NCT04130841

Effects of Internal Limiting Membrane Peeling on Visual Function in Epiretinal Membrane Surgery

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 135 (actual)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: All
• Age: 19 Years
• Healthy volunteers: Not accepted

Summary

The patients who are diagnosed with idiopathic epiretinal membrane and scheduled to undergo epiretinal membrane removal will be treated with conventional vitrectomy and the epiretinal membrane will be removed. After removal of the epiretinal membrane, indocyanine green staining will be used to determine the internal limiting membrane (ILM) peeled off with the epiretinal membrane. (Group 1: spontaneous ILM peeling) If it is confirmed that the internal limiting membrane is not peeled together, the investigators determine whether the active Internal limiting membrane peeling is performed by 1:1 randomization immediately during surgery. (Group 2: Active ILM peeling, Group 3: no ILM peeling) The outcomes of the three groups will be compared.

Conditions

• Retinal Disease
• Epiretinal Membrane

Interventions

Type	Name	Description
PROCEDURE	Internal Limiting Membrane Peeling	After removal of the epiretinal membrane, indocyanine green staining will be used to determine the internal limiting membrane (ILM) peeled off with the epiretinal membrane. (Group 1: spontaneous ILM peeling) If it is confirmed that the internal limiting membrane is not peeled together, the investigators determine whether the active Internal limiting membrane peeling is performed by 1:1 randomization immediately during surgery. (Group 2: Active ILM peeling, Group 3: no ILM peeling) The outcomes of the three groups will be compared.

Timeline

• Start date: 2019-09-30
• Primary completion: 2021-09-29
• Completion: 2021-12-31
• First posted: 2019-10-17
• Last updated: 2021-09-23

Locations

1 site across 1 country: South Korea