| Not Yet Recruiting | Safety and Tolerability of IRX-101 in Patients Receiving Intravitreal Injections NCT05750589 | iRenix Medical, Inc. | Phase 3 |
| Recruiting | Advancing Pediatric Retinal Imaging With Auto-aligned OCT NCT06841575 | Duke University | N/A |
| Not Yet Recruiting | A Multimodal AI Agent for Ophthalmic Clinical Decision Support NCT07401459 | The Hong Kong Polytechnic University | N/A |
| Withdrawn | Peripheral Retina Robotically Aligned OCT Study NCT06451068 | Duke University | N/A |
| Recruiting | CHOPXE - Analysis of Choriocapillaris Flow Deficits in Patients With Pseudoxanthoma Elasticum NCT07006649 | University Hospital, Angers | N/A |
| Recruiting | Longitudinal Observational Study of Diabetic Retinopathy Progression in Type 2 Diabetes Patients NCT07458516 | Association for Innovation and Biomedical Research on Light and Image | — |
| Recruiting | The Genetics Navigator: Evaluating a Digital Platform for Genomics Health Services NCT06455384 | Unity Health Toronto | N/A |
| Recruiting | Data Gathering for A10900 NCT07149740 | Optos, PLC | — |
| Recruiting | Study to Evaluate Sepofarsen in Subjects With Leber Congenital Amaurosis (LCA) Type 10 (HYPERION) NCT06891443 | Laboratoires Thea | Phase 3 |
| Recruiting | A Repeat-Dose, Open-Label, Two Arm Safety and Efficacy Study of Two Doses of VP-001 Administered Intravitreall NCT06852963 | PYC Therapeutics | Phase 1 / Phase 2 |
| Recruiting | Study to Evaluate Ultevursen in Subjects With Retinitis Pigmentosa (RP) Due to Mutations in Exon 13 of the USH NCT06627179 | Laboratoires Thea | Phase 2 |
| Recruiting | Perfluorooctyl Bromide Which Empowers the Liquid to Flat the Detached Retina and Displace the Underneath Fluid NCT05699096 | EL Romany Ophthalmics Factory | — |
| Recruiting | COmparison of Clarus and Optos Ultrawide Field Imaging Systems for Inherited Retinal Disease NCT06380075 | University of Wisconsin, Madison | N/A |
| Completed | MAD of IVT VP-001 in PRPF31 Mutation-Associated Retinal Dystrophy Subjects (Wallaby) NCT06455826 | PYC Therapeutics | Phase 1 |
| Recruiting | Safety & Efficacy of Eyecyte-RPE™ in Patients With Geographic Atrophy Secondary to Dry Age-related Macular Deg NCT06394232 | Eyestem Research Pvt. Ltd. | Phase 1 / Phase 2 |
| Recruiting | A Efficacy and Safety Study of Ranibizumab 10mg/ml Injection (Incepta) in Patients With Diabetic Macular Edema NCT06305416 | Incepta Pharmaceuticals Ltd | Phase 3 |
| Active Not Recruiting | Safety and Efficacy Study of IVB102 Injection in Subjects With X-linked Retinoschisis NCT06289452 | InnoVec Biotherapeutics Inc. | EARLY_Phase 1 |
| Recruiting | Safety and Efficacy of 18 mm Short Vitrectomy Probe for Pediatric Vitreoretinal Surgeries NCT06520410 | Chang Gung Memorial Hospital | Phase 4 |
| Recruiting | P200TxE Diseased Eye Image Collection NCT06269666 | Optos, PLC | N/A |
| Recruiting | Optimize Pediatric OCT Imaging NCT06139523 | Duke University | — |
| Completed | Assess the Efficacy and Safety of Repeat Intravitreal Injections of Foselutoclax (UBX1325) in Patients With DM NCT06011798 | Unity Biotechnology, Inc. | Phase 2 |
| Enrolling By Invitation | A Long-Term Follow-Up Study in Subjects Who Received vMCO-I Administered Via Intravitreal Injection NCT05921162 | Nanoscope Therapeutics Inc. | — |
| Completed | Adaptive Optics ScanningLaser Ophthalmoscope Safety and Efficacy Clinical Trial NCT06173414 | Robotrak Technologies Co., Ltd. | — |
| Unknown | Structural Imaging Assisted Retinal Fluorescence Lifetime Imager (STARFLI) NCT05819307 | Insel Gruppe AG, University Hospital Bern | — |
| Completed | Fundus Findings and Thiol-Disulfide Homeostais NCT05958927 | Suzan Dogruya | — |
| Completed | SteRilizing Eye SoLution to ImprovE Patient ComFort (RELIEF) NCT05747430 | iRenix Medical, Inc. | Phase 2 |
| Active Not Recruiting | Investigating Geographic Atrophy Insights (i-GAIN) Natural History Study NCT05797896 | Complement Therapeutics | — |
| Completed | Dose Optimization for Safe and Efficient Fluorescein Angiography (DOSE Study) NCT05664555 | Seoul National University Bundang Hospital | Phase 4 |
| Completed | Assessment of an Automated Optical Coherence Tomography and Camera : Effectiveness of Vision-700 NCT06496763 | Crystalvue Medical Coporation | — |
| Recruiting | Color Fundus Photograph With Experts Labelling NCT06287645 | Pakistan Council of Scientific and Industrial Research | — |
| Completed | Study to Compare the Diopsys NOVA and LKC RETeval Devices NCT05416268 | Diopsys, Inc. | N/A |
| Enrolling By Invitation | Retina BioBank: Retina Biomarkers for a Deeper Understanding of Vitreoretinal and Systemic Diseases NCT06796673 | Greater Houston Retina Research | — |
| Unknown | Repeatability of Electroretinogram and Visual Evoked Potential NCT05334875 | Benha University | N/A |
| Unknown | Multifocal Electroretinogram in Normal Egyptian Population NCT05323032 | Benha University | N/A |
| Unknown | Ophthalmologic Outcomes in Patients With Carotid Artery Stenosis NCT05623293 | Universidade do Porto | — |
| Terminated | Study to Evaluate the Efficacy Safety and Tolerability of QR-421a in Subjects With RP Due to Mutations in Exon NCT05176717 | Laboratoires Thea | Phase 2 / Phase 3 |
| Terminated | Study to Evaluate the Efficacy Safety and Tolerability of Ultevursen in Subjects With RP Due to Mutations in E NCT05158296 | Laboratoires Thea | Phase 2 / Phase 3 |
| Unknown | High Resolution Optical Coherence Tomography NCT05130385 | Insel Gruppe AG, University Hospital Bern | — |
| Terminated | Effectiveness of Periocular Drug Injection in CATaract Surgery NCT05158699 | Luigi Rondas | Phase 3 |
| Completed | Characterization of Retinal Disease Progression in Eyes With Non Proliferative Diabetic Retinopathy in Diabete NCT04636307 | Association for Innovation and Biomedical Research on Light and Image | — |
| Completed | Retinal Surgery With or Without Anesthesiologist, Comparison of Surgeon and Patient's Comfort NCT04956237 | Hopital Foch | — |
| Unknown | Epidemiologic Assessment of Diabetic Retinopathy in Egypt Using Ultrawide Field Fundus Photographs NCT04935749 | Alexandria University | — |
| Completed | RPE Characterisation With Transscleral Optical Phase Imaging in Retinal Disorders NCT04912622 | Luzerner Kantonsspital | N/A |
| Terminated | Data Collection With the P200TE and P200TxE NCT05615896 | Optos, PLC | N/A |
| Unknown | An Open-label, Dose Escalation and Double-masked, Randomized, Controlled Trial Evaluating Safety and Tolerabil NCT04855045 | ProQR Therapeutics | Phase 2 / Phase 3 |
| Completed | Study to Gather Information on the Safety and Use of Aflibercept Injections Into the Eye for the Treatment of NCT04137120 | Bayer | — |
| Completed | Retinal Changes in Vitamin D Deficiency NCT04891211 | Adiyaman University | N/A |
| Terminated | A Multiple Dose Study of Repeat Intravitreal Injections of GEM103 in Neovascular Age-related Macular Degenerat NCT04684394 | Gemini Therapeutics, Inc. | Phase 2 |
| Completed | Evaluation of the Heidelberg Engineering SPECTRALIS With Flex Module for In-vivo Imaging in the Supine Positio NCT04661124 | Heidelberg Engineering GmbH | — |
| Terminated | Assessment of Visual Function in Ophthalmic Disorders Using Virtual Visual Field Analysis NCT04110015 | New York City Health and Hospitals Corporation | — |
| Completed | Retinal Imaging With Oblique Illumination NCT04398394 | Moser Christophe | N/A |
| Unknown | Comparison of Wide-field Retinal Imaging NCT04255732 | Prim. Prof. Dr. Oliver Findl, MBA | N/A |
| Terminated | A Multiple Dose Study of Repeat Intravitreal Injections of GEM103 in Dry Age-related Macular Degeneration NCT04643886 | Gemini Therapeutics, Inc. | Phase 2 |
| Completed | Accuracy of the Red Reflex Test in the Pediatric Population NCT04125043 | Children's National Research Institute | — |
| Completed | Agreement and Precision Study of the Nidek Mirante NCT04318132 | Nidek Co. LTD. | N/A |
| Completed | First in Human Study to Evaluate the Safety and Tolerability of GEM103 in Geographic Atrophy Secondary to Dry NCT04246866 | Gemini Therapeutics, Inc. | Phase 1 |
| Active Not Recruiting | A Study to Evaluate the Safety and Tolerability of QR-1123 in Subjects With Autosomal Dominant Retinitis Pigme NCT04123626 | ProQR Therapeutics | Phase 1 / Phase 2 |
| Unknown | Effects of Internal Limiting Membrane Peeling on Visual Function in Epiretinal Membrane Surgery NCT04130841 | Seoul National University Hospital | N/A |
| Unknown | Single Ascending Dose Study in Participants With LCA10 NCT03872479 | Editas Medicine, Inc. | Phase 1 / Phase 2 |
| Completed | Study Comparing the P200TxE and P200DTx NCT03964831 | Optos, PLC | N/A |
| Completed | Navigated OCT Imaging With the P200TxE NCT04003831 | Optos, PLC | N/A |
| Terminated | Extension Study to Study PQ-110-001 (NCT03140969) NCT03913130 | Laboratoires Thea | Phase 1 / Phase 2 |
| Completed | Correlation of Microvascular Ophthalmic Disease With Macrovascular Coronary Artery Disease in Trinidad NCT04233619 | The University of The West Indies | — |
| Active Not Recruiting | A Study to Evaluate Efficacy, Safety, Tolerability and Exposure After a Repeat-dose of Sepofarsen (QR-110) in NCT03913143 | ProQR Therapeutics | Phase 2 / Phase 3 |
| Completed | Study to Evaluate Safety and Tolerability of QR-421a in Subjects With RP Due to Mutations in Exon 13 of the US NCT03780257 | ProQR Therapeutics | Phase 1 / Phase 2 |
| Completed | Optos P200TE Agreement and Precision Study NCT03868462 | Optos, PLC | N/A |
| Terminated | GTSCOPE - To Evaluate the Natural Progression of Dry Age-related Macular Degeneration (AMD) NCT03894020 | Gyroscope Therapeutics Limited | — |
| Completed | Pain During Pars Plana Vitrectomy With Sub-tenon Anesthesia NCT03902925 | University of Sao Paulo | Phase 1 / Phase 2 |
| Unknown | Rapid Computerized Visual Acuity Test NCT05447845 | Rambam Health Care Campus | — |
| Unknown | Changes in Retinal Nerve Fiber Layer Thickness Detected by OCT in Diabetic Retinopathy After Panretinal Photoc NCT03786146 | Assiut University | — |
| Terminated | FOCUS: A Phase I/II First in Human Study to Evaluate the Safety and Efficacy of GT005 Administered in Subjects NCT03846193 | Gyroscope Therapeutics Limited | Phase 1 / Phase 2 |
| Completed | Performance of Long-wavelength Autofluorescence Imaging NCT03592017 | Oxford University Hospitals NHS Trust | N/A |
| Recruiting | Intraoperative OCT Guidance of Intraocular Surgery II NCT03713268 | Duke University | — |
| Withdrawn | Effect of Vitrectomy on the Evolution of Refractory Diabetic Macular Edema NCT03603990 | Fondation Ophtalmologique Adolphe de Rothschild | N/A |
| Unknown | Pars Plana Vitrectomy Alone in the Treatment of Macular Schisis in High Myopic Eyes NCT03586193 | Aier School of Ophthalmology, Central South University | — |
| Completed | Study to Compare Kowa OCT Bi-μ and the Optovue iVue 100 NCT03505567 | Kowa Research Institute, Inc. | N/A |
| Completed | Natural History Study of CEP290-Related Retinal Degeneration NCT03396042 | Editas Medicine, Inc. | — |
| Unknown | Polarization Perception in Health and Disease. Testing a New Sight Test NCT03823092 | South Warwickshire NHS Foundation Trust | — |
| Recruiting | Diagnostic Possibilities in Ophthalmological Diseases Using Swept Source Optical Coherence Tomography NCT06074731 | Johannes Kepler University of Linz | — |
| Completed | VEGF Concentrations After Intravitreal Bevacizumab vs Ranibizumab as a Treatment for Type 1 ROP NCT03148132 | Universidad Autonoma de San Luis Potosí | Phase 4 |
| Unknown | Perifoveal Vascular Network Assessed by OCT-Angiography in Type I Diabetes Mellitus NCT03422965 | Hospital Clinic of Barcelona | N/A |
| Completed | Investigation of Vascular Pathology in Eye Diseases Using Using Optical Coherence Tomography Angiography (OCT- NCT02811536 | Insel Gruppe AG, University Hospital Bern | — |
| Unknown | Side-by-Side Comparison of P200TE and Spectral OCT/SLO on Diseased Eyes NCT02921568 | Optos, PLC | N/A |
| Completed | The EASE Study - Human Factor and Usability Testing of a Binocular OCT System NCT02822612 | University College, London | — |
| Completed | The Effect of Eyemasks on Neonatal Stress Following Dilated Retinal Examination NCT03824782 | Sunnybrook Health Sciences Centre | N/A |
| Terminated | Defining Retinal and Choroidal Structures Using Hyperspectral Imaging NCT07530783 | Center for Eye Research Australia | N/A |
| Completed | Nutraceutical Support With Omega-3 NCT03712670 | Università degli Studi di Brescia | N/A |
| Recruiting | Stem Cell Ophthalmology Treatment Study II NCT03011541 | MD Stem Cells | N/A |
| Enrolling By Invitation | Smartphone Screening for Eye Diseases NCT03076697 | University of Michigan | — |
| Completed | Assessment of Novel Intraocular Injection Guide NCT02315170 | Maturi, Raj K., M.D., P.C. | N/A |
| Recruiting | Inherited Retinal Degenerative Disease Registry NCT02435940 | Foundation Fighting Blindness | — |
| Completed | Stem Cell Models of Best Disease and Other Retinal Degenerative Diseases. NCT02162953 | Mayo Clinic | — |
| Completed | OCT Agreement and Crossed Precision Study NCT02050880 | Nidek Co. LTD. | — |
| Withdrawn | Erythrocyte Ghost Mediated Retinal Diagnosis NCT02445001 | Northwell Health | N/A |
| Completed | Color Vision as a Measure for Inherited Retinal Diseases NCT01878032 | National Eye Institute (NEI) | — |
| Unknown | Stem Cell Ophthalmology Treatment Study NCT01920867 | MD Stem Cells | N/A |
| Recruiting | National Eye Institute Biorepository for Retinal Diseases NCT01496625 | National Eye Institute (NEI) | — |
| Terminated | Finasteride for Chronic Central Serous Chorioretinopathy NCT01585441 | National Eye Institute (NEI) | Phase 2 |
| Completed | Topical Interferon Gamma-1b for Central Serous Chorioretinopathy NCT01468337 | National Eye Institute (NEI) | Phase 1 / Phase 2 |
| Recruiting | Cell Collection to Study Eye Diseases NCT01432847 | National Eye Institute (NEI) | — |
| Completed | Trial of Subretinal Injection of (rAAV2-VMD2-hMERTK) NCT01482195 | King Khaled Eye Specialist Hospital | Phase 1 |
| Completed | Nidek RS3000 Comparative Study NCT01384487 | Nidek Co. LTD. | — |
| Completed | Extension Study for the Evaluation of Finasteride in the Treatment of Chronic Central Serous Chorioretinopathy NCT01227993 | National Eye Institute (NEI) | Phase 1 / Phase 2 |
| Recruiting | Genotype-Phenotype Study of Patients With Plaquenil -Induced Retinal Toxicity, With Evaluation of the ABCA4 Ge NCT01145196 | National Eye Institute (NEI) | — |
| Completed | A Phase 3 Study To Compare The Efficacy And Safety Of 0.3 MG Pegaptanib Sodium To Sham Injections In Subjects NCT01100307 | Pfizer | Phase 3 |
| Completed | Pilot Study for the Evaluation of Finasteride in the Treatment of Chronic Central Serous Chorioretinopathy NCT00837252 | National Eye Institute (NEI) | Phase 1 / Phase 2 |
| Unknown | Cpap at Delivery Room for Preterm Infants NCT01024361 | University of Sao Paulo | Phase 4 |
| Completed | Topcon 3D OCT-1000 Optical Coherence Tomography System NCT00792259 | Topcon Medical Systems, Inc. | — |
| Completed | Intravitreal Bevasizumab VS Sham Treatment in Acute BRVO: A Randomized Clinical Trial NCT00370851 | Shahid Beheshti University of Medical Sciences | Phase 3 |
| Terminated | Hematopoietic Stem Cell Transplantation in Autoimmune-Related Retinopathy(ARRON) NCT00278486 | Richard Burt, MD | Phase 1 |
| Completed | Optical Coherence Tomography Comparative Study NCT00069199 | National Eye Institute (NEI) | — |
| Completed | Research Study in Patients With Persistent Macular Edema NCT00035906 | Allergan | Phase 2 |
| Completed | Evaluation and Treatment of Patients With Inflammatory Eye Diseases NCT00006188 | National Eye Institute (NEI) | — |
| Completed | Evaluation and Treatment of Patients With Retinal Disease NCT00005784 | National Eye Institute (NEI) | — |
| Completed | HAT in Eye Complications of Behcet's Disease NCT00001865 | National Eye Institute (NEI) | Phase 2 |
| Completed | Screening for Studies on Retinovascular Diseases NCT00001733 | National Eye Institute (NEI) | — |
| Terminated | Tissue Studies of Human Eye Diseases NCT00001310 | National Eye Institute (NEI) | — |