NCT06857838

Myocardialbridge Bypass Graft Surgery Efficacy Verification

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 500 (estimated)
• Sponsor: Xi'an International Medical Center Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Myocardial Bridge Bypass Graft surgery is introduced to relieve the unmedical symptoms of patients with long-segment or deep myocardial bridge, clinical outcomes will be collected to verify the effectiveness of the surgery.

Conditions

• Myocardial Bridge of Coronary Artery
• Myocardial Bridge
• Myocardial Bridging
• Myocardial Infarction
• Myocardial Ischemia
• Pectoris, Stable Angina
• Sudden Cardiac Death
• Bypass Graft Stenosis
• Bypass Graft Occlusion
• Bypass Graft Thrombosis

Interventions

Type	Name	Description
PROCEDURE	MBBG	The patients with deep(depth\>2mm) and long-segement(length\>25mm) of myocardialbridge receiving myocardialbridge bypass graft surgery(MBBG)，fulfilling the following criteria: 1.presenting with pectoris angina that cannot be effectively relieved by maximum guideline-directed drug therapy; 2. No atherosclerotic plaque or merely mild atherosclerotic stenosis is detected at the proximal or entry of the myocardialbridge confirmed by coronory artery angiography.
PROCEDURE	MB CABG	The patients with deep(depth\>2mm) and long-segement(length\>25mm) of myocardialbridge receiving myocardialbridge bypass graft surgery(MBBG)，fulfilling the following criteria: 1.presenting with pectoris angina that cannot be effectively relieved by maximum guideline-directed drug therapy; 2. The moderate-to-severe atherosclerotic stenosis is detected at the proximal or entry of the myocardialbridge confirmed by coronory artery angiography.
PROCEDURE	MB unroof	The patients with superficial type(depth\<2mm) and short-segement(length\<25mm) of myocardial bridge will be allocated to receive myocardialbridge "unroof" surgery，when fulfilling the following criteria: 1.presenting with pectoris angina that cannot be effectively relieved by maximum guideline-directed drug therapy; 2. The MB was superficial and short confirmed by coronory artery CT angiography.

Timeline

• Start date: 2020-01-01
• Primary completion: 2030-12-31
• Completion: 2040-12-31
• First posted: 2025-03-04
• Last updated: 2025-03-04

Locations

1 site across 1 country: China