Trials / Completed
CompletedNCT03712670
Nutraceutical Support With Omega-3
Treatment of Exudative Age-Related Macular Degeneration With Aflibercept Combined With Pranoprofen Eye Drops or Nutraceutical Support With Omega-3: A Randomized Trial
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 60 (actual)
- Sponsor
- Università degli Studi di Brescia · Academic / Other
- Sex
- All
- Age
- 40 Years
- Healthy volunteers
- Not accepted
Summary
Although evidence have clearly proved that intravitreal injection of vascular endothelial growth factor antagonists prevents vision loss and may even improve visual acuity in patients with neovascular AMD, a significant percentage of patients continue to lose visual acuity. Moreover, monthly intravitreal injections represent a burden for society as well as the caregiver. Combination therapy with either topical 0.1% pranoprofen or nutraceutical support with AREDS2 formula plus omega-3 might act synergistically with intravitreal injection, offering valuable therapeutic support to aflibercept injections in patients requiring long-term treatment.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Aflibercept | monthly intravitreal injections |
| DRUG | Pranoprofen | 0.1% pranoprofen 3 times a day topical eye drops administration |
| DIETARY_SUPPLEMENT | Carotenoids | daily supplementation of nutraceutical tablets containing the AREDS2 formulation |
Timeline
- Start date
- 2016-01-01
- Primary completion
- 2016-12-31
- Completion
- 2017-03-15
- First posted
- 2018-10-19
- Last updated
- 2018-10-19
Source: ClinicalTrials.gov record NCT03712670. Inclusion in this directory is not an endorsement.