| Not Yet Recruiting | Under-Represented Communities Diagnosed With SCD or MCI Through Tele-Cog NCT06542458 | Ohio State University | — |
| Not Yet Recruiting | Chinese Classics Recitation Training in Subjective Cognitive Decline NCT07463391 | China Medical University Hospital | N/A |
| Recruiting | Prediction of Cognitive Test Performance Using AI-Based Analysis of Narrative Speech NCT07511270 | Chang Gung Memorial Hospital | N/A |
| Recruiting | Internet-based Mind-Body Training for Brain Health NCT07019402 | Ohio State University | N/A |
| Recruiting | Exergame-assisted Simultaneous Motor-cognitive Training for Middle-aged Old Adults in China NCT07085663 | The Hong Kong Polytechnic University | N/A |
| Recruiting | Attentional Mechanisms in SCD NCT06002477 | Vanderbilt University Medical Center | EARLY_Phase 1 |
| Not Yet Recruiting | Β-OHB Supplementation and Brain Health in Older Adults NCT06588946 | McMaster University | Phase 2 |
| Not Yet Recruiting | Effects of Individualized Theta-tACS on a Working Memory Training at SCD NCT06501755 | University Hospital Tuebingen | N/A |
| Active Not Recruiting | Gut-brain Health Effects of PREbiotics in Older Adults With Suspected COgnitive DEcline NCT06433037 | Wageningen University | N/A |
| Recruiting | REducing the Risk of COgnitive DEcline ad Dementia in Patients With Subjective Cognitive Decline Through an Im NCT06429215 | I.R.C.C.S. Fondazione Santa Lucia | N/A |
| Recruiting | Developing a Peer Support Intervention for Depression in SCD NCT06358404 | Massachusetts General Hospital | N/A |
| Recruiting | The Effects of Social Isolation and Social Interaction on the Risk of Dementia Progression and Brain Function NCT06335836 | The First Affiliated Hospital with Nanjing Medical University | — |
| Completed | Cognitive Intervention With Go and Chess in Early and Subjective Cognitive Decline NCT06281652 | University of Milano Bicocca | N/A |
| Recruiting | Thinking About Memory: How Confident Are You in Your Memory, and Does it Change With Age? NCT06539403 | King's College London | — |
| Recruiting | HOme-based Brain Monitoring With a GARment-EEG to Study Cognitive Decline in the Aging Population NCT06993207 | Bitbrain | — |
| Recruiting | dTMS for Subjective Cognitive Decline NCT06095063 | Rotman Research Institute at Baycrest | N/A |
| Completed | Efficacy of Tinkering Activities in Individuals With Subjective Cognitive Decline NCT06110858 | National Taiwan University Hospital | N/A |
| Completed | Effects of Mediterranean Diet on Subjective Cognitive Decline NCT06287489 | Chih-Ping Chung | N/A |
| Active Not Recruiting | The Lifestyle Exercise and Diet Trial (LEAD) 2.0 NCT06078748 | University of Waterloo | N/A |
| Unknown | Davos Alzheimer's Collaborative Healthcare System Preparedness to Increase Cognitive Assessment Rates for Olde NCT06191952 | Ludwig-Maximilians - University of Munich | N/A |
| Recruiting | German Validation Study of the Subjective Cognitive Decline Questionnaire (SCD-Q) NCT06711952 | Ludwig-Maximilians - University of Munich | N/A |
| Recruiting | Impact of Intensive Treatment of SBP on Brain Perfusion, Amyloid, and Tau (IPAT Study) NCT05331144 | Rong Zhang | Phase 2 |
| Completed | Senior Driving Simulation Training for Subjective Cognitive Decline and Mild Cognitive Impairment NCT05380284 | Taipei Medical University | N/A |
| Unknown | Technical R&D and Demonstration of Intelligent Medical Care in Alzheimer's Disease's Management NCT05641480 | Shaanxi Hospital of Traditional Chinese Medicine | N/A |
| Completed | Clinical Applicability of pCASL as a Substitute for FDG-PET in MCI and SCD Patients NCT05756270 | University of Milano Bicocca | — |
| Completed | Cholinergic Mechanisms of Attention in Aging NCT04756232 | Vanderbilt University Medical Center | EARLY_Phase 1 |
| Unknown | Effects of the Combining Physical Exercise and Cognitive Training for the Community-based Elderly NCT05225181 | Chang Gung Memorial Hospital | N/A |
| Completed | Brain Health Together: Development and Pilot Test NCT06914947 | University of California, San Francisco | — |
| Completed | DEMA-Pro Intervention for Seniors With Subjective Cognitive Decline and Living at Home NCT04796415 | Indiana University | N/A |
| Completed | Clinical and Biological Effects of Citrus-phytochemicals in Subjective Cognitive Decline. NCT04744922 | IRCCS Centro San Giovanni di Dio Fatebenefratelli | N/A |
| Unknown | Early Diagnosis of SCD Based on Radiogenomics NCT04696315 | XuanwuH 2 | — |
| Recruiting | Establish Diagnostic and Prognostic Models for Preclinical AD Patients Based on Multimodal MRI, Behavioral, Ge NCT06561906 | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | — |
| Withdrawn | Subjects With Subjective Cognitive Decline: 18F-Florbetaben Positron Emission Tomography Study NCT03057938 | Fundacion Clinic per a la Recerca Biomédica | Phase 2 |
| Completed | Effects of Online Training Aimed at Increasing Participation in Everyday Life During a Pandemic (SCD Online). NCT04439500 | Baycrest | N/A |
| Unknown | Effects of Cognitive Strategy Training on Daily Function in People With Subjective Cognitive Decline NCT04330404 | National Cheng Kung University | N/A |
| Unknown | Modulation of Attention in Event Related Potential (ERPs) as a Marker of Early Cognitive Decline by Ginkgo Bil NCT04121728 | Jean-François Démonet | N/A |
| Completed | Neuropsychological Indicators of SCD Progression NCT04880252 | Centre Hospitalier Universitaire, Amiens | — |
| Completed | Cognitive Training and Brain Stimulation in Prodromal Alzheimer's Disease NCT04265378 | University Medicine Greifswald | N/A |
| Completed | Neurofeedback Intervention for Preclinical Alzheimer's Disease NCT04300933 | XuanwuH 2 | N/A |
| Completed | Non-pharmacological Intervention for Preclinical Alzheimer's Disease NCT04279418 | XuanwuH 2 | N/A |
| Completed | Efficacy of a Multicomponent Cognitive Intervention in Adults With Subjective Cognitive Decline and Mild Cogni NCT04023032 | National Taiwan University Hospital | N/A |
| Completed | BarcelonaBeta Dementia Prevention Research Clinic: a Study on Risk Factors Disclosure NCT03847038 | Barcelonabeta Brain Research Center, Pasqual Maragall Foundation | N/A |
| Terminated | Lifestyle, Exercise and Diet: The LEAD Study NCT03056508 | Rotman Research Institute at Baycrest | N/A |
| Unknown | The Efficacy and Mechanism of Acupuncture Treatment in Patients With Subjective Cognitive Decline NCT03444896 | Beijing Hospital of Traditional Chinese Medicine | N/A |
| Recruiting | Longitudinal Study for the Characterization of the Phases of Subjective Perception of Cognitive Decline and Mi NCT03851523 | Barcelonabeta Brain Research Center, Pasqual Maragall Foundation | — |
| Completed | Preventing Cognitive and Functional Decline Among Seniors at Risk NCT03495037 | Baycrest | N/A |
| Active Not Recruiting | Impact of a Cognitive Intervention Enriched With Leisure Activities in Persons With Subjective Cognitive Decli NCT03271190 | Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal | N/A |
| Completed | tDCS-enhanced Working Memory Training in Subjective Cognitive Decline NCT03236454 | University Hospital Tuebingen | N/A |
| Active Not Recruiting | The Brain Health Champion Study NCT03772977 | Brigham and Women's Hospital | N/A |
| Completed | Prediction of Cognitive Decline by Neuroimaging Techniques and the Application in Diagnosis and Treatment of P NCT03370744 | XuanwuH 2 | — |
| Completed | Risk Reduction for Alzheimer's Disease NCT02913664 | University of Texas Southwestern Medical Center | Phase 2 / Phase 3 |
| Completed | Neurotrack Virtual Cognitive Health Study NCT02969460 | Evidation Health | N/A |
| Recruiting | China Diabetes Cognitive Dysfunction Early Diagnosis and Intervention Study (China-DECODE Study) NCT06650969 | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | — |
| Completed | Polyamine-enriched Diet in Healthy Older Adults With Subjective Cognitive Decline NCT02755246 | Charite University, Berlin, Germany | Phase 2 |