NCT06542458

Under-Represented Communities Diagnosed With SCD or MCI Through Tele-Cog

A Cohort Study of Older Adults From Under-resourced/Under-represented Communities Diagnosed With Subjective Cognitive Decline (SCD) or Mild Cognitive Disorder (MCI) Through Standard of Care Tele-Cog Visits (Tele-Cog)

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 1,000 (estimated)
• Sponsor: Ohio State University · Academic / Other
• Sex: All
• Age: 50 Years
• Healthy volunteers: Not accepted

Summary

Overall, this study's primary aim is to establish a prospective, longitudinal, observational cohort study of older adults at risk for dementia from under-resourced/underrepresented communities. More specifically, older adults diagnosed with subjective cognitive decline (SCD) or Mild Cognitive Impairment (MCI) during clinical care offered via the Tele-Cog clinic would be recruited for more comprehensive data collection to characterize the clinical presentation and course of illness over multiple timepoints spread out longitudinally.

Detailed description

Clinical data obtained as part of standard of care will be collected from the medical record (including clinical diagnosis, cognitive and other neuropsychological test scores, lab results, neuroimaging data, etc.) and additional data (neuropsychological test batteries and clinical questionnaires if not already obtained) would be obtained at research study visits. Participants will be asked to participate in annual research visits for up to 5 years.

Conditions

• Mild Cognitive Impairment
• Subjective Cognitive Decline

Interventions

Type	Name	Description
BEHAVIORAL	Assessments	Participants will undergo a standard battery of neuropsychological measures, behavioral questionnaire, and functional assessment to monitor cognition and function over time. Clinical data obtained as part of standard of care will be collected from the medical record
OTHER	Neuroimaging volumetric measures	Neuroimaging volumetric measures will be obtained from already conducted standard of care neuroimaging.
OTHER	Biofluid samples	Biofluid sampling data will be obtained through another protocol. All participants will be required to sign that consent to participate in this trial.

Timeline

• Start date: 2026-12-01
• Primary completion: 2032-01-01
• Completion: 2032-01-01
• First posted: 2024-08-07
• Last updated: 2026-02-25

Locations

1 site across 1 country: United States