NCT04255732

Comparison of Wide-field Retinal Imaging

Comparison Between Two Wide-field Imaging Systems on the Extent of Retinal Periphery Area Viewing

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Prim. Prof. Dr. Oliver Findl, MBA · Academic / Other
• Sex: All
• Age: 21 Years
• Healthy volunteers: Accepted

Summary

Fundus imaging has become an integral tool in retinal diagnosis. Although single-field fundus photography covers a vital region of the retina, it leaves a large portion of the periphery undiscovered. Ultra-wide-field imaging systems allowed for visualization of peripheral perfusion abnormalities in myopic eyes that were previously unknown. In Austria, there are two different wide-field imaging systems available. The first device on the market was the Optos (Optos PLC, Dunfermline, UK) and several years later the Clarus 500 (Carl Zeiss, Meditec AG, Jena, Germany) was introduced.

Detailed description

While both of the studied imaging systems have the possibility of a 200° view of the retina, we would asses if the differences between the two devices affect the extent of retinal periphery view and if ocular ametropies which come with different retinal pathologies would affect the retinal periphery assessment. Aim: To compare two CE-marked imaging systems concerning the extent of retinal periphery area viewing. We would like to perform a prospective observational study that would include patients divided into three groups: myopic patients, hyperopic and emmetropic patients. Fundus photography will be performed using two ultra-wide-field imaging systems (Optos, Daytona, Optos PLC, Dunfermline, UK and Clarus, 500 Carl Zeiss, Meditec AG, Jena, Germany), performed by the same investigator. All images with sufficient quality will be exported and saved to hard-disk. The difference in periphery view will be investigated as follows: two retinal photos for each patient will be imported into Photoshop CS6 image-editing system (Adobe, version 13.0.0) where the anatomical landmarks will be matched for each image and the borders will be compared to see if there are differences in retinal periphery area viewing between the two devices.

Conditions

• Retinal Disease

Interventions

Type	Name	Description
DEVICE	extent of retinal area viewing Optos, Daytona, Optos PLC, Dunfermline, UK	Comparison of the extent of retinal periphery view between two wide field imaging devices.
DEVICE	extent of retinal area viewing Clarus, 500 Carl Zeiss, Meditec AG, Jena, Germany	Comparison of the extent of retinal periphery view between two wide field imaging devices.

Timeline

• Start date: 2020-08-07
• Primary completion: 2020-10-01
• Completion: 2020-10-01
• First posted: 2020-02-05
• Last updated: 2020-10-06

Locations

1 site across 1 country: Austria