Trials / Unknown
UnknownNCT04074122
Electromechanical Profiling of the Long-QT Syndrome (LQTS)
Electromechanical Profiling of Arrhythmogenic Substrates and Triggers in the Long-QT Syndrome
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 150 (estimated)
- Sponsor
- Maastricht University Medical Center · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
High-resolution, non-invasive electromechanical mapping in genotyped long-QT syndrome patients and healthy controls at baseline and during smart provocation.
Detailed description
Using simultaneous ECG-imaging, speckle-tracking analysis and tissue-phase mapping with MRI we will assess electromechanical dispersion at rest. Regional electromechanical elasticity will be investigated during adenosine and epinephrine, isoprenaline infusions and is postulated to increase sudden cardiac death risk prediction in the individual patient.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | Adenosine and epinephrine, isoprenaline provocation | High-resolution electromechanical mapping at baseline and after provocative measures. |
Timeline
- Start date
- 2020-01-01
- Primary completion
- 2022-01-01
- Completion
- 2022-01-01
- First posted
- 2019-08-29
- Last updated
- 2019-08-29
Source: ClinicalTrials.gov record NCT04074122. Inclusion in this directory is not an endorsement.