NCT05225181

Effects of the Combining Physical Exercise and Cognitive Training for the Community-based Elderly

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 90 (estimated)
• Sponsor: Chang Gung Memorial Hospital · Academic / Other
• Sex: All
• Age: 60 Years
• Healthy volunteers: Accepted

Summary

This study aims to (1) determine the intervention effects of sequential and simultaneous training on cognitive function and health-related function for cognitively-normal elderly and elderly with Mild Cognitive Impairment(MCI) and Subjective Cognitive Decline(SCD); (2) compare which combination approach is more advantageous for improvement on outcome measures.

Detailed description

The investigators will recruit 30 cognitively-normal elderly and 30 elderly with Mild Cognitive Impairment(MCI) and 30 elderly with Subjective Cognitive Decline(SCD). Participants will be randomly assigned to one of three groups: sequential training (first perform physical exercise followed by cognitive training), simultaneous training (perform physical exercise and cognitive tasks simultaneously), and control group (perform body stretching and health education courses). All participants will receive trainings for 120 minutes per day, one day per week for 12 weeks. The outcome will include measurements that evaluate the cognitive, physical, daily functions, quality of life, and social participation. Participants will be assessed at baseline, after the intervention, and at 3-month follow-up. Repeated measures of analysis of variance (ANOVA) will be used to evaluate the changes in outcome measures at three different time points for the elderly with cognitively-normal, Mild Cognitive Impairment(MCI) and Subjective Cognitive Decline(SCD), respectively. The investigators also use the analysis of covariance (ANCOVA) to investigate the differences between the Mild Cognitive Impairment(MCI) and Subjective Cognitive Decline(SCD) groups on the outcome measures.

Conditions

• Cognitively-normal
• Mild Cognitive Impairment
• Subjective Cognitive Decline

Interventions

Type	Name	Description
BEHAVIORAL	perform physical exercise	one 60-min session of physical training
BEHAVIORAL	cognitive training	one 60-min session of cognitive training
BEHAVIORAL	control group	perform body stretching(15min) and health education courses(90min)

Timeline

• Start date: 2022-03-01
• Primary completion: 2023-12-31
• Completion: 2023-12-31
• First posted: 2022-02-04
• Last updated: 2022-02-24

Locations

1 site across 1 country: Taiwan