cardiac Death Japan Registry NCT03185832 | Boston Scientific Corporation | — |
| Unknown | Prediction of Sudden Cardiac Death in Dilated Cardiomyopathy NCT03224156 | University Hospital Heidelberg | — |
| Completed | Exploring Mechanisms and Morphology of QT Interval Prolongation NCT03291145 | Herlev and Gentofte Hospital | N/A |
| Completed | The Role of Electrophysiology Testing in Survivors of Unexplained Cardiac Arrest NCT03079414 | Western University, Canada | — |
| Completed | Early Initiation of Extracorporeal Life Support in Refractory OHCA NCT03101787 | Maastricht University Medical Center | N/A |
| Terminated | Stress ECG Test for the Evaluation of the Risk of Sudden Cardiac Death in a Paediatric Cohort With WPW Pattern NCT03207373 | Christian Balmer | N/A |
| Completed | Heart Failure Optimization Study NCT03016754 | Zoll Medical Corporation | — |
| Completed | LifeVest Safety and Efficacy in Real Life Settings in France NCT03319160 | Zoll Medical Corporation | — |
| Active Not Recruiting | PRecIsion Medicine in CardiomyopathY NCT04036799 | The Hospital for Sick Children | — |
| Recruiting | Implantable Cardioverter Defibrillator Versus Optimal Medical Therapy In Patients With Variant Angina Manifest NCT02845531 | Kee-joon Choi | Phase 4 |
| Completed | Integrated Informatics-imaging Approaches to Cardiovascular Disease. NCT06718465 | University of Edinburgh | — |
| Completed | Assessment of Primary Prevention Patients Receiving An ICD - Systematic Evaluation of ATP NCT02923726 | Boston Scientific Corporation | N/A |
| Completed | Educational Videos to Address Racial Disparities in Implantable Cardioverter Defibrillator Therapy NCT02819973 | Duke University | N/A |
| Completed | Prognostic Value of Ventricular Fibrillation Spectral Analysis in Sudden Cardiac Death NCT03248557 | Hospital San Carlos, Madrid | — |
| Unknown | Registry of Malignant Arrhythmias and Sudden Cardiac Death - Influence of Diagnostics and Interventions NCT02982473 | Universitätsmedizin Mannheim | — |
| Unknown | European Sleep Apnea and Sudden CArdiac Death ProjEct NCT02506166 | University Hospital Olomouc | N/A |
| Completed | To Determine Optimal Time for Delivering Electrical Shocks to Cardiac Arrest Patients NCT01665755 | Singapore General Hospital | N/A |
| Terminated | Wearable Cardioverter Defibrillator in Hemodialysis Patients (WED-HED) Study NCT02481206 | Zoll Medical Corporation | N/A |
| Completed | A Pilot Trial of Patient Decision Aids for Implantable Cardioverter-Defibrillators (ICDs) NCT02026102 | University of Colorado, Denver | N/A |
| Withdrawn | Is Left Stellate Ganglionectomy Beneficial to Patients With Life Threatening Ventricular Arrhythmias NCT02113722 | Cindy Hall | N/A |
| Recruiting | Programmed Ventricular Stimulation to Risk Stratify for Early Cardioverter-Defibrillator (ICD) Implantation to NCT03588286 | Western Sydney Local Health District | N/A |
| Completed | Ethnicity and Onset of Cardiovascular Disease: A CALIBER Study NCT02176174 | University College, London | — |
| Terminated | Study of Paced QRS Duration as a Marker of Sudden Cardiac Death NCT01948206 | Pocono Medical Center | — |
| Unknown | Utilising Lifemap to Investigate Malignant Arrhythmia Therapy NCT02058771 | University Hospitals, Leicester | — |
| Unknown | The Effect of Chest Compression and Ventilation Coordination During Cardiopulmonary Resuscitation. NCT02056509 | National Taiwan University Hospital | — |
| Completed | Heart Rate Response to Regadenoson and Sudden Cardiac Death NCT01842035 | University of Alabama at Birmingham | N/A |
| Completed | DF4 Master Study (Safety and Efficacy Study) NCT01790841 | Biotronik SE & Co. KG | — |
| Completed | Vitamin D and Cardiac Autonomic Tone in Hemodialysis NCT01774812 | University of Calgary | Phase 2 |
| Unknown | S-ICD French Cohort Study (HONEST) NCT05302115 | Paris Sudden Death Expertise Center | — |
| Completed | Feasibility Testing of Decision Support for Patients Who Are Candidates for an Implantable Defibrillator NCT01876173 | McMaster University | N/A |
| Completed | Ability of Home Monitoring® to Detect and Manage the Inappropriate Diagnoses in Implantable Cardioverter Defib NCT01594112 | Biotronik SE & Co. KG | — |
| Completed | Inflammation, Cardiac Sympathetic Innervation, and Arrhythmic Sudden Death NCT01919983 | Johns Hopkins University | — |
| Unknown | Sudden Cardiac Death Stratification in Myotonic Dystrophy Type 1 Patients NCT03784586 | University of Campania Luigi Vanvitelli | — |
| Unknown | Sudden Cardiac Death - Screening Of Risk Factors NCT01845909 | University of Coimbra | — |
| Completed | DF4 Connector System Post-Approval Study NCT01638897 | Medtronic | — |
| Completed | Comparison of a MAGNET Protocol Versus "off-on" Protocol for Patients With Implantable Cardioverter Defibrilla NCT01599065 | Midwest Heart Foundation | — |
| Completed | The Circadian Rhythm of Potassium and Cystatin C NCT01318746 | University of Erlangen-Nürnberg Medical School | — |
| Completed | Hemodynamic Effects of Standard Cardiopulmonary Resuscitation (CPR), Active Compression Decompression CPR With NCT01325870 | Advanced Circulatory Systems | N/A |
| Terminated | LifeVest Post-CABG Registry NCT01448005 | Zoll Medical Corporation | — |
| Recruiting | Registry of Device Implantation NCT03360227 | Klinik für Kardiologie, Pneumologie und Angiologie | — |
| Recruiting | French National Registry of Patients With Tetralogy of Fallot and Implantable Cardioverter Defibrillator NCT03837574 | Paris Sudden Death Expertise Center | — |
| Completed | Next Generation INCEPTA Implantable Cardioverter Defibrillator (ICD) and Cardiac Resynchronization Therapy (CR NCT01227785 | Guidant Corporation | — |
| Completed | Development of Algorithms to Predict Hemodynamic Instability NCT01262508 | Klinik für Kardiologie, Pneumologie und Angiologie | — |
| Completed | Effects of Stearidonic Acid-Containing Foods on Eicosapentaenoic Acid Levels in Red Blood Cells and Omega-3 In NCT01749202 | Solae, LLC | N/A |
| Unknown | Risk Stratification in End Stage Renal Disease (ESRD) - ISAR Study NCT01152892 | Technical University of Munich | — |
| Completed | Implantable Cardioverter Defibrillators - Improving Risk Stratification NCT01944514 | University Hospitals, Leicester | — |
| Completed | An Arrhythmia Risk Stratification and Genetic Trial NCT01209494 | University Medical Center Goettingen | — |
| Completed | Effect of Ranolazine on Arrhythmias and Microvolt T- Wave Alternans (MVTWA) Patients With LV Dysfunction NCT00998218 | Aspirus Heart and Vascular Institute-Research and Education | Phase 3 |
| Completed | Time and Dose Evaluation of Stearidonic Acid (SDA) to Eicosapentaenoic Acid (EPA) in Red Blood Cells NCT01038440 | Solae, LLC | N/A |
| Completed | SJ4 Post Approval Study in Implantable Cardioverter-Defibrillator and Cardiac Resynchronization Therapy Defibr NCT00940888 | Abbott Medical Devices | — |
| Completed | Beer, Marathon, Genetics, Inflammation and the Cardiovascular System: Be-MaGIC-Trial NCT00933218 | Technical University of Munich | N/A |
| Completed | Comparison of 50% Tilt and Tuned Waveforms in Single-Coil Active Can Configuration NCT00874445 | Abbott Medical Devices | — |
| Completed | Pre-arrival Instructions Effect on Bystander Cardiopulmonary Resuscitation (CPR). NCT02007499 | Medical College of Wisconsin | — |
| Unknown | Occurrence, Trends, Management and Outcomes of Patients Hospitalized With Myocarditis NCT04827706 | Medical University of Warsaw | — |
| Completed | Hemodynamic Efficiency of an Hemodialysis Treatment With High Permeability in Post-resuscitation Shock NCT00780299 | Assistance Publique - Hôpitaux de Paris | Phase 3 |
| Completed | Marathon, Genetics, Inflammation and the Cardiovascular System: MAGIC-Trial NCT00845286 | Technical University of Munich | N/A |
| Completed | Thrombus and Inflammation Study in Sudden Cardiac DEath NCT00748111 | Assistance Publique - Hôpitaux de Paris | N/A |
| Terminated | Implantable Cardioverter Defibrillator (ICD) Support Groups and Veterans NCT00846417 | Emory University | — |
| Unknown | Evolution of Management Strategies of Heart Failure Patients With Implantable Defibrillators NCT00873899 | Regione Lombardia | — |
| Terminated | Longitudinal Surveillance Registry NCT00636272 | Boston Scientific Corporation | — |
| Completed | SAFEty of Two Strategies of ICD Management at Implantation NCT00661037 | Boston Scientific Corporation | — |
| Completed | Survival of Patients With Primary Prophylactic ICD Indication NCT00619593 | Biotronik SE & Co. KG | Phase 4 |
| Completed | 'Effect of CRT on Defibrillation Threshold Estimates' Study NCT00626093 | Abbott Medical Devices | Phase 4 |
| Completed | Predictive Risk Stratification Through T Variability in ICD Patients Without Pacing Indications NCT00560768 | LivaNova | Phase 4 |
| Terminated | Standard Drug Therapy vs. Implanted Defibrillator for Primary Prevention of Sudden Cardiac Death NCT00524862 | Unity Health Toronto | N/A |
| Completed | Intravenous n-3 Fatty Acids and Ventricular Tachycardia in Patients With Implantable Cardioverter Defibrillato NCT00534300 | Aalborg University Hospital | Phase 1 / Phase 2 |
| Unknown | Effects of Endurance Training on Patients With Reduced Left Ventricular Ejection Fraction (LVEF) and Cardiac R NCT00472238 | Charite University, Berlin, Germany | N/A |
| Completed | Exercise and Cardiac Measures in Dialysis Patients NCT00944775 | Aristotle University Of Thessaloniki | N/A |
| Active Not Recruiting | PRE-DETERMINE Cohort Study NCT01114269 | Brigham and Women's Hospital | — |
| Terminated | DEfibrillators To REduce Risk by MagnetIc ResoNance Imaging Evaluation NCT00487279 | Abbott Medical Devices | N/A |
| Completed | T-Wave Alternans in Dialysis Patients NCT00621426 | Northwestern University | — |
| Terminated | Treatment of Ventricular Tachyarrhythmias Refractory To Shock With Beta Blockers: The SHOCK and BLOCK Trial NCT00401882 | David Haines, MD | Phase 2 |
| Completed | POWER (Pulse Width Optimized Waveform Evaluation Trial) NCT00311181 | Abbott Medical Devices | Phase 4 |
| Completed | REASSURE AV Registry NCT01074034 | Boston Scientific Corporation | N/A |
| Completed | Ovatio DR and VR Implantable Cardioverter Defibrillators Post-approval Study NCT00586378 | ELA Medical, Inc. | Phase 3 |
| Completed | Study of the Implantable Cardioverter Defibrillator (ICD) Intracardiac Electrograms NCT00916435 | Johns Hopkins University | — |
| Unknown | Prediction of Mortality After CIED Implantation (PM-CIED) NCT05396313 | Shanghai Zhongshan Hospital | — |
| Terminated | CORE: Study to Evaluate the Conducted AF-Response-Algorithm in Patients Suffering From Heart Failure and Atria NCT00170313 | Medtronic Cardiac Rhythm and Heart Failure | Phase 4 |
| Recruiting | Imaging Techniques for Identifying Factors of Sudden Cardiac Death Risk NCT00181233 | Johns Hopkins University | — |
| Unknown | Prospective Study to Identify Patients at Risk of Dangerous Ventricular Arrhythmias NCT00562757 | Harbinger Medical, Inc. | — |
| Completed | DAVID II (Dual Chamber and VVI Implantable Defibrillator (DAVID) Trial II) NCT00187187 | Abbott Medical Devices | N/A |
| Unknown | Risk Indicators in Patients With Ventricular Fibrillation During Acute Myocardial Infarction NCT00175942 | Heidelberg University | — |
| Completed | RAMYD Study - Evaluation of Arrhythmic Risk in Myotonic Dystrophy NCT00127582 | Catholic University of the Sacred Heart | N/A |
| Completed | Long Term Integrity Follow-up Evaluation NCT00848835 | Guidant Corporation | — |
| Completed | Genetic Risk Assessment of Defibrillator Events NCT02045043 | University of Iowa | — |
| Unknown | Finnish Genetic Study for Arrhythmic Events NCT02075866 | University of Oulu | — |
| Unknown | The Role of Alcohol Consumption in the Aetiology of Different Cardiovascular Disease Phenotypes: a CALIBER Stu NCT01864031 | University College, London | — |
| Completed | Arrhythmias in Myotonic Muscular Dystrophy NCT00622453 | Indiana University School of Medicine | — |
| Unknown | Selection of Shock Energy in Out-Of-Hospital Cardiac Arrest NCT00472147 | Charite University, Berlin, Germany | N/A |